{"id":3508471,"url":"https://alion.io/job/latchbio-ai-biologist-drug-development","title":"AI Biologist - Drug Development","company":{"id":171847,"name":"LatchBio","domain":"latch.bio","url":"https://alion.io/company/latchbio","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Ashby","truth_index":{"grade":"B","score":75,"open_postings":6,"ghost_share":0,"stale_share":1,"repost_share":0,"time_to_fill_p50_days":null,"computed_at":"2026-10-31T05:58:55Z"}},"role":"Science & Research","role_family":"Science & Research","seniority":"middle","employment_type":"full_time","work_mode":"hybrid","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["San Francisco, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":103000,"max_usd":208000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":615},"experience_years_min":3,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"AI Agents","optional":false},{"name":"GLP","optional":false},{"name":"Multimodal AI","optional":false},{"name":"Slack","optional":false}],"status":"live","first_seen_at":"2026-10-30T04:47:46Z","employer_posted_date":"2026-10-30","last_verified_at":"2026-11-01T01:28:58Z","board_verified":true,"closed_at":null,"days_open":1,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":1},"description":"AI Biologist - Drug Development\nLatch builds rigorous scientific benchmarks (benchmarks.bio) for AI agents across biology. We work with frontier labs and pharma to measure whether agents can handle real biological workflows: the messy, multi-layer reasoning that matters in the field.\nWe're seeking an AI Biologist - Drug Development to join our team working at the frontier of what artificial intelligence can achieve in drug discovery and development.\nAbout the Role\nYou will contribute to our technical approach for evaluating agent performance at reasoning across the drug discovery and development pipeline, from target validation through IND-enabling studies, and translating preclinical data into the decisions that advance (or kill) a program.\nYou will work as part of a team of software engineers and scientists building datasets and AI agent tasks across the end-to-end drug development pipeline, including:\nDesigning realistic program case studies spanning target validation, lead optimization, candidate nomination, and IND-enabling studies across modalities\n\nCurating multi-modal preclinical data bundles: SAR/potency panels, ADME/PK profiles, in vivo efficacy, GLP toxicology, safety pharmacology, and biodistribution data\n\nEvaluating PK/PD, GLP toxicology, and safety pharmacology findings across modalities and development stages\n\nReconstructing program go/no-go decisions from multi-source data\n\nReviewing and stress-testing agent outputs for pharmacological soundness, catching reasoning that is textbook-correct but not defensible in a program review\n\nCalibrating AI agent confidence on preclinical data with incomplete or conflicting signals, rather than forcing a binary call\n\nRequirements\nAdvanced degree (MS/PhD/PharmD) in pharmacology, toxicology, pharmaceutical sciences, medicinal chemistry, or a related biomedical field, or equivalent industry experience\n\n3+ years of hands-on experience in pharma or biotech drug discovery/development\n\nDirect experience with lead optimization, candidate nomination, or IND-enabling study design in at least one modality\n\nExperience interpreting PK/PD, ADME, and GLP toxicology data to inform dose selection and risk assessment\n\nFamiliarity with IND-enabling regulatory requirements and the nonclinical data package expected by FDA/EMA is s plus\n\nWorking knowledge of core pharmacology/tox study types: GLP tox, safety pharmacology, genotoxicity, biodistribution, bioanalytical assays\n\nExperience evaluating SAR, potency, selectivity, and developability trade-offs across candidate molecules\n\nStrong scientific writing skills, able to produce clear, evidence-supported rationale for a drug development decision\n\nProficiency in AI agent use, with the judgment to identify where model reasoning is technically correct but pharmacologically or practically unsound\n\nComfort operating in uncertainty, and proactively flagging gaps in data or instructions\n\nWorks with high agency and initiative\n\nCulture @ Latch\nHow we work. We practice radical transparency: you’ll know how the company is doing, what’s working, and what isn’t. It’s always us against the problem, never each other. We’re respectfully opinionated, we respect each other’s time, and we think through possible solutions before we bring a problem to anyone. Most of the team arrives between 7 and 10am and leaves between 4 and 7pm. Nobody tracks when you’re in, but we give each other a heads-up on Slack when we’re running later than usual. We judge output, not time in a seat, and the only fixed meeting are a few pod check-ins per week. We use AI constantly, so we reward original expert judgment, not AI output passed off as your own. You’ll start on the bench that fits your expertise and can move across teams as you build a track record.\nOutside of work. Company outings most months, team offsites, and a community that does cycling, soccer, figure skating, boxing, running, martial arts, music, books, and game nights.\nCompensation & Logistics (US)\nPay: $140K-$180K OTE, a mix of base & uncapped performance pay. Split varies by state.\nPerformance pay is based on weekly quota attainment.\n\nIf we pull you onto a special project, you’re paid full OTE for its duration.\n\nIf the platform goes down, you’re paid full OTE for that day.\n\nRamp: full OTE for your first 4 weeks while we onboard you into our workflows.\n\nEmployment: full-time W-2\nHealth, dental, vision: 100% covered for you, 50% for dependents\n\n401(k) (no match)\n\nPTO: 12 days to start, more as you’re promoted\n\nEquity\n\nGrowth: promotions are based on output, not tenure, with OTE rising at each level.\n\nLocation: remote, hybrid, or onsite in SF. Onsite is preferred: waterfront office in Mission Bay, catered lunch and dinner, unlimited snacks.\n\nWork authorization: we sponsor H-1B (incl. transfers), O-1, TN, and support STEM OPT.\n\nInterview Process\nTimeline: We move fast: no longer than 2 week interview process\nApply\n\nTake-Home Project - HackerRank\n\nLatch Intro - Talent Team\n\nTechnical Interview - Member of Technical Staff\n\nCulture Interview - C-Suite\n\nOffer\n\nBackground Check","description_format":"text","description_chars":5070,"description_truncated":false,"requirements":{"experience_years_min":3,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":["Equity"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Drug Discovery","Bioinformatics","Scientific & Lab Software"],"lifecycle":[{"event":"open","at":"2026-10-30T06:23:19Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 5","filings_12m":5,"filings_prev_12m":1,"green_card_filings_12m":0,"median_offered_wage_usd":112500,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)"],"filings_for_role_12m":0}],"liveness":{"score":90,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.903,"p_room":1,"age_days":1,"expected_fill_days":30,"reasons":["conf:2","velocity","win:early"],"computed_at":"2026-10-31T05:58:55Z"},"pay":null,"html_url":"https://alion.io/job/latchbio-ai-biologist-drug-development","json_url":"https://alion.io/job/latchbio-ai-biologist-drug-development.json","meta":{"generated_at":"2026-11-01T03:47:08Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":5904,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-02T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":171847},"rest":"https://alion.io/mcp/rest/get_company?id=171847"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Flatchbio-ai-biologist-drug-development"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Flatchbio-ai-biologist-drug-development"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Flatchbio-ai-biologist-drug-development"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/latchbio-ai-biologist-drug-development\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Flatchbio-ai-biologist-drug-development"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3508471}},{"tool":"search_jobs","arguments":{"company":"latch.bio","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3508471},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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