{"id":108156,"url":"https://alion.io/job/moderna-inc-principal-systems-engineer-digital-lab-systems","title":"Principal Systems Engineer, Digital Lab Systems","company":{"id":5847,"name":"Moderna","domain":"modernatx.com","url":"https://alion.io/company/modernatx","size_band":"1001-5000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"A","score":89,"open_postings":11,"ghost_share":0,"stale_share":0.455,"repost_share":0,"time_to_fill_p50_days":56,"computed_at":"2026-10-31T05:58:55Z"}},"role":"Hardware","role_family":"Hardware","seniority":"lead","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Norwood, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":145900,"max":234200,"currency":"USD","period":"year","gross":null,"usd_annual":234200},"salary_estimate":null,"experience_years_min":8,"visa_sponsorship":false,"relocation_package":false,"has_equity":true,"technologies":[{"name":"Agile","optional":false},{"name":"C++","optional":false},{"name":"CAPA","optional":false},{"name":"GCP","optional":false},{"name":"Git","optional":false},{"name":"GLP","optional":false},{"name":"Java","optional":false},{"name":"LIMS","optional":false},{"name":"Machine Learning","optional":false},{"name":"Python","optional":false},{"name":"Rest API","optional":false},{"name":"SOAP","optional":false}],"status":"live","first_seen_at":"2026-08-19T00:00:00Z","employer_posted_date":"2026-08-19","last_verified_at":"2026-10-31T15:16:18Z","board_verified":true,"closed_at":null,"days_open":73,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":73},"description":"The Role\nModerna is seeking a Principal Systems Engineer, Digital Lab Systems who will serve a key role supporting the delivery and administration of laboratory systems. The individual will assist in configuration and deployment of systems, participate in generating and maintaining necessary procedure. Activities will also include authoring and executing test protocols.\nHere's What You'll Do:\nServe as a technical leader for laboratory automation within the QC Laboratory, supporting and expanding automation capabilities across testing and sample management operations.\n\nDesign, develop, implement, and optimize automated workflows for QC assays utilizing advanced liquid handling platforms, including Hamilton technologies and Hamilton VENUS software.\n\nLead the deployment of integrated automation solutions, including dynamic scheduling platforms that enable efficient coordination of laboratory processes.\n\nTranslate manual laboratory workflows into scalable, high-throughput, automated systems that improve efficiency, consistency, and operational performance.\n\nAct as the subject matter expert for complex automation troubleshooting, root cause analysis, and technical issue resolution across automation platforms.\n\nDevelop and implement solutions that enable seamless data integration between laboratory instruments, automation systems, LIMS platforms, and enterprise applications.\n\nDesign, build, and maintain robust data structures, data pipelines, and workflow architectures supporting laboratory automation.\n\nDevelop and support system integrations using REST APIs, web services, middleware technologies, and modern connected laboratory architectures.\n\nContribute to the development and implementation of AI-enabled and machine learning-driven laboratory workflows, automation enhancements, and decision-support capabilities.\n\nProvide technical leadership and operational support for automated workcell platforms, including systems such as Hamilton CTUs.\n\nEnsure operational readiness, reliability, maintenance, and performance optimization of automated sample storage and biobanking systems.\n\nSupport commissioning, qualification, validation, and lifecycle management activities for automation and sample management platforms.\n\nDrive improvements in sample tracking, inventory control, storage efficiency, and end-to-end sample management processes.\n\nServe as system owner for critical laboratory automation platforms, ensuring reliability, compliance, and continuous improvement.\n\nEvaluate, identify, and implement new automation technologies, software solutions, and digital capabilities that support future laboratory needs.\n\nLead investigations into automation deviations, system issues, and performance gaps, implementing corrective and preventive actions where required.\n\nMaintain accurate documentation, technical records, and system configurations in accordance with SOPs, regulatory requirements, and quality standards.\n\nEnsure automation systems operate in compliance with applicable GLP and GCLP requirements and support validated laboratory operations.\n\nInterface with vendors and technology partners to support system implementation, optimization, upgrades, and long-term platform strategy.\n\nMentor junior engineers and provide technical guidance to colleagues across automation initiatives.\n\nDeliver training and knowledge transfer to laboratory personnel on automation platforms, workflows, and best practices.\n\nThe key Moderna Mindsets you’ll need to succeed in the role:\nWe digitize everywhere possible using the power of code to maximize our impact on patients.\nWe obsess over learning. We don’t have to be the smartest, we must learn the fastest.\nHere’s What You’ll Need (Basic Qualifications)\nBachelor’s or master’s degree in engineering, Computer Science, Biotechnology, Robotics, or related field\n\n8+ years of experience in laboratory automation or robotics\n\nExperience with liquid handling systems and automation platforms\n\nExperience integrating systems using APIs (REST or similar), databases, or middleware technologies\n\nProgramming experience in Python, Java, C++, or similar\n\nExperience with data structures, database design, and LIMS integration\n\nExposure to AI/ML applications in laboratory or automation workflows\n\nExperience with Hamilton platforms (VENUS, BiOS)\n\nFamiliarity with web services (REST/SOAP) and distributed systems\n\nExperience in regulated environments (GCP, GLP, ISO standards)\n\nKnowledge of version control (Git) and Agile methodologies\n\nStrong troubleshooting and communication skills\n\nPay & Benefits\nAt Moderna, we believe that when you feel your best, you can do your best work.That’s why our benefits and well-being resources are designed to support you-at work, at home, and everywhere in between.\nCompetitive healthcare, plus voluntary benefit programs to support your unique needs\nA holistic approach to well-being, with access to fitness, mindfulness, and mental health support\nFamily planning benefits, including fertility, adoption, and surrogacy support\nGenerous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown\nSavings and investments to help you plan for the future\nLocation-specific perks and extras\nThe salary range for this role is $145,900.00 - $234,200.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs.\n\nThe successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.\nAbout Moderna\nSince our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.\nBy living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.\nWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.\nIf you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.\nOur Working Model\nAs we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.\nModerna is a smoke-free, alcohol-free, and drug-free work environment.\nEqual Opportunities\nModerna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!\nModerna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.\nAccommodations\nWe’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.\nModerna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at .\n#LI-AG2-","description_format":"text","description_chars":8786,"description_truncated":false,"requirements":{"experience_years_min":8,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":["Equity"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Prescription Drugs","Vaccines","Infectious Disease Therapeutics"],"lifecycle":[{"event":"open","at":"2026-08-19T00:00:00Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 101 · green card filings: 27","filings_12m":101,"filings_prev_12m":150,"green_card_filings_12m":27,"median_offered_wage_usd":146797,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":33,"band":"fade","label":"Fading","p_open":1,"p_active":0.741,"p_room":0.44,"age_days":73,"expected_fill_days":56,"reasons":["conf:4","velocity","win:tail","crowd:brand"],"computed_at":"2026-10-31T05:58:55Z"},"pay":{"stated_usd_annual":234200,"is_top_pay":true},"html_url":"https://alion.io/job/moderna-inc-principal-systems-engineer-digital-lab-systems","json_url":"https://alion.io/job/moderna-inc-principal-systems-engineer-digital-lab-systems.json","meta":{"generated_at":"2026-10-31T17:59:29Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":28161,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-01T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":5847},"rest":"https://alion.io/mcp/rest/get_company?id=5847"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fmoderna-inc-principal-systems-engineer-digital-lab-systems"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fmoderna-inc-principal-systems-engineer-digital-lab-systems"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fmoderna-inc-principal-systems-engineer-digital-lab-systems"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/moderna-inc-principal-systems-engineer-digital-lab-systems\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fmoderna-inc-principal-systems-engineer-digital-lab-systems"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":108156}},{"tool":"search_jobs","arguments":{"company":"modernatx.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":108156},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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