{"id":1959127,"url":"https://alion.io/job/keros-therapeutics-contract-senior-it-infrastructure-engineer","title":"Contract Senior IT Infrastructure Engineer","company":{"id":3783050,"name":"Keros Therapeutics","domain":"kerostx.com","url":"https://alion.io/company/world-3783050","size_band":null,"is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":null},"role":"DevOps","role_family":"DevOps","seniority":"senior","employment_type":"contractor","work_mode":"hybrid","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Lexington, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":112000,"max_usd":215000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":1716},"experience_years_min":12,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"21 CFR Part 11","optional":false},{"name":"Azure","optional":false},{"name":"ITSM","optional":false},{"name":"Microsoft Entra ID","optional":false},{"name":"PowerShell","optional":false},{"name":"SIEM","optional":false},{"name":"Zero Trust","optional":false},{"name":"Zscaler","optional":false}],"status":"live","first_seen_at":"2026-10-06T14:27:56Z","employer_posted_date":"2026-10-06","last_verified_at":"2026-10-21T09:25:43Z","board_verified":true,"closed_at":null,"days_open":14,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":14},"description":"At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients.\nJob Summary\nThe Sr. IT Infrastructure Engineer is Keros' senior individual contributor for enterprise infrastructure, cloud, identity, endpoint, network, cybersecurity operations, and resilience. This role establishes technical direction, reference architectures, engineering standards, and long-range improvements across multiple related disciplines while remaining hands-on with the most critical and complex assignments. \nOperating with broad latitude, the Sr. Infrastructure Engineer advises IT leadership and key decision-makers, resolves issues affecting multiple functions, and guides the adoption of secure, scalable, supportable, and compliant technology platforms. The role provides technical direction and mentorship but does not carry formal people-management accountability.\nPrimary Responsibilities\n Sr. Technical Authority and Architecture\nServe as the Senior advisor and final technical escalation point for enterprise infrastructure, cloud, identity, endpoint, network, backup, and cybersecurity operations.\nDefine target architectures, engineering standards, reference patterns, technical roadmaps, and lifecycle strategies that support organizational goals and future requirements.\nEvaluate significant technology risks, dependencies, and design tradeoffs; make recommendations where precedent is limited and decisions affect multiple functions.\nCybersecurity Operations and Resilience\nEstablish technical direction for the Rapid7 security platform, security monitoring, vulnerability management, incident handling, remediation, detection coverage, and operational reporting.\nLead resolution of critical security and infrastructure events, including advanced troubleshooting, root-cause analysis, containment, recovery, corrective actions, and validated closure.\nDefine resilience, backup, recovery, hardening, and zero-trust engineering practices; guide testing and continuous improvement of those controls.\nCloud, Identity, Endpoint, and Network Engineering\nLead the architecture and continual improvement of Microsoft cloud, identity, endpoint, collaboration, application-deployment, automation, and patch-management services.\nGuide enterprise networking, secure access, office and lab connectivity, backup, recovery, and integration patterns for scientific systems and regulated business applications.\nDevelop automation and engineering solutions that improve reliability, security, observability, supportability, and operational efficiency across platforms.\nGovernance, Influence, and Technical Leadership\nGuide complex cross-functional initiatives and architecture decisions, building alignment among IT, cybersecurity, scientific, quality, finance, legal, and technology partners.\nEstablish and maintain architecture records, standards, SOPs, runbooks, technical decision documents, knowledge, and evidence required for sustainable operations and assurance.\nSupport GxP, SOX ITGC, 21 CFR Part 11, NIST Cybersecurity Framework, audits, vendor risk, and security assessments through technical leadership and control design.\nMentor engineers, review complex designs, and raise engineering capability through standards, reusable patterns, technical coaching, and knowledge transfer. \nTechnology Environment\nMicrosoft Azure, Microsoft 365, Entra ID, Intune, Defender, Rapid7, Cisco Meraki, Zscaler, Commvault, and Egnyte, along with additional enterprise, collaboration, security, and scientific platforms.\nCore Competencies (Required Skills)\nSenior-level expertise: Recognized expertise across enterprise infrastructure and several related disciplines, with the judgment to advise on critical issues and set technical direction.\nArchitecture and strategy: Demonstrated success defining standards, reference architectures, roadmaps, lifecycle strategies, and long-range solutions across multiple platforms.\nComplex problem solving: Ability to resolve significant and unique issues using conceptual thinking, limited precedent, independent judgment, and a long-term view.\nMicrosoft and automation: Deep Microsoft cloud, identity, endpoint, security, and PowerShell expertise.\nSecurity and resilience: Advanced experience with SIEM/XDR, vulnerability management, incident handling, network security, secure access, backup, recovery, and control engineering; Rapid7 strongly preferred.\nInfluence and technical leadership: Ability to guide critical assignments, align decision makers, mentor engineers, and drive adoption without formal authority.\nRegulated operations: Strong documentation, ITSM, change-management, risk, audit, and compliance discipline in environments handling sensitive or regulated information.\nPreferred Skills\nExperience in biotechnology, pharmaceutical, life sciences, healthcare, or another regulated industry.\nExperience guiding complex technology programs or standards that span infrastructure, cybersecurity, scientific systems, and corporate platforms.\nExperience with Rapid7, Cisco Meraki, Zscaler, Commvault, and scientific or lab technology environments.\nRelevant Microsoft, Rapid7, Cisco/Meraki, Zscaler, CISSP, CISM, GIAC, or comparable expert-level certifications.\nEducation Requirements\nBachelor's degree in Information Technology, Computer Science, Cybersecurity, Engineering, or a related field. Equivalent senior-level professional experience may be considered.\nMinimum of 12 years of progressive IT infrastructure, cloud, security operations, or systems-engineering experience, including Level 3 responsibilities.\nThis pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, and other relevant factors. \nPotential base pay range\n$95—$119 USD\n\nOur Diversity, Equity & Inclusion Mission Statement: Keros is an inclusive company. We believe that diversity drives innovation. We continue to build an inclusive culture that encourages, supports, and celebrates the diverse voices of our employees. As such, Keros takes a holistic approach in mentoring, coaching, and developing all of our Keros team members.\nKeros Therapeutics is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.\n Recruitment & Staffing Agencies:\n Keros Therapeutics does not accept unsolicited resumes from any source other than the candidate directly. Any unsolicited submission by an agency to Keros is prohibited. Any resume submitted by an agency without a signed contract or expressed consent by a member of the Keros Therapeutics Human Resources Department, will be considered property of Keros Therapeutics, and no fee shall be owed with respect thereto.","description_format":"text","description_chars":7628,"description_truncated":false,"requirements":{"experience_years_min":12,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":["Equity"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Biotechnology","Financial Services","Health Care","Information Security"],"lifecycle":[{"event":"open","at":"2026-10-06T14:33:09Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"Filed H-1B visas in the last two years","filings_12m":0,"filings_prev_12m":2,"green_card_filings_12m":0,"median_offered_wage_usd":null,"route":null,"cap_exempt":false,"checked_at":"2026-10-15T11:24:14+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)"],"filings_for_role_12m":0}],"liveness":{"score":73,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.814,"p_room":0.9,"age_days":14,"expected_fill_days":30,"reasons":["conf:1","win:mid"],"computed_at":"2026-10-21T05:46:15Z"},"pay":null,"html_url":"https://alion.io/job/keros-therapeutics-contract-senior-it-infrastructure-engineer","json_url":"https://alion.io/job/keros-therapeutics-contract-senior-it-infrastructure-engineer.json","meta":{"generated_at":"2026-10-21T09:37:34Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":13596,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-22T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":3783050},"rest":"https://alion.io/mcp/rest/get_company?id=3783050"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fkeros-therapeutics-contract-senior-it-infrastructure-engineer"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fkeros-therapeutics-contract-senior-it-infrastructure-engineer"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fkeros-therapeutics-contract-senior-it-infrastructure-engineer"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/keros-therapeutics-contract-senior-it-infrastructure-engineer\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fkeros-therapeutics-contract-senior-it-infrastructure-engineer"}]}