{"id":164559,"url":"https://alion.io/job/insitro-senior-machine-learning-scientist-imaging","title":"Senior Machine Learning Scientist, Imaging","company":{"id":58624,"name":"insitro","domain":"insitro.com","url":"https://alion.io/company/insitro","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Ashby","truth_index":{"grade":"B","score":83,"open_postings":4,"ghost_share":0,"stale_share":0.5,"repost_share":0,"time_to_fill_p50_days":96,"computed_at":"2026-10-17T05:46:00Z"}},"role":"AI/ML","role_family":"AI/ML","seniority":"senior","employment_type":"full_time","work_mode":"hybrid","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["South San Francisco, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":173000,"max_usd":330000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":1213},"experience_years_min":2,"visa_sponsorship":false,"relocation_package":false,"has_equity":true,"technologies":[{"name":"AI Agents","optional":false},{"name":"Computer Vision","optional":false},{"name":"Keras","optional":false},{"name":"Machine Learning","optional":false},{"name":"Python","optional":false},{"name":"PyTorch","optional":false},{"name":"TensorFlow","optional":false},{"name":"AWS","optional":true},{"name":"Azure","optional":true},{"name":"Multimodal AI","optional":true},{"name":"SQL","optional":true},{"name":"Time Series Forecasting","optional":true}],"status":"live","first_seen_at":"2026-02-17T18:34:12Z","employer_posted_date":"2026-02-17","last_verified_at":"2026-10-18T04:00:56Z","board_verified":true,"closed_at":null,"days_open":242,"trust":{"level":"stale","repost_count":0,"flags":["stale"],"days_open":242},"description":"The Opportunity\nImaging based phenotyping of in-vitro biology is at the heart of insitro's efforts to accelerate drug development. At insitro, we use machine learning to derive clinically relevant insights from rich datasets generated in-house.\nAs an Imaging ML Scientist, you will develop ML-empowered computer vision pipelines to extract insights about disease mechanisms from multiple microscopy modalities. You will be part of a cross-functional team of life scientists, software engineers, computational biologists, and machine learning scientists that strive to identify therapeutic targets and develop drugs of high efficacy and low toxicity.\nYou will be joining a vibrant biotech startup that is in a high growth phase, with promising multiple pre-clinical drug targets in areas such as ALS and metabolic disease. A lot can change in this exciting phase, providing many opportunities for significant impact. You will work closely with a very talented team, learn a broad range of skills, and help shape insitro's culture, strategic direction, and outcomes.\nThis role will be reporting to the Director of Imaging, Cellular Machine Learning. This is a hybrid position that requires you to be in our South San Francisco headquarters at least three days per week. Join us, and help make a difference to patients!\nResponsibilities\nPartner with experimental and computational biologists to design, troubleshoot, and optimize high-throughput imaging-based experiments and workflows\n\nIdentify, understand, develop, and deploy novel computer vision and machine learning methods such as segmentation, feature extraction, and representation learning to extract features from microscopy image datasets\n\nWork closely with software engineers to build robust and well-tested image analysis workflows, able to be used by experimental and computational biologists with minimal direct support\n\nCalibrate analysis tools and workflows, define performance metrics, and conduct benchmarking to select fit-for-purpose solutions\n\nCommunicate findings to cross-functional stakeholders through reports, visualizations, presentations, and publications\n\nIdentify novel disease-relevant phenotypes and propose new screening paradigms that translate to actionable program decisions\n\nAbout You\nPh.D. in computer vision, machine learning, computer science or a related discipline, or equivalent practical experience (e.g., a Master's degree and 2+ years of relevant industry experience)\n\nAbility to communicate effectively and collaborate with people of diverse backgrounds and job functions on a daily basis\n\nDemonstrated ability to identify, understand, and find novel applications of state-of-the-art ML/CV methods from literature or other sources\n\nStrong programming skills in Python, including working with TB-scale image datasets and leveraging modern agentic software tools to accelerate development\n\nExperience developing models for diverse computer vision tasks (e.g. segmentation, recognition, classification, domain adaptation) including using modern deep learning frameworks (PyTorch, TensorFlow, Keras, etc)\n\nExtensive hands on experience working with microscopy data or similar biomedical or physical imaging modalities\n\nPassion for making a difference in the world\n\nNice to Have\nDemonstrated ability to write software in a team, industry experience or substantial involvement with open source projects.\n\nExperience modeling with video or imaging time-series datasets\n\nExperience with microscopy hardware, and/or image data acquisition in other contexts\n\nUnderstanding of optical physics, resolution, numerical aperture, etc.\n\nFamiliarity with cloud computing services (e.g., AWS or Azure)\n\nExperience with database languages (e.g., SQL)\n\nPublication record of meaningful contributions to high-quality work in relevant computer vision, clinical ML, or biomedical venues\n\nCompensation & Benefits at insitro\nOur target starting salary for successful US-based applicants for this role is $215,000 - $235,000. To determine starting pay, we consider multiple job-related factors including a candidate's skills, education and experience, market demand, business needs, and internal parity. We may also adjust this range in the future based on market data.\nThis role is eligible for participation in our Annual Performance Bonus Plan (based on company targets by role level and annual company performance) and our Equity Incentive Plan, subject to the terms of those plans and associated policies.\nIn addition, insitro also provides our employees:\n401(k) plan with employer matching for contributions\n\nExcellent medical, dental, and vision coverage as well as mental health and well-being support\n\nOpen, flexible vacation policy\n\nPaid parental leave of at least 16 weeks to support parents who give birth, and 10 weeks for a new parent (inclusive of birth, adoption, fostering, etc)\n\nQuarterly budget for books and online courses for self-development\n\nSupport to attend professional conferences that are meaningful to your career growth and role's responsibilities\n\nNew hire stipend for home office setup\n\nMonthly cell phone & internet stipend\n\nAccess to free onsite baristas and daily lunch for employees who are either onsite or hybrid\n\nAccess to a free commuter bus network that provides transport to and from our South San Francisco HQ from locations all around the Bay Area\n\ninsitro is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.\nWe believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams-grounded in a wide range of expertise and life experiences-and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.\nPlease be aware of recruitment scams: we never request payments, all recruitment communications are from @insitro.com, and if in doubt, contact us at .\nAbout insitro\ninsitro is a drug discovery and development company using machine learning (ML) and data at scale to decode biology for transformative medicines. At the core of insitro’s approach is the convergence of in-house generated multi-modal cellular data and high-content phenotypic human cohort data. We rely on these data to develop ML-driven, predictive disease models that uncover underlying biologic state and elucidate critical drivers of disease. These powerful models rely on extensive biological and computational infrastructure and allow insitro to advance novel targets and patient biomarkers, design therapeutics and inform clinical strategy. insitro is advancing a wholly owned and partnered pipeline of insights and therapeutics in neuroscience and metabolism. Since launching in 2018, insitro has raised over $700 million from top tech, biotech and crossover investors, and from collaborations with pharmaceutical partners. For more information on insitro, please visit www.insitro.com.","description_format":"text","description_chars":7202,"description_truncated":false,"requirements":{"experience_years_min":2,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"master","optional":false},"security_clearance":false,"languages":[]},"benefits":["Equity","Flexible vacation policy","Home office","Parental leave"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Bioinformatics","Drug Discovery","Drug Discovery AI"],"lifecycle":[{"event":"open","at":"2026-02-17T18:34:12Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 11 · green card filings: 2","filings_12m":11,"filings_prev_12m":16,"green_card_filings_12m":2,"median_offered_wage_usd":110962,"route":null,"cap_exempt":false,"checked_at":"2026-10-15T11:24:14+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":1}],"liveness":{"score":14,"band":"cold","label":"Long shot","p_open":1,"p_active":0.509,"p_room":0.28,"age_days":241,"expected_fill_days":96,"reasons":["conf:0","win:tail","crowd:"],"computed_at":"2026-10-17T05:46:00Z"},"pay":null,"html_url":"https://alion.io/job/insitro-senior-machine-learning-scientist-imaging","json_url":"https://alion.io/job/insitro-senior-machine-learning-scientist-imaging.json","meta":{"generated_at":"2026-10-18T05:55:23Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":8848,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-19T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":58624},"rest":"https://alion.io/mcp/rest/get_company?id=58624"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Finsitro-senior-machine-learning-scientist-imaging"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Finsitro-senior-machine-learning-scientist-imaging"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Finsitro-senior-machine-learning-scientist-imaging"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/insitro-senior-machine-learning-scientist-imaging\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Finsitro-senior-machine-learning-scientist-imaging"}]}