{"id":1592757,"url":"https://alion.io/job/korro-bio-senior-scientist","title":"Senior Scientist","company":{"id":683326,"name":"Korro Bio","domain":"korrobio.com","url":"https://alion.io/company/korrobio","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Lever","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":"senior","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Cambridge, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":160000,"max":180000,"currency":"USD","period":"year","gross":null,"usd_annual":180000},"salary_estimate":null,"experience_years_min":12,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Confluence","optional":false},{"name":"Jira","optional":false}],"status":"live","first_seen_at":"2026-10-01T13:27:03Z","employer_posted_date":"2026-10-01","last_verified_at":"2026-10-21T05:21:18Z","board_verified":true,"closed_at":null,"days_open":19,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":19},"description":"Korro is a biopharmaceutical company focused on developing a new class of genetic medicines for both rare and highly prevalent diseases using its proprietary RNA editing platform. Korro is generating a portfolio of differentiated programs that are designed to harness the body’s natural RNA editing process to effect a precise yet transient single base edit. By editing RNA instead of DNA, Korro is expanding the reach of genetic medicines by delivering additional precision and tunability, which has the potential for increased specificity and improved long-term tolerability. Using an oligonucleotide-based approach, Korro expects to bring its medicines to patients by leveraging its proprietary platform with precedented delivery modalities, manufacturing know-how, and established regulatory pathways of approved oligonucleotide drugs. Korro’s lead program is for Urea Cycle Disorders. Korro is based in Cambridge, Massachusetts. For more information, visit korrobio.com.\nWe are collaborative and united by a common mission. We are building a company with extraordinary people with an audacious vision to create transformative genetic medicines for prevalent diseases. Our values - Rewrite the future, On the Cutting Edge, Better Together, Dynamically Different, Kindness and Integrity form the fabric of the organization. They are reinforced daily and serve as key dimensions in the hiring process to help us ensure that Korro is a magnet for outstanding talent and a great place to work. Join us as we redefine what's possible in genetic medicine and work to make a lasting impact on human health.\nPosition Summary\nKorro Bio is seeking an experienced Senior Scientist to lead our HTS-NGS team in support of our oligonucleotide platform and portfolio projects. This is a hybrid leadership and hands-on role that requires a combination of scientific expertise, team management, and cross-functional collaboration. The ideal candidate brings deep technical knowledge in high-throughput cell assays and NGS workflows, along with leadership experience, to lead a key workflow in the identification of RNA editing therapeutics.\nKey Responsibilities\nTeam Leadership\nLead and mentor a team of scientists performing in vitro biological screening and NGS-based characterization of oligonucleotide therapeutics.\nSet team priorities, coordinate workloads, and ensure timely, high-quality delivery against corporate milestones.\nFoster a collaborative, growth-oriented team culture with a focus on scientific rigor and operational excellence.\nAssay Development & Optimization\nDesign, develop, and optimize end-to-end molecular biology and NGS workflows, including amplicon-seq and RNA-seq.\nEstablish and maintain robust high-throughput cell-based assay platforms in 96- and 384-well formats, including transfection protocols.\nApply systematic troubleshooting approaches to resolve technical challenges and continuously improve assay performance.\n Automation & Technology Integration\nLead the design, troubleshooting, and qualification of automated liquid handling workflows to maximize throughput and reproducibility.\nEvaluate and implement new instrumentation and technologies to enhance the capabilities of the HTS-NGS platform, eventually developing a fully automated system.\nOversee QC instrumentation usage and data integrity across the team (Qubit, TapeStation, Fragment Analyzer).\nCross-Functional Collaboration\nPartner closely with Chemistry, Data Science, and Biology teams to align assay outputs with downstream analytical needs and project objectives.\nCommunicate results clearly and proactively to stakeholders across functions, including through written reports and presentations.\nOperational & Data Management\nChampion LIMS adoption and data quality standards using Benchling.\nUtilize project management tools (e.g. Jira / Confluence) to track progress, manage timelines, and communicate status.\nRequired Qualifications\nPhD with 4+ years, MS with 12+ years or equivalent industry experience in cell biology, molecular biology, genomics, or a related field.\nPrior experience in a biotech or pharmaceutical environment is required.\nDemonstrated track record of managing scientists to achieve research and operational goals.\nHands-on expertise with cell culture in 96- and 384-well formats, including transfection methodologies.\nComprehensive end-to-end NGS experience: amplicon-seq, RNA-seq, library preparation, QC, and sequencing run execution.\nExpertise with Illumina sequencing platforms preferred (MiSeq).\nExpertise in core molecular biology techniques: RNA/DNA isolation, PCR/qPCR, and gel electrophoresis.\nExperience with liquid handling automation systems, including Viaflo 96/384, HiRes/Certus Flex, and/or Tempest.\nLIMS experience, preferably with Benchling.\nExceptional attention to detail and commitment to data quality and scientific reproducibility.\nStrong written and verbal communication skills; ability to distill complex technical information for diverse audiences.\nCollaborative team player who thrives in a dynamic, cross-functional biotech environment.\nPreferred Qualifications\nExperience with project management tools such as Jira and Confluence.\nFamiliarity with QC instrumentation: Qubit, TapeStation, and Fragment Analyzer.\nExperience with screening siRNA, antisense oligonucleotides, or similar constructs a strong plus.","description_format":"text","description_chars":5350,"description_truncated":false,"requirements":{"experience_years_min":12,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Molecular Diagnostics","Drug Discovery"],"lifecycle":[{"event":"open","at":"2026-10-01T16:36:26Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 1","filings_12m":1,"filings_prev_12m":2,"green_card_filings_12m":0,"median_offered_wage_usd":142500,"route":null,"cap_exempt":false,"checked_at":"2026-10-15T11:24:14+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)"],"filings_for_role_12m":0}],"liveness":{"score":71,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.79,"p_room":0.9,"age_days":19,"expected_fill_days":37,"reasons":["conf:0","win:mid"],"computed_at":"2026-10-21T05:46:15Z"},"pay":{"stated_usd_annual":180000,"is_top_pay":true},"html_url":"https://alion.io/job/korro-bio-senior-scientist","json_url":"https://alion.io/job/korro-bio-senior-scientist.json","meta":{"generated_at":"2026-10-21T07:29:34Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":10655,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-22T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":683326},"rest":"https://alion.io/mcp/rest/get_company?id=683326"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fkorro-bio-senior-scientist"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fkorro-bio-senior-scientist"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fkorro-bio-senior-scientist"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/korro-bio-senior-scientist\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fkorro-bio-senior-scientist"}]}