{"id":2467803,"url":"https://alion.io/job/kymanox-life-science-principal-program-manager","title":"Life Science - Principal Program Manager","company":{"id":2558078,"name":"Kymanox","domain":"kymanox.com","url":"https://alion.io/company/kymanox","size_band":null,"is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Jobvite","truth_index":null},"role":"Management","role_family":"Management","seniority":"lead","employment_type":null,"work_mode":"hybrid","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["King of Prussia, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":74000,"max_usd":177000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":2531},"experience_years_min":7,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[],"status":"live","first_seen_at":"2026-10-13T19:06:21Z","employer_posted_date":"2026-10-13","last_verified_at":"2026-10-18T05:48:55Z","board_verified":true,"closed_at":null,"days_open":4,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":4},"description":"Description\nJob Description:\nIs Kymanox the right fit for you?\nYou want to make a difference and have an impact…\nYou enjoy having an influence in your day-to-day work…\nYou are motivated by working alongside a team filled with\nsubject matter experts who will help you learn and grow…\nYou wake up every day and do what you do\n… because patients deserve better.\nIf this sounds like you, you’ve come to the right place.\nThe Kymanox Program Management Office is seeking aPrincipal Program Manager with a strong technical and/or operations background in the pharmaceutical, biotechnology, or medical device industries. Ideal candidates will build on their proven past performance supporting complex product development or life cycle management programs involving drug-device combination products.\nThis position is hybrid with an average of 3+ days of week at the Kymanox office in King of Prussia, PA.\nJob Description:\nThe Principal Program Manager is the client-facing lead for a portfolio of two to five projects or one to two programs focused on drug-device combination products, and is accountable for their execution and success. The role combines program leadership with hands-on technical direction. It focuses on early-phase device design and innovation and/or on design verification (DV) and testing strategy supporting combination product Design History Files (DHFs). The Principal Program Manager also mentors and develops junior and mid-level staff and is expected to grow into direct people management within the PMO. Work may take place at client sites, at a Kymanox office, or remotely.\nProgram Leadership and Delivery\nServe as the primary point of contact and accountable lead for multiple client projects or programs.\nDevelop project plans, schedules, and overall program strategy, then drive execution to deliver on scope, schedule, and budget.\nLead core project management activities, including stakeholder and risk management, schedules, dashboards, budget tracking, meeting minutes, and client correspondence.\nBuild fit-for-purpose project management tools where standard tools fall short.\nDelegate work to internal and external teams and monitor deliverable quality and progress.\nCombination Product Technical Leadership\nAct as technical lead on smaller programs or lead technical workstreams on larger programs, as needed.\nGuide early-phase device development, including user needs, design inputs, device and technology selection, feasibility work, and design reviews through design freeze.\nPlan and oversee DV programs, including test strategy, test method development and validation, protocol and report review, and traceability from requirements to verification evidence.\nAuthor, review, and remediate DHF content and other technical documentation with minimal oversight.\nAssess client documentation and development strategies, and deliver clear, actionable recommendations for mitigating gaps.\nPeople Leadership and Development\nMentor junior and mid-level program managers and engineers and review their work before client delivery.\nCoach and develop team members, with the expectation of taking on direct reports as the PMO grows.\nOversee team capacity and project assignments in partnership with PMO leadership.\nPractice Building and Compliance\nDevelop project management best practices and drive their adoption across the company.\nCollaborate cross-functionally within Kymanox and with client organizations.\nUphold regulatory standards and model a positive compliance culture.\nAptitude and Skill Set:\nVersatile and adaptable technical skills \nAble to execute high-profile activities with minimal supervision, manages time wisely and delegates as necessary \nPositive attitude, and welcomes new challenges \nFlexible to be present at client sites and sometimes travel \nStrong professional presence and presentation skills \nExtremely detail-orientated and highly organized \nExcellent written and oral English communication skills \nComfortable providing feedback and influencing internal and external stakeholders \nEmotionally stable and can navigate challenging clients and situations \nSeasoned soft skills - high EQ and team player \nAbility to work effectively with remote team members \nTackle problems proactively \nA mindset of innovation and creativity \nProficient in hands-on lab operations and competent in GLP/ GDP \nComputer and IT savvy \nThrive in a fast-paced, growing, and dynamic work environment \nExpertly solicit and utilize subject matter expert input \nValue and understand quality \nUncompromised honesty and integrity \nEducational Background:\nMinimum bachelor's degree in natural sciences (Chemistry, Biology, or similar) or engineering (Chemical, Biomedical, or Mechanical Engineering), or related technical discipline from an accredited institution. Industry certificates in project management (e.g., PMP), six-sigma, quality, or regulatory affairs preferred but not required.\nExperience:\n10+ years in the biopharma and/or medical device industries, including 7+ years working directly on drug-device combination products (e.g., prefilled syringes, autoinjectors, pen injectors, on-body injectors, infusion pumps, nasal sprays, inhalers). Consulting or client-facing experience is preferred.\n7+ years of project or program management, including at least 3 years as the accountable lead for cross-functional device or combination product development programs. PMP certification is preferred.\n3+ years mentoring and leading others, formally or informally, including reviewing technical work, providing constructive feedback, and coaching or oversight of professional development initiatives. Direct people management experience is preferred.\nDemonstrated leadership in at least one of the following technical subject matters:Early-phase design and innovation: leading concept-through-design-freeze work, including user needs, design inputs, device selection, feasibility assessment, and design reviews.\nDesign Verification and Device Testing Management: planning and managing design verification programs, test method development and validation, testing protocol and report authorship, traceability matrices, and DHF compilation or remediation. \n\nWorking knowledge of combination product and design control requirements. This includes 21 CFR Part 4, FDA’s Quality Management System Regulation (21 CFR Park 820 / ISO 13485), ISO 14971, and relevant device standards such as ISO 11608 and ISO 11040.\nSignificant contributions to complex, multi-disciplinary development programs, pharmaceutical (drug product) development, in vitro diagnostic development, clinical development, or medical device/electromechanical systems development is desirable. \nRegion:\nKing of Prussia, PA\nTravel:\nTravel may be necessary to support client work. Periodic visits (e.g. 1-2 visits per year) to other Kymanox office(s) are required.\nCareer Development:\nThe position will evolve over time and more responsibilities may be added. Since Kymanox is a growing company, there are opportunities for advancement both within the currently defined role and in other functions within the organization.\nCompensation:\nBase salary is commensurate with experience, qualifications, and other intangibles evident during the interview process - as well as market conditions. Eligible for incentive program after 6 months of outstanding work.\nBenefits:\nMedical healthcare including dental and vision, short- and long-term disability, life insurance, matching 401(k) retirement plan, continuing education assistance, and other benefits.\nAbout Kymanox:\nJoin Kymanox - a life sciences professional services company dedicated to life sciences who has successfully delivered over 4000 projects across 20+ countries. Become a member of a dynamic, fulfilling team that helps a broad range of life science products get to market more quickly, more affordably, and with the highest quality and safety standards possible in today’s biotechnology, pharmaceutical, medical device, and combination product industries. With a reputation of providing unparalleled professional services and our highly collaborative team of engineering, compliance, and project management experts, Kymanox provides an outstanding opportunity for learning and career advancement. Kymanox encourages team members, especially new graduates, and young professionals, to work on a variety of projects to gain increased learnings in Kymanox’s service offerings and the life science industry as a whole.\nKymanox is looking for motivated individuals who want to solve problems in the life science industries while doing the work they love and helping get modern medicines that enhance and save patient lives to market. Kymanox provides professional services related to engineering, compliance, and project management. We service clients ranging from Fortune 100 companies to virtual start-up companies. The company was founded in 2004 and has been growing steadily since its inception. Our corporate HQ is based in Research Triangle Park, NC.\nTo learn more about our company, please visit our website: Life Science Solutions | Kymanox\n\nKymanox is an equal-opportunity employer and works diligently to protect the rights of job seekers by following all local, state, and federal laws as well as best Human Resource (HR) practices in the Life Science industry.","description_format":"text","description_chars":9313,"description_truncated":false,"requirements":{"experience_years_min":7,"management_years_min":3,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[{"language":"English","level":"Upper-Intermediate (B2)","optional":false}]},"benefits":["Education assistance","Life insurance","Professional development","Retirement plans"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Biotechnology"],"lifecycle":[{"event":"open","at":"2026-10-13T19:06:21Z"}],"visa":[],"liveness":{"score":86,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.86,"p_room":1,"age_days":3,"expected_fill_days":26,"reasons":["conf:2","win:early"],"computed_at":"2026-10-17T05:46:00Z"},"pay":null,"html_url":"https://alion.io/job/kymanox-life-science-principal-program-manager","json_url":"https://alion.io/job/kymanox-life-science-principal-program-manager.json","meta":{"generated_at":"2026-10-18T07:36:07Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":11325,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-19T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":2558078},"rest":"https://alion.io/mcp/rest/get_company?id=2558078"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fkymanox-life-science-principal-program-manager"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fkymanox-life-science-principal-program-manager"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fkymanox-life-science-principal-program-manager"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/kymanox-life-science-principal-program-manager\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fkymanox-life-science-principal-program-manager"}]}