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Mayo Clinic is the No. 1 hospital in the world., with campuses in Arizona, Florida, and Minnesota.

The Gut Microbiome Laboratory, housed within the Enteric Neurosciences Program at Mayo Clinic (Rochester, MN), is seeking a highly motivated, self-driven postdoctoral fellow to join a collaborative and translational research team focused on defining pathophysiological mechanisms underlying gastrointestinal motility disorders.

Our program represents one of the largest and most integrated groups of physicians and scientists studying the enteric nervous system and gastrointestinal physiology, with a long history of paradigm-shifting discoveries that have shaped the field. We are seeking new team members who are excited to contribute to, and extend, this distinguished tradition.

The laboratory is at the forefront of research in human neurogastrointestinal disorders, including irritable bowel syndrome (IBS). We employ an integrated experimental approach that combines physiology, advanced imaging, molecular and cellular biology, and in vivo animal models to interrogate gut-microbe-host interactions. Our work is published in high-impact journals (Gastroenterology, Cell, Cell Host & Microbe, and Science Translational Medicine) and is supported by NIH funding.

We provide extensive resources, mentorship, and a highly collaborative environment to support trainees as they advance to the next stages of their careers. We are committed to fostering a diverse, inclusive, and supportive culture, and we value community, celebrating milestones together, and creating space to recognize both scientific accomplishments and the people behind them.

Qualified candidates should hold a PhD or MD/PhD in physiology, neuroscience, molecular biology, or a related discipline and be within five years of PhD completion. This position is not intended for clinical training and is not open to MD/MBBS candidates seeking clinical roles.

Experience in advanced imaging, single-cell or spatial transcriptomics, and mouse physiological studies is highly desirable, and candidates with expertise in these areas are strongly encouraged to apply.

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