{"id":1396025,"url":"https://alion.io/job/merck-co-spclst-process-engineering-mst-upstream-or-downstream","title":"Spclst, Process Engineering (MS&T) - Upstream or Downstream","company":{"id":3768,"name":"Merck & Co.","domain":"msd.com","url":"https://alion.io/company/msd","size_band":"5000+","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"A","score":100,"open_postings":123,"ghost_share":0.008,"stale_share":0.122,"repost_share":0.089,"time_to_fill_p50_days":15,"computed_at":"2026-10-24T06:02:35Z"}},"role":"Industrial Engineering","role_family":"Industrial Engineering","seniority":null,"employment_type":"full_time","work_mode":"hybrid","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Dublin, Ireland"],"countries":["IE"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":59000,"max_usd":127000,"period":"year","method":"role_country_seniority_unknown","sample_n":103},"experience_years_min":null,"visa_sponsorship":true,"relocation_package":false,"has_equity":false,"technologies":[{"name":"CAPA","optional":false},{"name":"Cell Culture","optional":false},{"name":"FMEA","optional":false},{"name":"GMP","optional":false},{"name":"Statistical Process Control","optional":false},{"name":"Mandiant capa","optional":true}],"status":"closed","first_seen_at":"2026-09-28T13:26:58Z","employer_posted_date":"2026-09-28","last_verified_at":"2026-10-23T16:23:50Z","board_verified":false,"closed_at":"2026-10-23T16:23:50Z","days_open":25,"trust":{"level":"not_scored","repost_count":null,"flags":[],"days_open":25},"description":"Job Description\nOur Biotech facility in Dublin began construction in 2018 and has progressed at an impressive rate since then. The site plays a pivotal role in the manufacture of our Company’s biologics-based medicines, including immuno-oncology, and it has expanded our Company’s current internal network of biologics drug substance manufacturing plants since full manufacturing operations began in 2021.\nWe have a great opportunity for a Specialist MS&T to join the team; we welcome candidates with either upstream or downstream process engineering experience. The successful candidate will be placed within the upstream or downstream team based on their relevant experience, technical expertise, and organizational requirements.\nThe Specialist MS&T (process engineering & NPI) supports sustaining activities, manages and drives process qualification and validation related activities. Supports the design, construction and qualification of upstream & downstream equipment, NPI/technology transfer and commercialization at our Biotech site.\nEnsures that MS&T team objectives are effectively achieved, consistent with our company and requirements to ensure compliance, safety and reliable supply to our customers.\nBring energy, knowledge, innovation to carry out the following:\nEnsure compliance with Global Policies, Procedures and Guidelines, regulatory requirements and execute current Good manufacturing Practices (cGMP) in the performance of day-to-day activities and all applicable job functions.\nSupport the execution of development and PPQ batches, change control management and implementation.\nAssist in and facilitate investigations, ensuring effective Root Cause Analysis and CAPAs.\nParticipate in audits and inspections.\nSupport continuous improvement through Lean Six Sigma methodologies.\nSupport various site initiatives to improve compliance status and overall operational efficiency of the site.\nSupport the experimental design, execution, data analysis and interpretation.\nInterpret trends observed in commercial process monitoring (e.g., proactive process analysis (PPA), continued process verification (CPV), statistical process control (SPC) multivariate analyses (MVDA)), and for further technical investigations and process changes that seek to drive improvements to yield and/or robustness.\nAuthor and review of batch documentation, technical reports and global regulatory submissions.\nSupport multidisciplinary teams (manufacturing science and technology, quality, analytics, regulatory) for process improvement and troubleshooting with end-to-end product focus.\nApply Lean Six Sigma tools by\nSecuring continuity of an appropriate LSS/CEM level of knowledge.\n\nFacilitating problem solving & risk assessment (FMEA) projects/meetings.\n\nMaking problems visible and strive for continuous improvement.\n\nServe as a key member during internal audits and external inspections/audits.\nLead and support various MS&T organizational initiatives as needed (examples include safety, financial forecasting, work standardization, etc).\nMaintain continuous focus on quality and safety compliance and unflinching focus on the customer.\nIn order to excel in this role, you will more than likely have:\nDegree in (Bio) Chemistry, Process Technology, Biotechnology, Engineering or\ncomparable.\nExperience with upstream cell culture and/or downstream purification of biological\nmolecules.\nExperience with technology transfer, regulatory filing and commercial drug substance manufacturing of biologics is preferred but not essential\nExperience in change management, deviations and CAPAs management (desirable)\nWe keep the patient at the very heart of all that we do and strive to find solutions and treatments for some of the world's most challenging healthcare needs.\nWe are committed to flexible working where possible, and this is why our Company has introduced a new hybrid working model for office-based colleagues around the world.\nPlease feel free to speak to us about what flexibility means to you during your application.\nSo, if you are ready to:\nInvent solutions to meet unmet healthcare needs, please apply today.\nRequired Skills:\nCAPA Investigations, Cell Cultures, Manufacturing Operations, Process Control, Six Sigma, Technology TransferPreferred Skills:\nCurrent Employees apply HERE\nCurrent Contingent Workers apply HERE\nSearch Firm Representatives Please Read Carefully\nMerck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.\nEmployee Status:\nRegularRelocation:\nVISA Sponsorship:\nTravel Requirements:\nFlexible Work Arrangements:\nHybridShift:\nValid Driving License:\nHazardous Material(s):\nJob Posting End Date:\n10/13/2026*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.","description_format":"text","description_chars":5399,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"master","optional":false},"security_clearance":false,"languages":[]},"benefits":["Flexible schedule","Hybrid work"],"hiring_locations":[{"name":"Ireland","iso":"IE","kind":"country"}],"hiring_excludes":[],"relocation_offered":true,"industries":["Chemical Engineering","Financial Services","Biologics & Biosimilars","Bioprocessing"],"lifecycle":[{"event":"open","at":"2026-09-28T13:26:58Z"},{"event":"close","at":"2026-10-23T16:23:50Z"}],"visa":[],"liveness":null,"pay":null,"html_url":"https://alion.io/job/merck-co-spclst-process-engineering-mst-upstream-or-downstream","json_url":"https://alion.io/job/merck-co-spclst-process-engineering-mst-upstream-or-downstream.json","meta":{"generated_at":"2026-10-24T21:24:03Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":31419,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-25T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":3768},"rest":"https://alion.io/mcp/rest/get_company?id=3768"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fmerck-co-spclst-process-engineering-mst-upstream-or-downstream"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fmerck-co-spclst-process-engineering-mst-upstream-or-downstream"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fmerck-co-spclst-process-engineering-mst-upstream-or-downstream"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/merck-co-spclst-process-engineering-mst-upstream-or-downstream\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fmerck-co-spclst-process-engineering-mst-upstream-or-downstream"}]}