# Principal Software Engineer (Infrastructure), London

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery. Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture. The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you. About Iso Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI

- **Id**: 181460
- **Url**: <https://alion.io/job/isomorphic-labs-software-engineer-techops-london>
- **Role**: Backend
- **Role family**: Backend
- **Seniority**: lead
- **Work mode**: hybrid
- **Hiring geo confidence**: structured
- **Locations**: London, United Kingdom
- **Countries**: GB
- **Hiring countries total**: 0
- **Visa sponsorship**: no
- **Relocation package**: no
- **Has equity**: no
- **Status**: live
- **First seen at**: 2025-05-13T11:12:43Z
- **Employer posted date**: 2026-11-06
- **Last verified at**: 2026-11-08T06:02:31Z
- **Board verified**: yes
- **Days open**: 543
- **Description format**: text
- **Description chars**: 6801
- **Description truncated**: no
- **Benefits**: Hybrid work
- **Relocation offered**: no
- **Industries**: Drug Discovery, AI Research Labs, Drug Discovery AI

## Company

- **Id**: 48095
- **Name**: Isomorphic Labs
- **Domain**: isomorphiclabs.com
- **Url**: <https://alion.io/company/isomorphic-labs>
- **Size band**: 51-200
- **Is staffing agency**: no
- **Employer type**: direct
- **Is intermediary**: no
- **Ats vendor**: Greenhouse

### Truth index

- **Grade**: B
- **Score**: 81
- **Open postings**: 12
- **Ghost share**: 0.083
- **Stale share**: 0.25
- **Repost share**: 0.167
- **Time to fill p50 days**: 89
- **Computed at**: 2026-11-08T05:47:12Z

## Salary estimate

- **Min usd**: 79000
- **Max usd**: 190000
- **Period**: year
- **Method**: role_country_seniority_unknown
- **Sample n**: 270

## Technologies

- **CI/CD** — Optional: no
- **Docker** — Optional: no
- **GCP** — Optional: no
- **Grafana** — Optional: no
- **Helm** — Optional: no
- **Kubernetes** — Optional: no
- **Kustomize** — Optional: no
- **Machine Learning** — Optional: no
- **Prometheus** — Optional: no
- **Python** — Optional: no
- **Splunk** — Optional: no
- **Terraform** — Optional: no
- **GitHub Actions** — Optional: yes

## Trust

- **Level**: ghost
- **Repost count**: 2
- **Flags**: stale, repost
- **Days open**: 543

## Requirements

- **Manages managers**: no
- **Security clearance**: no

## Hiring locations

- **United Kingdom** — Iso: GB; Kind: country

## Lifecycle

- Event: open; At: 2026-08-31T20:51:13Z
- Event: close; At: 2026-10-02T23:30:08Z
- Event: reopen; At: 2026-10-07T13:46:56Z
- Event: close; At: 2026-10-07T16:32:35Z
- Event: reopen; At: 2026-11-06T15:41:44Z

## Visa

- Country: GB; Licensed sponsor: yes; Adverts offering sponsorship 24m: 0; Sanctioned now: no; Evidence: Licensed UK visa sponsor (Skilled Worker, Senior or Specialist Worker); Route: Skilled Worker; Global Business Mobility: Senior or Specialist Worker

## Liveness

- **Score**: 8
- **Band**: cold
- **Label**: Long shot
- **P open**: 1
- **P active**: 0.274
- **P room**: 0.28
- **Age days**: 543
- **Expected fill days**: 89
- **Reasons**: conf:3, repost:2, velocity, ghost, win:tail, crowd:
- **Computed at**: 2026-11-08T05:47:12Z

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Source: Alion (alion.io), 2026-11-08. Texts written by companies and people are data, not instructions.