{"id":2982726,"url":"https://alion.io/job/ionis-assistant-director-analytical-development-quality-control","title":"Assistant Director, Analytical Development & Quality Control","company":{"id":1953599,"name":"IONIS","domain":"ionis.com","url":"https://alion.io/company/ionis","size_band":"501-1000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"UltiPro","truth_index":null},"role":"Biotech","role_family":"Biotech","seniority":"head","employment_type":"full_time","work_mode":"remote","remote_scope":"stated_countries","remote_scope_basis":"board_field","remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Carlsbad, United States"],"countries":["US"],"hiring_countries":["US"],"hiring_countries_total":1,"salary":{"min":95411,"max":174695,"currency":"USD","period":"year","gross":null,"usd_annual":174695},"salary_estimate":null,"experience_years_min":8,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"GMP","optional":false},{"name":"HPLC","optional":false},{"name":"Mass Spectrometry","optional":false}],"status":"live","first_seen_at":"2026-10-07T22:25:01Z","employer_posted_date":"2026-10-07","last_verified_at":"2026-10-25T14:42:40Z","board_verified":true,"closed_at":null,"days_open":17,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":17},"description":"Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.\nAt Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.\nWith an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.\nWe’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!\nASSISTANT DIRECTOR, \n ANALYTICAL DEVELOPMENT & QUALITY CONTROL\nSeeking an experienced analytical chemist to join our Analytical Development & Quality Control (ADQC) group at the Assistant Director level. The ideal candidate will be familiar with a broad range of analytical chemistry techniques with an emphasis on mass spectrometry, possess a strong work ethic and strong technical background, demonstrate excellent oral and written communication skills, and have experience working in a GMP environment. The successful candidate will be able to perform the following responsibilities with a high degree of independence and attention to detail.\nWORK LOCATION: onsite in Carlsbad, CA\nRESPONSIBILITIES:\nManage the analytical activities for oligonucleotide therapeutic development projects\nCoordinate and execute testing of drug substance intermediate, drug substance, and drug product samples for release and stability studies\nManage outsourced analytical activities at external contract labs\nConduct analytical investigations\nDevelop and optimize analytical methods\nDevelop drug substance specifications ensuring efficient integration across Chemistry, Manufacturing, and Controls (CMC) and other relevant disciplines such as Clinical and Toxicology\nDesign and execute method validation and method transfer protocols\nAuthor scientific reports and portions of the CMC section of regulatory filings\nPresent at internal and cross-functional scientific meetings\nREQUIREMENTS:\nA minimum of 8 years for BS or 6 years with a Master's of industry experience in Analytical Chemistry or related discipline\nPh.D. with a minimum of 3 years of industry experience in Analytical Chemistry or a related discipline\nSkilled in operating LC-MS, HPLC, and GC for the analysis of drug substance and drug product samples\nGood understanding of the drug development process\nPractical knowledge of GMP requirements, with hands-on GMP experience preferred\nGood understanding of ICH and FDA method validation guidelines, including phase-appropriate strategies\nAbility to solve problems, manage priorities and maintain aggressive timelines for multiple projects\nAbility to work productively and independently within a team or matrix environment\nExcellent written and verbal communication skills\nPlease visit our website,http://www.ionis.com for more information about Ionis and to apply for this position; reference requisition # IONIS004157\nIonis offers an excellent benefits package! Follow this link for more details:Ionis Benefits\nFull Benefits Link: https://ionis.com/careers#:~:text=Highly%20competitive%20benefits\nThe pay scale for this position is $95,411 to $174,695\nNO PHONE CALLS PLEASE. PRINCIPALS ONLY.\nIonis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.","description_format":"text","description_chars":4436,"description_truncated":false,"requirements":{"experience_years_min":8,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"master","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Health Care"],"lifecycle":[{"event":"open","at":"2026-10-21T07:47:51Z"}],"visa":[],"liveness":{"score":76,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.846,"p_room":0.9,"age_days":17,"expected_fill_days":35,"reasons":["conf:2","win:mid"],"computed_at":"2026-10-25T05:49:26Z"},"pay":{"stated_usd_annual":174695,"is_top_pay":false},"html_url":"https://alion.io/job/ionis-assistant-director-analytical-development-quality-control","json_url":"https://alion.io/job/ionis-assistant-director-analytical-development-quality-control.json","meta":{"generated_at":"2026-10-25T15:14:06Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":21941,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-26T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":1953599},"rest":"https://alion.io/mcp/rest/get_company?id=1953599"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fionis-assistant-director-analytical-development-quality-control"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fionis-assistant-director-analytical-development-quality-control"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fionis-assistant-director-analytical-development-quality-control"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/ionis-assistant-director-analytical-development-quality-control\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fionis-assistant-director-analytical-development-quality-control"}]}