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Salary
$42k – $58k per year
Location
In office (Boston)
Employment
Full-Time
Overview
Company
Impact
Profile match
Mass General Brigham is a prominent non-profit healthcare system and integrated network of hospitals and physicians originally founded by Brigham and Women's Hospital and Massachusetts General Hospital. Headquartered in Boston, Massachusetts, the organization serves as a major teaching affiliate for Harvard Medical School and conducts extensive biomedical research. Beyond its primary academic medical centers, the vast health network operates numerous community hospitals, specialty facilities, and health insurance plans to provide comprehensive patient care.
Site: Massachusetts Eye and Ear Infirmary

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

POSITION SUMMARY:

The Grousbeck Gene Therapy Center at Mass Eye and Ear has an open position for a Research Assistant to assist in the application of novel gene therapy modalities. The Center provides a dynamic multi-disciplinary environment that pursues the common goal of developing therapeutic gene transfer in future medicine.

We are seeking a Research Assistant to join the Gene Transfer Vector Core within Grousbeck Gene Therapy Center. The primary responsibilities will include AAV vector production, purification, and quality control to support preclinical research projects. Experience with molecular biology, cell culture, or viral vector production is preferred. Familiarity with standard laboratory techniques and maintaining accurate experimental records is desirable. Strong organizational skills, attention to detail, and the ability to manage multiple projects are essential. A bachelor’s degree in biology, biotechnology, molecular biology, or a related field is required.

We offer a flexible and collaborative environment, as well as the opportunity to develop scientifically and to explore the promising field of translational AAV gene therapy.

ESSENTIAL FUNCTIONS:

  • AAV vector production, purification, and formulation
  • Mammalian cell culture and transfection
  • Vector genome titration and routine quality-control assays
  • Preparation of buffers, reagents, and production materials
  • Maintenance of batch records, sample tracking, and documentation
  • General laboratory maintenance, inventory, and equipment support
  • Follow established SOPs and biosafety procedures

EDUCATION AND EXPERIENCE:

  • BS/BA in biology or related discipline
  • Experience in or willing to learn AAV production
  • Must be able to work as part of a team.
  • Excellent time management and organization.

WORKING CONDITIONS:

Work will primarily take place in a research laboratory setting. Job may require exposure to bio-hazardous or toxic substances.

Qualifications

Education

Bachelor's Degree in a related field

Candidates who are in the process of completing their bachelor's degree have a grace period of six months from their hire date (up to 1 year if starting per diem) to provide degree equivalency verification.

Can this role accept experience in lieu of a degree?

Yes

Licenses and Credentials

Experience

Prior laboratory experience, either through academic coursework, internships, or employment. 1-2 years preferred

Knowledge, Skills and Abilities

- Strong theoretical and practical knowledge of laboratory techniques and procedures.

- Familiarity with common laboratory equipment and instruments used in research experiments.

- Proficiency in data collection, analysis, and scientific software tools.

- Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.

- Strong problem-solving skills and the ability to troubleshoot technical issues.

- Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.

Additional Job Details (if applicable)

Remote Type

Onsite

Work Location

20 Staniford Street

Scheduled Weekly Hours

40

Employee Type

Regular

Work Shift

Day (United States of America)

Pay Range

$21.00 - $29.01/Hourly

Grade

5At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

EEO Statement:

5110 Massachusetts Eye and Ear Infirmary is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

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