{"id":1310732,"url":"https://alion.io/job/mbxbio-clinical-scientist","title":"Clinical Scientist","company":{"id":2359299,"name":"mbxbio","domain":"mbxbio.com","url":"https://alion.io/company/mbxbio","size_band":null,"is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":"middle","employment_type":null,"work_mode":"hybrid","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Burlington, United States","Burlington, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":71000,"max_usd":146000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":638},"experience_years_min":3,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"GCP","optional":false},{"name":"GLP","optional":false}],"status":"live","first_seen_at":"2026-08-28T11:47:12Z","employer_posted_date":"2026-08-28","last_verified_at":"2026-10-23T11:33:26Z","board_verified":true,"closed_at":null,"days_open":55,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":55},"description":"Working with Us\nMBX Biosciences is a clinical-stage biopharmaceutical company headquartered in Carmel, Indiana, with a secondary office in Burlington, MA. Our mission is to transform the lives of people impacted by endocrine and metabolic disorders through our novel precision peptides.\nLeveraging our proprietary Precision Endocrine Peptides (PEPs)™ platform, we are pioneering technology designed to overcome key limitations of existing therapies and enhance efficacy, tolerability, safety and convenience. Our team is advancing a pipeline of novel candidates with clinically validated targets, established endpoints for regulatory approval, and strong market potential.\nOur pipeline includes canvuparatide (MBX 2109) for the treatment of chronic hypoparathyroidism, currently preparing for Phase 3 development, and a growing obesity portfolio that includes MBX 4291 in Phase 1 development, MBX 5765, a next-generation amycretin prodrug designed for once-monthly-dosing, as well as MBX 6180, a GLP/GIP/GCGR triple agonist prodrug for once monthly dosing; all of which optimize our PEP platform.\nIf you’re passionate about advancing innovative treatments for patients and shaping the future of precision peptide therapeutics, this is your chance to make a real impact alongside a fast-paced, growing, mission-driven team. To learn more, visit our website mbxbio.com and follow us on LinkedIn.\nWhat You’ll Do\nThe Clinical Scientist will provide clinical and scientific expertise to deliver clinical studies in early- and/or late-stage development. This individual will be responsible for the hands-on implementation and execution of assigned clinical studies under the supervision of a Director/Senior Director in Clinical Development. This individual will support clinical studies in collaboration with other members of the cross-functional study team. Clinical Pharmacology studies may be in-scope based on company need.\nProvide clinical and scientific oversight of clinical study execution, from start-up to close-out and results reporting.\nLeading role in authoring clinical study protocols/amendments and related study documents (including but not limited to drug specific risk language, ICFs, clinical study training materials, pharmacy manual, laboratory manual, etc.) by translating the strategy and approved concept into executable and efficient clinical studies.\nContribute to authoring various regulatory study documents, including clinical sections of IND/NDA and CTA submissions, investigator brochures, annual reports and updates, and clinical sections of heath authority responses.\nDevelop a clinical study execution plan in collaboration with cross-functional study leads.\nShare the responsibility for establishing and maintaining regular cross-functional study team meetings with the study Clinical Operations Lead.\nContribute to the selection and management of study vendors, including but not limited to CROs, central laboratories/imaging, clinical sites, EDC, IRT, TMF, etc.\nTrain internal and/or external study team members on medical and scientific aspects of the clinical study at SIVs and at other applicable forums.\nReview and monitor emerging clinical study data related to safety and efficacy (including but not limited to establishing the medical monitoring plan, conducting medical review, and documenting the outcome of medical review).\nWork closely with the Study Medical Lead and Director/Senior Director of Clinical Development to report clinical study progress and ensure timely communication of any identified medical or operational issues.\nProactively identify and review emerging study issues by actively engaging with study CRO, vendors, and cross-functional study leads.\nDevelop sound and strategic solutions to arising study issues and collaborate with pertinent study team members to ensure issue resolution.\nSupport the review, analysis, and interpretation of clinical study results.\nContribute to clinical study report development and ensure timely finalization.\nAs needed, present clinical study data to internal and/or external stakeholders.\nMaintain current knowledge of pertinent therapeutic area(s)\nOther responsibilities as assigned.\nWhat You Bring\nDegree in Life Sciences (PhD, PharmD, RN, NP) with at least 3 years of hands-on early- and/or late-stage clinical development experience in a pharmaceutical or biotechnology organization is required. Late-stage clinical development experience preferred.\nClinical research background in metabolic diseases is preferred.\nUnderstanding of the drug development process from pre-IND through registration.\nUnderstanding of drug development functional areas, including preclinical, clinical pharmacology, regulatory, pharmacovigilance, drug supply, biometrics (data management, biostatistics, programming), and clinical operations.\nAbility to understand, interpret, and communicate clinical information including clinical study data, literature reviews, and current treatment practices to inform decision-making and clinical strategy.\nCandidates must possess effective communication and influencing skills across functions.\nCritical traits for success include strategic and proactive thinking, strong scientific and analytical skills, decisiveness and the ability to perform as a respected team member.\nAbility to work effectively in a collaborative and highly matrixed team environment where results are achieved through influence, cooperation, and the incorporation of multiple points of view.\nIndependently motivated, detail oriented, and good problem-solving ability.\nExcellent organizational skills, with an ability to embrace change and multi-task in an extremely fast-paced environment.\nProficient knowledge of GCP/ICH.\nProficient in Microsoft Word, Excel, PowerPoint, Electronic Data Capture.\nTravel & In Office Presence \nYou will be expected to travel periodically based on the needs of the business, including attendance at Together Weeks, Together Days, and functional meetings as requested by the team. Employees are expected to work on hybrid schedules, consistent with local office practices and the terms of the companies in office policy as in effect from time to time.\nEEO Statement: \nMBX Biosciences is an Equal Opportunity Employer and is committed to treating all applicants fairly without discrimination. We welcome applications from all individuals, regardless of race, national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, pregnancy, sexual orientation, gender identity, gender expression or any unlawful criterion under applicable law.","description_format":"text","description_chars":6622,"description_truncated":false,"requirements":{"experience_years_min":3,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Biotechnology","Health Care","Science & Engineering","CRO & CDMO Services"],"lifecycle":[{"event":"open","at":"2026-09-26T15:59:14Z"}],"visa":[],"liveness":{"score":53,"band":"ok","label":"Likely open","p_open":1,"p_active":0.702,"p_room":0.75,"age_days":55,"expected_fill_days":63,"reasons":["conf:3","win:late"],"computed_at":"2026-10-23T05:54:15Z"},"pay":null,"html_url":"https://alion.io/job/mbxbio-clinical-scientist","json_url":"https://alion.io/job/mbxbio-clinical-scientist.json","meta":{"generated_at":"2026-10-23T11:45:00Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":17780,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-24T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":2359299},"rest":"https://alion.io/mcp/rest/get_company?id=2359299"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fmbxbio-clinical-scientist"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fmbxbio-clinical-scientist"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fmbxbio-clinical-scientist"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/mbxbio-clinical-scientist\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fmbxbio-clinical-scientist"}]}