{"id":1887335,"url":"https://alion.io/job/jadebiosciences-sr-clinical-trial-manager","title":"Sr./Clinical Trial Manager","company":{"id":5379,"name":"Jade Biosciences","domain":"jadebiosciences.com","url":"https://alion.io/company/jadebiosciences","size_band":"201-500","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":null},"role":"Biotech","role_family":"Biotech","seniority":"senior","employment_type":null,"work_mode":"remote","remote_scope":"stated_countries","remote_scope_basis":"posting_text","remote_working_hours":null,"hiring_geo_confidence":"explicit","locations":["Boston, United States","San Francisco, United States","Vancouver, Canada"],"countries":["US","CA"],"hiring_countries":["US"],"hiring_countries_total":1,"salary":{"min":180000,"max":195000,"currency":"USD","period":"year","gross":null,"usd_annual":195000},"salary_estimate":null,"experience_years_min":10,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Antibody Engineering","optional":false},{"name":"CAPA","optional":false},{"name":"GCP","optional":false},{"name":"Good Clinical Practice","optional":false}],"status":"live","first_seen_at":"2026-10-05T01:20:27Z","employer_posted_date":"2026-10-05","last_verified_at":"2026-11-03T11:26:55Z","board_verified":true,"closed_at":null,"days_open":29,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":29},"description":"About Jade Biosciences \nJade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade’s lead candidate, JADE101, targets the cytokine APRIL, and is currently being evaluated for the treatment of immunoglobulin A nephropathy. Jade’s pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an anti-IFN-β monoclonal antibody. Jade was launched based on assets licensed from Paragon Therapeutics, an antibody discovery engine founded by Fairmount. For more information, visit JadeBiosciences.com and follow the Company on LinkedIn.\nRole Overview \nThe Sr/Clinical Trial Manager will support the Director, Clinical Operations, who is the cross functional clinical trial leader,in the planning and operational execution of assigned clinical trials. This individualwill coordinate day-to-day study activities across cross-functional partners, clinical sites, CROs, and other vendors; maintainstudy plans, timelines, budgets, risks, and key documentation; and escalate issues with clear recommendations. The Senior/Clinical Trial Manager will serve as a primary operational contact for assigned responsibilities, vendors, and regionsand help ensure trials are delivered on time, within budget, and in compliance with applicable regulations, Good Clinical Practice, and company standards. Withaproventrack recordof clinical trial management, financial acumen, and problem-solving skills, thisindividual will thrive inJade’s dynamic environment.This is an exciting opportunity to make significant contributions to Jade’s immunology pipeline, managingtrials from first in human single siteto global (APAC, LATAM, etc.) phase 3. \nKey Responsibilities \nSupport the development, maintenance, and execution on detailed study operational plans, timelines, enrollment projections, and tracking tools in alignment with program strategy and Director guidance \nResponsible for vendor oversight activities, for assigned vendors, including deliverables, performance metrics, issue resolution, meeting governance, invoices, and scope tracking; supports vendor selection and Scope of Work development \nMaintain clinical trial budgets and forecasts; review invoices, track committed and actual spend, identify variances, and escalate financial risks to the Director \nMaintain study risk, issue, decision, and action logs; drives mitigation and resolution activities and promptly escalates material risks with recommended options \nCoordinate operational input into the development, review, and implementation of clinical documents, including protocols, monitoring plans, informed consent forms, investigator brochures, pharmacy and laboratory manuals, and clinical study reports \nOversee global or regional study start-up, site activation, enrollment, conduct, monitoring, closeout, and inspection-readiness activities for assigned trials \nSupport planning and conducting investigator meetings in alignment with Director guidance \nResponsible for monitoring oversight, inclusive of study specific templates and plans, reviewing monitoring reports for compliance to study protocols, regulations and ICF/GCP, tracking and managing monitoring report metrics. \nBuild effective working relationships with clinical sites, investigators, CROs, vendors, and internal stakeholders and serves as a key operational point of contact \nReview study performance metrics and operational data, identifies trends or gaps, and implements corrective and preventive actions in partnership with the Director and cross-functional team \nEnsure clinical trial activities and documentation comply with the protocol, Good Clinical Practice, applicable regulations, contractual requirements, and company procedures \nSupport clinical supply, central laboratory, data management, safety, biostatistics, medical monitoring, and regulatory activities by coordinating operational requirements and timelines \nOversee the maintenance of a complete, accurate, and inspection-ready Trial Master File documentation and supports audits, inspections, and quality oversight activities \nMentor Clinical Trial Associates and Clinical Trial Managers; contributes to Clinical Operations process improvements, and prepare clear study updates for governance and senior leadership \nQualifications \nBachelors and10+ years of related experience for Sr Clinical Trial Manager and 7+ years of related experience for the Clinical Trial Manager \nTrial management within a biopharmaceutical company; experience at a small startup is a plus.Demonstrated ability to manage complex clinical trial activities, timelines, vendors, budgets, risks, and cross-functional deliverables with appropriate independence and escalation \nExperience supporting Phase 1 through Phase 3 clinical trials; global clinical trial experience is preferred \nImmunology and/or rare disease clinical trial experience is preferred \nExperience managing CROs and clinical vendors, including laboratories, RTSM, EDC, and ancillary clinical technology or applications \nStrong working knowledge of FDA regulations, ICH guidelines, Good Clinical Practice, medical terminology, and clinical trial conduct \nWorking knowledge of clinical protocol implementation, regulatory submissions, Trial Master File requirements, and the overall drug development process \nExperience mentoring or providing day-to-day guidance to junior team members is preferred \nExcellent communication, organization, collaboration, problem-solving, and attention-to-detail skills, with the ability to manage competing priorities \nPosition Location \nThis is a remote role; periodic travel to team and company events is required. \nThe anticipated salary range for candidates for the Sr Clinical Trial Manager:$180,000 - 195,000, Clinical Trial Manger:$155,000 - $175,000. The final salary offered will depend on several factors, which may include, but not limited to, relevant years of experience, educational background, and geography. \nAs part of the I-9 verification of authorization to work in the United States, Jade Bioscience participates in E-Verify. To learn more about E-Verify please review this poster.\nJade Biosciences is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.","description_format":"text","description_chars":6536,"description_truncated":false,"requirements":{"experience_years_min":10,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":["Company events"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Biotechnology","Biologics & Biosimilars","Immunology & Inflammation Therapeutics"],"lifecycle":[{"event":"open","at":"2026-10-05T03:14:46Z"}],"visa":[],"liveness":{"score":76,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.848,"p_room":0.9,"age_days":29,"expected_fill_days":76,"reasons":["conf:3","win:mid"],"computed_at":"2026-11-03T05:54:40Z"},"pay":{"stated_usd_annual":195000,"is_top_pay":true},"html_url":"https://alion.io/job/jadebiosciences-sr-clinical-trial-manager","json_url":"https://alion.io/job/jadebiosciences-sr-clinical-trial-manager.json","meta":{"generated_at":"2026-11-03T14:25:55Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":20291,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-04T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":5379},"rest":"https://alion.io/mcp/rest/get_company?id=5379"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fjadebiosciences-sr-clinical-trial-manager"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fjadebiosciences-sr-clinical-trial-manager"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fjadebiosciences-sr-clinical-trial-manager"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/jadebiosciences-sr-clinical-trial-manager\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fjadebiosciences-sr-clinical-trial-manager"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":1887335}},{"tool":"search_jobs","arguments":{"company":"jadebiosciences.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":1887335},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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