{"id":1420691,"url":"https://alion.io/job/legend-biotech-senior-scientist-analytical-development-ffba","title":"Senior Scientist, Analytical Development (FFBA)","company":{"id":12179,"name":"Legend Biotech","domain":"legendbiotech.com","url":"https://alion.io/company/legend-biotech","size_band":"501-1000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":"senior","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"explicit","locations":["Somerset, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":127313,"max":167099,"currency":"USD","period":"year","gross":null,"usd_annual":167099},"salary_estimate":null,"experience_years_min":8,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Power BI","optional":true}],"status":"live","first_seen_at":"2026-09-28T16:17:23Z","employer_posted_date":"2026-10-01","last_verified_at":"2026-10-20T10:17:02Z","board_verified":true,"closed_at":null,"days_open":21,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":21},"description":"Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting-edge therapies for patients worldwide.\nLegend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.\nLegend Biotech is seeking a Senior Scientist, Analytical Development (FFBA) as part of the Technical Development team based in Somerset, NJ.\nRole Overview\nWe are seeking a dynamic and scientifically driven Senior Scientist to join our empowered Analytical Development organization. This role will focus on the establishment, development and qualification of analytical assays, including but not limited to flow cytometry-based methods, cell culture-based methods, immunoassays, compendial methods, and other bioanalytical strategies to support the development and manufacturing of Legend’s pipelines. The ideal candidate will be a hands-on leading scientist, capable of mentoring junior scientists while also contributing strategically to cross-functional collaborations with other functional teams, and deeply understanding of GxP requirement.\nKey Responsibilities\nDevelop, optimize, and execute analytical methods to support cell and gene therapy product releasing and characterization, including but not limited to compendial methods, titer, particle size, flow cytometry, cell-based potency or functional methods, and bioanalytical (e.g., ELISA) assays.\nGuide method development activities to support phase-appropriate analytical deliverables (including potency, purity, safety, etc.) with an emphasis on scientific rigor, data integrity, and patient-centricity.\nDrive the timely tech transfer of assays from collaborators to AD, and/or from AD to QC and external collaborators.\nIdentify and refine critical parameters and material/reagents during assay prequalification activities; generate and qualify critical materials including but not limited to cell banks.\nDrive the development and qualification of release assays for early-phase clinical programs, and ensure execution on aggressive timelines.\nAuthor and review analytical related documentation including but not limited to analytical methods, SOPs, protocols, and reports.\nPerforming pre-qualification, assay qualification, product release testing, and product stability testing in a quality control environment.\nCollaborate cross-functionally with QC, PD and Manufacturing teams to ensure seamless assay execution, troubleshooting, and continuous improvement.\nPresent scientific data and trends at internal and external forums\nEnsure proper documentation practices including lab notebooks, QC records, and equipment maintenance logs.\nBalance multiple projects while meeting established timelines.\nThis role is empowered to make independent decisions related to the planning, execution, analysis, and troubleshooting of analytical method development, qualification, transfer, and characterization activities within established project timelines and departmental objectives. The Senior Scientist is expected to exercise scientific judgment in experimental design, data interpretation, risk assessment, and the recommendation of technical solutions to complex analytical challenges. Collaboration, consensus, and alignment with management are required for decisions that may impact program strategy, regulatory submissions, project timelines, resource allocation, quality systems, or cross-functional development activities. The position is also expected to provide technical guidance to junior staff and contribute to scientific decision-making across multidisciplinary project teams.\nRequirements\nAdvanced degree (PhD or Master) in immunology, cell biology, biomedical engineering, or equivalent. 5-8 years (PhD) or 8-10 years (Master) of experience in method development of gene-modified products in analytical development and/or QC in a biotech, or pharmaceutical setting. Technical training / certification is desirable.\nUses professional concepts in accordance with company objectives to solve complex problems in creative and effective ways.\nExpertise in analytical method development and qualification is required (Vaccine, Biologics, Viral Vector, or CGT).\nSolid understanding of ICH guidelines and regulatory expectations for method development and qualification/validation.\nExpertise in analytical method development and validation in late stage is preferred.\nExperience in analytical comparability strategy, method bridging, method transfer activities for early and late phase in product development. Global experience is a plus.\nExperience in developing lentiviral vector product releasing and characterization methods including multicolor flow cytometry methods, cell culture including reporter gene cell line development, potency assays, cytotoxicity assays and cytokine release assays, immunoassays, infectious titer assays.\nExercises independent judgment in developing methods, techniques and evaluation criteria for obtaining results.\nDeep understanding and experience in analytical data trending, critical reagent and material determination and qualification, establishment of product releasing specification for early and late stage product development.\nGuide the establishing and authoring of SOPs/procedures, protocols, and reports for analytical methods and activities.\nAuthorship in IND/BLA preparation is preferred.\nDemonstrated ability to lead, mentor, and develop junior staff in a matrixed and collaborative environment.\nDetail-oriented with expertise in problem solving and solid decision-making abilities.\nExperience implementing or executing compendial methods (HPLC, Ph, Osmolality, Particulate Matter, etc) is preferred.\nExcellent presentation skills, scientific/technical writing skills, and communication skills.\nGuide the establishing and authoring of SOPs/procedures for established methods.\nExperience with:Excel, Word, PowerPoint, etc\nGraphPad Prism, other data analysis tools (PowerBI, JUMP, R)\nCytoExpert, FCS express, NovoExpress, FlowJo, etc\nELN, LabVantage, etc.\n\nLanguage(s): Strong written and verbal English skills are required. Mandarin preferred.\n AI Literacy: Possesses a working knowledge of AI technologies and approved AI tools, applies them responsibly to enhance productivity and decision-making, exercises appropriate human oversight of AI-generated outputs, and complies with organizational policies governing AI use.\nThe base pay range below is what Legend Biotech USA Inc. reasonably expects to offer at the time of posting. Actual compensation may vary based on experience, skills, qualifications, and geographic location. The company reserves the right to modify this range as needed and in accordance with applicable laws.\nOther Types of Pay: Performance-based bonus and/or equity is available to employees in eligible roles.\nBenefits and Paid Time Off: Medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one. We offer eight (8) weeks of paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and eleven (11) company holidays. Additional voluntary benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide voluntary commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.\nPay Range (Base Pay):\n$127,313—$167,099 USD\nPlease note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.\nWork Authorization & Employment Eligibility\nApplicants must be authorized to work in the United States. As part of our commitment to maintaining a lawful workforce and ensuring compliance with federal employment regulations, we participate in the E-Verify program. If you are selected for employment, you will be required to complete the Form I-9 process, and your employment eligibility will be verified through E-Verify in accordance with applicable federal law. We are committed to providing a fair, transparent, and welcoming hiring experience for all candidates.\nEEO Statement\nIt is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.\nEmployment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.\nFor information related to our privacy notice, please review: Legend Biotech Privacy Notice.","description_format":"text","description_chars":10092,"description_truncated":false,"requirements":{"experience_years_min":8,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[{"language":"English","level":"All levels","optional":false}]},"benefits":["Equity","Parental leave","Retirement plans","Vision insurance"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Cell & Gene Therapy","Oncology Therapeutics"],"lifecycle":[{"event":"open","at":"2026-09-28T22:16:38Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 26 · green card filings: 3","filings_12m":26,"filings_prev_12m":27,"green_card_filings_12m":3,"median_offered_wage_usd":116466,"route":null,"cap_exempt":false,"checked_at":"2026-10-15T11:24:14+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":76,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.849,"p_room":0.9,"age_days":21,"expected_fill_days":57,"reasons":["conf:0","win:mid"],"computed_at":"2026-10-20T05:45:00Z"},"pay":{"stated_usd_annual":167099,"is_top_pay":true},"html_url":"https://alion.io/job/legend-biotech-senior-scientist-analytical-development-ffba","json_url":"https://alion.io/job/legend-biotech-senior-scientist-analytical-development-ffba.json","meta":{"generated_at":"2026-10-20T14:17:54Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":16042,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-21T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":12179},"rest":"https://alion.io/mcp/rest/get_company?id=12179"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Flegend-biotech-senior-scientist-analytical-development-ffba"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Flegend-biotech-senior-scientist-analytical-development-ffba"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Flegend-biotech-senior-scientist-analytical-development-ffba"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/legend-biotech-senior-scientist-analytical-development-ffba\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Flegend-biotech-senior-scientist-analytical-development-ffba"}]}