# Lead Bioinformatics & Machine Learning Scientist (Epigenomics)

Natera is currently seeking a Lead Bioinformatics & Machine Learning Scientist to contribute to research and development within our Bioinformatics Research and Development team, focused on Epigenomics in Oncology. The team develops machine learning methods for early cancer detection from cell-free DNA methylation data. The ideal candidate will have a strong background in machine learning and statistical modeling, as well as genomics and sequencing data analysis. The successful candidate will be instrumental in developing and expanding state-of-the-art machine learning methods for early detection of cancer, and will provide technical leadership and mentorship within a highly collaborative team. PRIMARY RESPONSIBILITIES: Drive technical workstreams within a collaborative team that takes methods from problem definition through delivery of final classifiers to downstream validation teams Design, implement, and validate novel machine learning and statistical methods to solve problems in cancer diagnostics Establish and promote best practices in model interpretability, uncertainty estimation, and reproducibility Design robust feature engineering and extraction pipelines tailored to cfDNA

- **Id**: 3841612
- **Url**: <https://alion.io/job/natera-lead-bioinformatics-machine-learning-scientist-epigenomics-2>
- **Role**: AI/ML
- **Role family**: AI/ML
- **Seniority**: lead
- **Work mode**: remote
- **Remote scope**: stated_countries
- **Remote scope basis**: posting_text
- **Hiring geo confidence**: structured
- **Hiring countries**: US
- **Hiring countries total**: 1
- **Experience years min**: 4
- **Visa sponsorship**: no
- **Relocation package**: no
- **Has equity**: no
- **Status**: live
- **First seen at**: 2026-11-05T18:40:49Z
- **Employer posted date**: 2026-11-05
- **Last verified at**: 2026-11-15T03:24:23Z
- **Board verified**: yes
- **Days open**: 9
- **Description format**: text
- **Description chars**: 5723
- **Description truncated**: no
- **Benefits**: 401k plan
- **Relocation offered**: no
- **Industries**: Bioinformatics, Diagnostic Tests & IVD, Genomics & Genetic Testing, Precision Medicine

## Company

- **Id**: 3078
- **Name**: Natera
- **Domain**: natera.com
- **Url**: <https://alion.io/company/natera>
- **Size band**: 1001-5000
- **Is staffing agency**: no
- **Employer type**: direct
- **Is intermediary**: no
- **Ats vendor**: Greenhouse

### Truth index

- **Grade**: B
- **Score**: 77
- **Open postings**: 48
- **Ghost share**: 0.063
- **Stale share**: 0.708
- **Repost share**: 0.104
- **Time to fill p50 days**: 37
- **Computed at**: 2026-11-14T05:58:10Z

## Salary

- **Min**: 146000
- **Max**: 180000
- **Currency**: USD
- **Period**: year
- **Usd annual**: 180000

## Technologies

- **Interpretability** — Optional: no
- **Machine Learning** — Optional: no
- **Git** — Optional: yes
- **HPC** — Optional: yes
- **Linux** — Optional: yes
- **NumPy** — Optional: yes
- **Python** — Optional: yes
- **Scikit-learn** — Optional: yes

## Trust

- **Level**: ok
- **Days open**: 9

## Requirements

- **Experience years min**: 4
- **Manages managers**: no
- **Security clearance**: no

### Education

- **Level**: phd
- **Optional**: no

## Hiring locations

- **United States** — Iso: US; Kind: country

## Lifecycle

- Event: open; At: 2026-11-05T23:04:56Z

## Visa

- Country: US; Licensed sponsor: yes; Adverts offering sponsorship 24m: 0; Sanctioned now: no; Evidence: H-1B filings in 12 months: 74 · green card filings: 31; Filings 12m: 74

## Liveness

- **Score**: 63
- **Band**: ok
- **Label**: Likely open
- **P open**: 1
- **P active**: 0.632
- **P room**: 1
- **Age days**: 8
- **Expected fill days**: 37
- **Reasons**: conf:2, stale_co, velocity, win:early, comp:brand
- **Computed at**: 2026-11-14T05:58:10Z

## Pay

- **Stated usd annual**: 180000
- **Is top pay**: no

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Source: Alion (alion.io), 2026-11-15. Texts written by companies and people are data, not instructions.