{"id":4097768,"url":"https://alion.io/job/legend-biotech-executive-director-global-program-leader","title":"Executive Director, Global Program Leader","company":{"id":12179,"name":"Legend Biotech","domain":"legendbiotech.com","url":"https://alion.io/company/legend-biotech","size_band":"1001-5000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":{"grade":"A","score":92,"open_postings":3,"ghost_share":0,"stale_share":0.333,"repost_share":0,"time_to_fill_p50_days":56,"computed_at":"2026-11-12T10:38:37Z"}},"role":"Management","role_family":"Management","seniority":"head","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"explicit","locations":["Somerset, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":256073,"max":336097,"currency":"USD","period":"year","gross":null,"usd_annual":336097},"salary_estimate":null,"experience_years_min":10,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[],"status":"live","first_seen_at":"2026-08-20T20:53:44Z","employer_posted_date":"2026-11-06","last_verified_at":"2026-11-12T20:53:42Z","board_verified":true,"closed_at":null,"days_open":84,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":84},"description":"Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting-edge therapies for patients worldwide.\nLegend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.\nLegend Biotech is seeking an Executive Director, Global Program Leader as part of the Research & Development team based inSomerset, NJ.\nRole Overview\nThe Executive Director, Global Program Leader (GPL) is a senior strategic leadership role responsible for the overall development, execution, and governance of Legend Biotech's in \nvivo CAR-T programs.\nReporting directly to the President of R&D, the GPL serves as the single point of accountability for leading cross-functional teams to define and execute integrated global development strategies from IND enabling through clinical proof-of-concept, late-stage \ndevelopment, registration, and lifecycle management. The GPL ensures alignment of program strategy, timelines, resources, and operational execution across Research, Clinical Development, Regulatory Affairs, Translational Sciences, Technical Development, Manufacturing, Commercial, Business Development, and other key functions.\nThe successful candidate will combine strong scientific and clinical development expertise with exceptional leadership, strategic thinking, and execution capabilities to advance innovative in vivo CAR-T therapies for patients worldwide.\nKey Responsibilities\nLead the overall strategy and execution of assigned in vivo CAR-T programs across the development lifecycle.\nDevelop and maintain integrated global development plans that align scientific, clinical, regulatory, manufacturing, and commercial objectives.\nServe as the primary strategic leader and accountable executive for program success, key deliverables, timelines, budgets, and milestones.\nDrive portfolio decision-making by evaluating benefit-risk profiles, competitive landscapes, development options, and investment priorities.\nEnsure alignment of program strategies with corporate objectives and portfolio priorities.\nLead the formulation and execution of global clinical development and registration strategies for in vivo CAR-T assets.\nPartner closely with Clinical Development and Regulatory Affairs to design efficient development pathways that maximize speed to proof-of-concept, pivotal development, and global approvals.\nGuide critical regulatory interactions and major health authority milestones.\nEnsure readiness and alignment for INDs, CTAs, BLA/MAA submissions, and lifecycle management activities.\nChair Global Program Teams and provide leadership across all functional areas involved in program execution.\nFoster effective collaboration among Research, Translational Medicine, Clinical Development, Regulatory Affairs, Biometrics, CMC, Quality, Manufacturing, Commercial, Finance, and Business Development.\nDrive cross-functional problem-solving and ensure timely resolution of strategic and operational risks.\nEstablish clear governance processes, decision frameworks, and accountability mechanisms.\nPresent program strategies, risks, and recommendations to executive leadership and governance committees.\nLead preparation of development scenarios, investment analyses, milestone recommendations, and portfolio reviews.\nProvide regular updates to senior management on program status, emerging opportunities, and critical risks.\nEnsure effective risk management and contingency planning throughout .\nRepresent Legend Biotech in interactions with external partners, collaborators, investigators, key opinion leaders, and other stakeholders.\nSupport business development assessments, diligence activities, and partnership opportunities related to in vivo CAR-T technologies.\nServe as a scientific and strategic ambassador for Legend’s in vivo CAR-T platform development.\nBuild a high-performance, patient-focused, and collaborative program culture.\nMentor and develop program management and cross-functional team members.\nChampion innovation, accountability, and operational excellence across development teams.\nRequirements\nMinimum 10+ years of biotechnology or pharmaceutical industry experience in drug development.\nMinimum 5+ years of leadership experience managing complex, global development programs.\nDemonstrated success advancing biologics, cell therapies, gene therapies, or other advanced therapeutic programs through clinical development.\nDirect experience leading cross-functional development teams in a matrix environment.\nExperience supporting global regulatory interactions and major regulatory submissions.\nExperience in oncology, immunology, cell therapy, gene therapy, or in vivo genetic medicines strongly preferred.\nDeep understanding of global drug development, clinical development, and registration pathways.\nStrong knowledge of cell and gene therapy development, including emerging in vivo CAR-T technologies.\nExceptional strategic thinking and portfolio management capabilities.\nDemonstrated ability to influence senior leaders and drive decisions in complex environments.\nOutstanding communication, presentation, and executive stakeholder management skills.\nStrong business acumen, financial awareness, and risk-management capabilities.\nProven ability to lead diverse global teams and achieve ambitious development goals.\nAbility to operate effectively in a dynamic, fast-paced biotechnology environment.\nThe base pay range below is what Legend Biotech USA Inc. reasonably expects to offer at the time of posting. Actual compensation may vary based on experience, skills, qualifications, and geographic location. The company reserves the right to modify this range as needed and in accordance with applicable laws.\nOther Types of Pay: Performance-based bonus and/or equity is available to employees in eligible roles.\nBenefits and Paid Time Off: Medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one. We offer eight (8) weeks of paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and eleven (11) company holidays. Additional voluntary benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide voluntary commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.\nPay Range (Base Pay):\n$256,073—$336,097 USD\nPlease note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.\nWork Authorization & Employment Eligibility\nApplicants must be authorized to work in the United States. As part of our commitment to maintaining a lawful workforce and ensuring compliance with federal employment regulations, we participate in the E-Verify program. If you are selected for employment, you will be required to complete the Form I-9 process, and your employment eligibility will be verified through E-Verify in accordance with applicable federal law. We are committed to providing a fair, transparent, and welcoming hiring experience for all candidates.\nEEO Statement\nIt is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.\nEmployment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.\nFor information related to our privacy notice, please review: Legend Biotech Privacy Notice.","description_format":"text","description_chars":9103,"description_truncated":false,"requirements":{"experience_years_min":10,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":null,"security_clearance":false,"languages":[]},"benefits":["Equity","Parental leave","Retirement plans","Vision insurance"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Cell & Gene Therapy","Oncology Therapeutics"],"lifecycle":[{"event":"open","at":"2026-11-11T21:18:00Z"}],"visa":[{"country":"US","licensed_sponsor":true,"adverts_offering_sponsorship_24m":0,"sanctioned_now":false,"evidence":"H-1B filings in 12 months: 26 · green card filings: 3","filings_12m":26,"filings_prev_12m":27,"green_card_filings_12m":3,"median_offered_wage_usd":116466,"route":null,"cap_exempt":false,"checked_at":"2026-11-12T07:36:15+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":35,"band":"fade","label":"Fading","p_open":1,"p_active":0.787,"p_room":0.44,"age_days":83,"expected_fill_days":56,"reasons":["conf:2","win:tail","crowd:"],"computed_at":"2026-11-12T10:38:37Z"},"pay":{"stated_usd_annual":336097,"is_top_pay":true},"html_url":"https://alion.io/job/legend-biotech-executive-director-global-program-leader","json_url":"https://alion.io/job/legend-biotech-executive-director-global-program-leader.json","meta":{"generated_at":"2026-11-13T02:45:23Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":5852,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-14T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.1,"usd":0.01,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":12179},"rest":"https://alion.io/mcp/rest/get_company?id=12179"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Flegend-biotech-executive-director-global-program-leader"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"free","price":{"credits":0,"usd":0},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Flegend-biotech-executive-director-global-program-leader"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.1,"usd":0.01},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Flegend-biotech-executive-director-global-program-leader"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/legend-biotech-executive-director-global-program-leader\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Flegend-biotech-executive-director-global-program-leader"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":4097768}},{"tool":"search_jobs","arguments":{"company":"legendbiotech.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":4097768},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. Docs: https://alion.io/developers"}}