Payroll Specialist
Confirmed on the employer's own hiring board on Oct 24, 2026. First seen by Alion on Oct 22, 2026.
Working with Us
MBX Biosciences is a clinical-stage biopharmaceutical company headquartered in Carmel, Indiana, with a secondary office in Burlington, MA. Our mission is to transform the lives of people impacted by endocrine and metabolic disorders through our novel precision peptides.
Leveraging our proprietary Precision Endocrine Peptides (PEPs)™ platform, we are pioneering technology designed to overcome key limitations of existing therapies and enhance efficacy, tolerability, safety and convenience. Our team is advancing a pipeline of novel candidates with clinically validated targets, established endpoints for regulatory approval, and strong market potential.
Our pipeline includes canvuparatide (MBX 2109) for the treatment of chronic hypoparathyroidism, currently preparing for Phase 3 development, and a growing obesity portfolio that includes MBX 4291 in Phase 1 development, MBX 5765, a next-generation amycretin prodrug designed for once-monthly-dosing, as well as MBX 6180, a GLP/GIP/GCGR triple agonist prodrug for once monthly dosing; all of which optimize our PEP platform.
If you’re passionate about advancing innovative treatments for patients and shaping the future of precision peptide therapeutics, this is your chance to make a real impact alongside a fast-paced, growing, mission-driven team. To learn more, visit our website mbxbio.com and follow us on LinkedIn.
What You’ll Do
MBX Biosciences is seeking a Payroll Specialist to be responsible for timely and accurate payroll processing and related tax reporting for MBX Biosciences. Key responsibilities will include handling payroll functions, including handling semi-monthly payroll preparation, managing deductions, and addressing any payroll-related inquiries. You will also take responsibility for all payroll tax jurisdiction maintenance and correspondence. Communication, organizational skills, and attention to detail, as well as the ability to multi-task, are key to successful incumbents consistently functioning at the highest level with the utmost regard for the MBX’s mission & values. A proactive attitude and a problem-solving mindset are vital for thriving in this dynamic environment.
Including but not limited to:
- Assist in the preparation of multi-state semi-monthly payroll
- Prepare semi-monthly payroll journal entries and assist with monthly/quarterly payroll reconciliations.
- Responsible for maintaining up-to-date registrations for all applicable state and local tax jurisdictions and any related correspondence with jurisdictions
- Coordinate with Human Resources on payroll matters related to new hires, terminations, changes in salary, tax withholdings, deductions, benefit changes, leave of absences and any other employee pay changes
- Verify, remit and finalize the transmission of employee deductions for 401(k) and HSA to our respective plan provider.
- Process equity related compensation accurately for W-2 purposes, as applicable
- Maintain files and documentation thoroughly and accurately, in accordance with company policy, generally accepted accounting policies and Sarbanes Oxley (SOX)
- Support year-end IRS form reporting process, including verifying accuracy of employee W-2s and supporting preparation of Form 3921s and Form 3922s.
- Supports Controllership/Finance department on miscellaneous/ad-hoc projects.
- Other responsibilities as assigned
What You Bring
- 3+ years of experience in payroll processing in multi-state environments
- Bachelor’s degree; major in Business related field preferred
- Extensive knowledge or state specific payroll tax and experience managing multiple state registrations and ongoing compliance
- Experience processing equity related payroll information (i.e. NQSO, ISO’s, RSU, disqualifying dispositions) in coordination with a captive broker
- Experience in a company subject to SOX compliance
- Proficiency with Paycor & NetSuite a plus
- Very detail-oriented and well organized
- Ability to work independently in a fast-paced environment and handle multiple projects at once
Travel
You will be expected to travel periodically based on the needs of the business to the extent requested by the Company including attendance at Together Weeks, Together Days and functional meetings as requested by the Company.
Company Overview:
MBX Biosciences is a clinical-stage biopharmaceutical company headquartered in Carmel, Indiana, with a secondary office in Burlington, MA. Our mission is to transform the lives of people impacted by endocrine and metabolic disorders through our novel precision peptides.
Leveraging our proprietary Precision Endocrine Peptides (PEPs)™ platform, we are pioneering technology designed to overcome key limitations of existing therapies and enhance efficacy, tolerability, safety and convenience. Our team is advancing a pipeline of novel candidates with clinically validated targets, established endpoints for regulatory approval, and strong market potential.
Our pipeline includes canvuparatide (MBX 2109) for the treatment of chronic hypoparathyroidism, currently preparing for Phase 3 development, and a growing obesity portfolio that includes MBX 4291 in Phase 1 development, MBX 5765, a next-generation amycretin prodrug designed for once-monthly-dosing, as well as MBX 6180, a GLP/GIP/GCGR triple agonist prodrug for once monthly dosing; all of which optimize our PEP platform.
If you’re passionate about advancing innovative treatments for patients and shaping the future of precision peptide therapeutics, this is your chance to make a real impact alongside a fast-paced, growing, mission-driven team. To learn more, visit our website mbxbio.com and follow us on LinkedIn
EEO Statement:
MBX Biosciences is an Equal Opportunity Employer and is committed to treating all applicants fairly without discrimination. We welcome applications from all individuals, regardless of race, national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, pregnancy, sexual orientation, gender identity, gender expression or any unlawful criterion under applicable law.