{"id":812536,"url":"https://alion.io/job/locus-bio-development-technologist-or-research-technician-rotational-program","title":"Development Technologist or Research Technician, Rotational Program","company":{"id":681754,"name":"Locus Biosciences","domain":"locus-bio.com","url":"https://alion.io/company/locus-bio","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Recruitee","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":"junior","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Research Triangle Park, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":55000,"max_usd":115000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":849},"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Bioreactors","optional":false},{"name":"CAPA","optional":false},{"name":"Chromatography","optional":false},{"name":"GLP","optional":false},{"name":"GMP","optional":false},{"name":"Next-Generation Sequencing","optional":false},{"name":"Design of Experiments","optional":true},{"name":"PCR","optional":true}],"status":"live","first_seen_at":"2026-07-23T14:55:03Z","employer_posted_date":"2026-07-23","last_verified_at":"2026-11-08T08:23:23Z","board_verified":true,"closed_at":null,"days_open":107,"trust":{"level":"stale","repost_count":0,"flags":["stale"],"days_open":107},"description":"Locus Biosciences is seeking a highly motivated and entrepreneurial applicant to join our company in a full-time, entry-level position that will rotate between our Chemistry, Manufacturing and Controls (CMC) and Research & Development (R&D) departments during this 2 year rotational program. This position is well suited for those looking for an entry-level position that is excited to learn all aspects of biotechnology drug development from early-stage research through drug product manufacturing. Candidates will be expected to accomplish defined work, as well as assist in approaching and solving complex scientific problems. Candidates should have demonstrated laboratory or manufacturing experience, with solid communication, technical aptitude, and problem-solving skills. Experience working in regulated, pharmaceutical/biotechnology R&D (GDP, GLP) and/or manufacturing environments (cGMP) is strongly preferred, but not required.\nWhy Locus?\nChange the future of medicine and address a serious and unmet patient need by developing completely novel therapeutic modalities.\n\nFast-track your career by tackling large & meaningful projects and learning a breadth of techniques and skillsets in the wet lab and manufacturing suites\n\nWork with a team of exceptionally talented and hardworking individuals while striving to achieve a common mission\n\nPartner with the most highly respected pharmaceutical companies in the world\n\nBonus pool eligibility\n\nHealth, dental, vision, life insurance, 401(k), and PTO\n\nFree access to fitness center and classes\n\nResponsibilities will include:\nDesigning and/or executing formulation development activities\n\nDesigning and/or executing bench-scale process development activities, including set-up and operation of development-scale bioreactors, filter trains, tangential flow filtration (TFF) equipment, and chromatography equipment\n\nDevelopment of analytical strategies to inform formulation and process development activities\n\nDesign and deploy automated workflows for molecular biology and microbiology assays, including liquid handling automation, next-generation sequencing (NGS) library preparation, and high-throughput screening of phage activity to accelerate research timelines and improve experimental reproducibility.\n\nSupport the development of data infrastructure and bioinformatics pipeline for R&D and CMC operations, including DNA sequence analysis, sequence assembly, and comparative genomic analysis.\n\nMolecular biology and synthetic biology- Cloning, NGS library preparation, characterization of novel genetic engineering tools, and generation and analysis of novel engineered phage clones\n\nMicrobiology - Culturing both aerobic and obligate anaerobic organisms. Utilizing a range of bacterial strains to produce and characterize activity of phage\n\nIndependent management, planning, and execution of multiple projects, including reviewing, interpreting, and recording results.\n\nSupporting tech transfer of new products and processes to ensure smooth transition from R&D to process development to GMP manufacturing\n\nForming strong relationships with all stakeholders, including technicians, associates, project and program managers, and scientists to enable successful tech transfer\n\nSupporting Scientists in all aspects of pharmaceutical development\n\nAssisting in the preparation of batch records, protocols, SOPs, deviations, technical reports, presentations, and other CMC documents to support drug development, including INDs, BLAs, and other applications\n\nGaining aseptic gowning and fill qualification\n\nPerforming material handling and staging\n\nPracticing real-time documentation (such as batch records) during production run and maintain accurate records/logs according to GDP\n\nSupporting Qualification and Validation activities\n\nIdentifying, communicating, and troubleshooting process issues\n\nSupporting team effort in the effective and timely completion of root cause investigations and CAPA\n\nSupporting a high-performance teamwork environment\n\nRotations may include a combination of any of the following functions:\nResearch and Development including but not limited to phage discovery, phage engineering, and strain engineering.\n\nHigh Throughput Development (Automation)\n\nBioinformatics\n\nMaterial Sciences & Technology\n\ncGMP Manufacturing\n\nAnalytical Development\n\nQuality Control\n\nClinical Lab\n\nQuality Assurance\n\nProject Management Office\n\nClinical Operations\n\nRequirements\nEducation:\nTechnical certificate or degree (e.g. BTEC Biomanufacturing), or graduation from an accredited college/university with a Bachelor’s to a Master’s degree in Biology, Chemistry, Biochemistry, Chemical Engineering, Biophysics, Pharmaceutical Technology or related field, with some lab experience (required)\n\nExperience and Expertise:\nFamiliarity with general laboratory techniques such as pipetting, serial dilutions, aseptic technique and proper decontamination procedures\n\nExperience in research, pharmaceutical, biotechnology, and/or sterile production environment\n\nExperience executing SOPs and documenting work\n\nStrong mechanical aptitude\n\nExcellent oral and written communication skills\n\nTechnical writing ability\n\nThrives in a fast-paced, entrepreneurial and collaborative environment. Openly shares knowledge/information needed to accomplish a task or solve a problem\n\nPreferred Qualifications:\nAt least two years’ experience between academic or industry research\n\nExperience in biologics (upstream, downstream, aseptic fill/finish) with working knowledge of FDA regulations and GMP systems\n\nExperience with DNA sequence analysis, including homology searching, sequence assembly and primer design\n\nAbility to assist in the design of experiments and interpretation of results\n\nMotivation to learn new processes that contribute to the company's overall desire to get products into the clinic\n\nTechnical proficiency with designing and executing standard molecular biology experiments (PCR, transformation, Gibson cloning)\n\nExperience with microbiology skills like growth curves, anaerobic microbiology, streaking and banking strains\n\n*The level of the position will be based on the successful candidate’s qualifications.\nAbout Locus Biosciences\nLocus Biosciences is a clinical-stage biotechnology company developing precision antibacterial products to address critical unmet medical needs in treating bacterial infections and microbiome indications. The Locus platform engineers bacterial viruses called bacteriophages to specifically kill target pathogens while leaving non-target bacteria (i.e., the rest of the patient’s microbiome) unharmed and to deliver biotherapeutic payloads to the body sites where they are needed. Locus’s lead program is an engineered bacteriophage product targeting Escherichia coli bacteria in the urinary tract, currently being tested in an active Phase 2/3 clinical trial. Locus has collaborations with BARDA and CARB-X to develop engineered bacteriophage products targeting E. coli infections and Klebsiella pneumoniae infections, respectively. For more information about Locus visit https://www.locus-bio.com/\nSHIFT: Full-Time Days, with occasional evening and weekend work\nJob Type: Full-time, onsite\nJob Location: Research Triangle Park, North Carolina\nDirect applicants only. 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