{"id":3970597,"url":"https://alion.io/job/mumilk-analytical-development-lead","title":"Analytical Development Lead","company":{"id":679744,"name":"Mumilk","domain":"numi.life","url":"https://alion.io/company/numi","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workable","truth_index":null},"role":"Biotech","role_family":"Biotech","seniority":"lead","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Paris, France"],"countries":["FR"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":null,"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Cell Culture","optional":false},{"name":"ELISA","optional":false},{"name":"GLP","optional":false},{"name":"HPLC","optional":false},{"name":"ICH Guidelines","optional":false},{"name":"Mass Spectrometry","optional":false},{"name":"Western Blot","optional":false}],"status":"live","first_seen_at":"2026-11-09T15:55:16Z","employer_posted_date":"2026-11-09","last_verified_at":"2026-11-09T15:55:16Z","board_verified":true,"closed_at":null,"days_open":0,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":0},"description":"About Nūmi\nNūmi is a bioproduction platform harnessing human mammary cells to produce key ingredients with proven health benefits across all stages of life. More specifically, it is the first European cultivated breast milk company aiming to produce human milk constituents to better match the ideal nutrition for babies but also improve healthy aging. We are an early-stage, VC-backed biotech based in the heart of Paris (Hôpital Cochin, Paris 14th) and supported by world-class investors and scientific partners.\nNūmi's Values\nPositivity: At Nūmi, we cultivate positivity every day. Our mission drives us to communicate with passion and energy, always keeping the bigger impact in sight. We celebrate quick wins, but never lose track of our ultimate goal.\nExcellence: At Nūmi, excellence starts with dedication and a commitment to constant improvement. We embrace challenges as opportunities to learn and push ourselves to deliver high-quality results. Through effort, attention to detail, and integrity, we grow both individually and collectively as a team.\nTeam-Work and Pedagogy: At Nūmi, we believe that teamwork makes us stronger. We encourage knowledge-sharing, open feedback, and mutual respect. Each Nūmiz is here to lift others up, ensuring that the collective succeeds.\nAmbition: At Nūmi, we set ambitious goals and challenge ourselves to think big. Nūmi is driven by bold ideas and relentless determination, always aiming for the stars to create real impact.\n\nWhy this role matters\nAs Nūmi scales its ingredient portfolio (bioactive proteins such as lactoferrin, human milk oligosaccharides, functional lipids) from bench to pilot and first regulatory batches, we are looking for an Analytical Development Lead to characterise our ingredients in depth and build the analytical methods that measure them. You will define what we measure, how we measure it and how reliable each result is, for every ingredient we produce.\nReporting to our CTO Eugénie, you will work hand in hand with our Process Development team (upstream and downstream), our Reg & QC Implementation Lead and our Preclinical & Bioactivity Lead. Your data will drive process decisions and feed our regulatory dossiers.\nThis is a role for an analytical scientist with solid hands-on experience characterising complex ingredients (proteins, oligosaccharides or lipids) and developing methods for them, who now wants to build the analytical platform of a first-of-its-kind product category.\nKey Responsibilities\nIngredient Characterisation\nDefine and deliver Nūmi's analytical strategy across the ingredient portfolio, from R&D samples to pilot and regulatory batches.\nBuild the full characterisation package of each ingredient: identity and structure, purity, composition, isoforms and post-translational modifications for proteins, oligosaccharide and lipid profiles.\nBenchmark our ingredients against their human milk counterparts and marketed references in terms of structure and sequences.\nCharacterise the process-related impurities specific to a cell culture process: host cell proteins, residual DNA, media components.\nMethod Development and Validation\nDevelop, optimise and qualify fit-for-purpose analytical methods for each ingredient (LC-MS, HPLC/UPLC, HPAEC-PAD, electrophoresis, immunoassays), and validate them following ICH Q2 principles.\nDecide what to build in-house and what to run with external labs, and transfer methods to QC or partner labs.\nSet up reference standards, system suitability criteria and method documentation (SOPs, validation reports).\nProcess Support, Specifications and Stability\nProvide fast, reliable in-process and release analytics to the upstream and downstream teams, so every process decision rests on solid data.\nPropose release specifications and certificates of analysis for each ingredient.\nDesign and run stability studies, and batch-to-batch and scale comparability studies.\nCross-Functional Collaboration\nProvide the analytical data, method descriptions and test material characterisation that our Reg & QC Implementation Lead and external partners need for regulatory dossiers and safety studies.\nManage external analytical labs: scoping, follow-up and critical review of results.\nPartner with our Data team so every analytical result lands in a structured, queryable dataset.\nInnovation and Digital Tools\nEvaluate and integrate new analytical technologies and AI-enabled tools that speed up data analysis and reporting.\nRequirements\nExperience & Knowledge\nPhD in analytical chemistry, biochemistry, food science or a related discipline with 7+ years of industry experience, or MSc with 10+ years, in analytical development or product characterisation for food ingredients, infant nutrition or biologics.\nSolid hands-on track record characterising complex ingredients (proteins, oligosaccharides or lipids): identity, purity, composition, impurities.\nProven experience developing and validating analytical methods, with hands-on command of LC-MS and LC-MS/MS, HPLC/UPLC (RP, SEC, IEX), HPAEC-PAD, SDS-PAGE, Western blot and ELISA.\nThe documentation rigour of a quality-controlled lab (for example GLP, or an ISO 17025 accredited lab).\nExperience working with external analytical labs or CROs.\nProject & Process Leadership\nAbility to run several analytical projects in parallel and to set priorities with process and regulatory teams.\nAbility to turn complex analytical data into clear reports for scientific and regulatory audiences.\nComfortable working across departments in a fast-paced startup environment.\nCommunication\nExcellent written and spoken English. French is a plus.\nBonus\nIdeally, you have experience in some, but not necessarily all, of the following areas:\nHMOs, lactoferrin or other milk proteins, infant formula ingredients.\nProducts from mammalian cell culture (host cell proteins, residual DNA).\nProteomics, glycomics or lipidomics; NMR for structural elucidation.\nSpecification setting and stability studies for food ingredients.\nExposure to regulatory dossiers (Novel Food, GRAS) or safety studies.\nQbD and DoE approaches.\nStartup or scale-up environment (Series A to C).\nBenefits\n Unique opportunity to be one of the first senior hires at an early-stage biotech company, shaping the future of infant nutrition.\n Growth opportunities: you will have the opportunity to grow with the company and shape Nūmi's analytical function as it scales.\n Access to top-quality facilities, research services and infrastructure.\n Competitive salary, ESOP, part health insurance coverage, part transportation and lunch coverage.\n⭐ Employee-first mentality, we prioritize the well-being of our team members, both in terms of their mental and physical health.\nRecruitment process\nInitial skills matching.\nFirst interview with our cofounder and CTO Eugénie.\nA technical case study: design the characterisation and method development plan for one of our ingredients.\nA last interview on-site to meet our cofounder and CEO Eden, part of the team and visit the labs.\n2 to 3 reference calls.\nNūmi is committed to building a diverse and inclusive workplace. 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