{"id":3123070,"url":"https://alion.io/job/kymeratx-associate-director-analytical-development","title":"Associate Director, Analytical Development","company":{"id":1988069,"name":"KymeraTx","domain":"kymeratx.com","url":"https://alion.io/company/kymeratx","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":{"grade":"B","score":83,"open_postings":6,"ghost_share":0,"stale_share":0.667,"repost_share":0,"time_to_fill_p50_days":49,"computed_at":"2026-10-23T05:54:15Z"}},"role":"Biotech","role_family":"Biotech","seniority":"head","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Watertown, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":null,"experience_years_min":10,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"GLP","optional":false},{"name":"GMP","optional":false},{"name":"HPLC","optional":false}],"status":"live","first_seen_at":"2026-08-19T18:08:03Z","employer_posted_date":"2026-10-14","last_verified_at":"2026-10-23T23:55:43Z","board_verified":true,"closed_at":null,"days_open":65,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":65},"description":"Who we are:\nKymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn. \nHow we work:\nPIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.\nCOLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.\nBELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.\nHow you’ll make an impact:\nAs the Associate Director, Analytical Development, you will contribute to CMC activities supporting mid and late phase clinical development of Kymera’s small-molecule protein degraders. You will use your scientific expertise to support CMC analytical development activities, in partnership with CDMOs.\nExecute development and validation of critical analytical methods, including achiral and chiral HPLC, GC, IC, dissolution, and methods for quantification of potentially mutagenic impurities (PMIs) and nitrosamine impurities\nEnsure analytical methods, control strategies, and specifications are robust and validated to support late stage activities from Phase 3 to commercial readiness\nPartner with CMC scientist to understand and characterize drug substance and drug product-related impurities, including impurity formation and purging, and critically review analytical testing results\nDesign and monitor ICH stability programs for drug substance and drug product\nManage day-to-day analytical development and testing activities at CDMOs and contract test labs to ensure that projects remain on track\nContribute to implementing and operating analytical capabilities in Kymera’s internal lab\nPartner closely with CMC colleagues and QA to prepare and review GMP documentation, analytical data and technical reports, and support investigation of nonconformances (OOS/OOT results, deviations, etc.)\nParticipate in authoring and reviewing analytical sections of late phase regulatory submissions (e.g., IND, IMPD, NDA, MAA).\nSupport health authority interactions, including responses to agency questions related to analytical methods and controls.\nEnsure analytical approaches meet global regulatory expectations and inspection readiness standards\nSkills and experience you’ll bring:\nPhD in Analytical Chemistry or related life sciences field is preferred, but not required, with 10+ years of experience in CMC analytical development of small molecule drug substance and oral solid dosage forms\nExperience in developing impurity control strategies, including potentially mutagenic impurities (PMIs) and nitrosamine impurities\nIn-depth expertise in late phase test method development, method validation/transfer, and characterization of small-molecule drugs\nBroad analytics expertise with widely employed techniques - HPLC (UV, RID, ELSD, CAD), GC, MS, NMR, XRPD, DSC/TGA, KF, particle size analysis, and dissolution\nKnowledgeable of compendial testing methods (USP/EP) used for DS and DP testing\nCapable of designing, implementing, and managing cGMP stability studies for DS and DP at external labs\nStrong working knowledge of GLP, cGMP, and ICH requirements\nPrior experience writing analytical sections in NDA/MAA filings a plus\nExperience working cross-functionally among project teams, including internal groups and external CDMOs\nScientific curiosity, problem-solving mindset, highly organized and detail-oriented, and excellent oral and written communication skills\n\nEqual Employment Opportunity\nKymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.\nCompensation\nKymera offers a competitive compensation package that recognizes both results and capabilities through market-based, performance-driven pay.\nThe anticipated base salary range for this role is $160,000 - $240,000, with eligibility for annual bonus, equity participation, and comprehensive benefits.\nActual salary is based on a holistic evaluation of the specific role/level as well as each candidate’s depth of experience and the capabilities they bring to the position.","description_format":"text","description_chars":5231,"description_truncated":false,"requirements":{"experience_years_min":10,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":["Equity"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Drug Discovery"],"lifecycle":[{"event":"open","at":"2026-10-23T01:17:01Z"}],"visa":[],"liveness":{"score":29,"band":"fade","label":"Fading","p_open":1,"p_active":0.664,"p_room":0.44,"age_days":64,"expected_fill_days":49,"reasons":["conf:0","win:tail","crowd:"],"computed_at":"2026-10-23T05:54:15Z"},"pay":null,"html_url":"https://alion.io/job/kymeratx-associate-director-analytical-development","json_url":"https://alion.io/job/kymeratx-associate-director-analytical-development.json","meta":{"generated_at":"2026-10-24T01:00:48Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"assistant_verified","counted_by":"address","units_charged":1,"used_today":151,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-25T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":1988069},"rest":"https://alion.io/mcp/rest/get_company?id=1988069"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fkymeratx-associate-director-analytical-development"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fkymeratx-associate-director-analytical-development"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fkymeratx-associate-director-analytical-development"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/kymeratx-associate-director-analytical-development\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fkymeratx-associate-director-analytical-development"}]}