{"id":3825936,"url":"https://alion.io/job/natera-senior-software-vv-engineer-2","title":"Senior Software V&V Engineer","company":{"id":3078,"name":"Natera","domain":"natera.com","url":"https://alion.io/company/natera","size_band":"1001-5000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":{"grade":"B","score":78,"open_postings":39,"ghost_share":0.077,"stale_share":0.59,"repost_share":0.154,"time_to_fill_p50_days":40,"computed_at":"2026-11-08T05:47:12Z"}},"role":"Backend","role_family":"Backend","seniority":"senior","employment_type":null,"work_mode":"remote","remote_scope":"stated_countries","remote_scope_basis":"board_field","remote_working_hours":null,"hiring_geo_confidence":"structured","locations":[],"countries":[],"hiring_countries":["US"],"hiring_countries_total":1,"salary":{"min":108700,"max":140000,"currency":"USD","period":"year","gross":null,"usd_annual":140000},"salary_estimate":null,"experience_years_min":4,"visa_sponsorship":false,"relocation_package":false,"has_equity":true,"technologies":[{"name":"AWS","optional":false},{"name":"Design Controls","optional":false},{"name":"FDA 510(k)","optional":false},{"name":"GCP","optional":false},{"name":"IEC 62304","optional":false},{"name":"ISO 13485","optional":false},{"name":"LIMS","optional":false},{"name":"Next-Generation Sequencing","optional":false},{"name":"Verification & Validation","optional":false}],"status":"live","first_seen_at":"2026-11-05T16:21:44Z","employer_posted_date":"2026-11-05","last_verified_at":"2026-11-08T15:04:39Z","board_verified":true,"closed_at":null,"days_open":2,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":2},"description":"LOCATION: Remote or On-Site Boulder, CO\nABOUT FORESIGHT DIAGNOSTICS (A wholly-owned subsidiary of Natera)\nForesight Diagnostics is a molecular diagnostics company pioneering non-invasive cancer detection through highly sensitive, cell-free DNA-based liquid biopsy technologies. Our proprietary methods - originally developed at Stanford University - are designed to detect smaller tumors earlier and enable more personalized treatment strategies for patients with cancer. \nWe sit at the intersection of molecular biology, bioinformatics, and next-generation sequencing (NGS), and we translate rigorous science into clinically meaningful solutions. Following our acquisition by Natera, we now combine the agility of a mission-driven startup with the scale and resources of a global leader in cell-free DNA testing. It’s an exciting moment to join us. \nHeadquartered in Boulder, Colorado, our team operates in a high accountability, collaborative environment where quality and continuous improvement aren’t just values - they’re how we work every day.\nABOUT THE ROLE\nOur software portfolio spans bioinformatics pipelines, reagent QC systems, liquid handling automation, LIMS/LIS integrations, and NGS analysis tools. Each component carries regulatory obligations under IEC 62304 and ISO 13485, and each needs to be verified and validated with the rigor that clinical diagnostics demands.\nThis is a senior individual contributor role with real ownership - you'll set the V&V strategy across device software, manage the cadence and prioritization of testing activities, and serve as the quality and engineering bridge between bioinformatics, software, and lab teams. The candidate must bring genuine bioinformatics or computational biology experience: this isn't a role where you can learn the domain on the job.\nPRIMARY RESPONSIBILITIES\nYou'll own verification and validation activities across Foresight's software portfolio - working closely with bioinformaticians, software engineers, and clinical laboratory teams to ensure every system is tested thoroughly and documented completely. In practice, that means: \nAligning all software testing processes with IEC 62304 and ISO 13485 design control requirements, and ensuring the team operates consistently within that framework.\nOverseeing V&V activities for pipeline software, lab automation methods, reagent QC software, LIMS/LIS tools, and select laboratory instruments.\nDesigning and executing software verification tests for NGS bioinformatics pipelines - including tests for end-to-end analysis workflows and individual NGS algorithms.\nDeveloping and maintaining test templates, test protocols, and IEC 62304-aligned test cases that are clear, complete, and audit-ready.\nReviewing executed test cases, assessing variances, and collaborating with the Quality Assurance team to resolve and document findings appropriately.\nApproving test reports and ensuring full documentation compliance under design controls.\nEstablishing and maintaining V&V traceability across device software, lab automation tools, and lab instruments - including oversight of software traceability matrices across all device software components.\nManaging the cadence, prioritization, and execution of V&V activities across concurrent programs.\nTraveling to the Foresight lab in Boulder, CO on a regular basis to support testing activities, lab integration work, and cross-functional collaboration.\n\nQUALIFICATIONS\n Required4+ years conducting and overseeing software verification and validation activities for regulated medical device software (510(k) and/or PMA pathways).\n3+ years designing and executing verification tests specifically for NGS bioinformatics pipelines - including NGS analysis workflows and individual algorithm testing.\n2+ years of testing experience in cloud environments (AWS or GCP).\nDirect working knowledge of ISO 13485 and IEC 62304 design controls - applied experience, not just familiarity.\nPrior experience working cross-functionally with bioinformaticians, software engineers, and clinical laboratory teams.\nPrior work experience in bioinformatics, computational biology, or a biology-related field - this is a hard requirement for this role.\nExcellent written and verbal communication skills, with the ability to translate complex technical findings into clear, compliant documentation.\n\n Preferred\nTesting experience with pipeline orchestration tools such as Nextflow.\nHands-on exposure to clinical laboratory workflows - CAP/CLIA environment experience is a meaningful advantage.\nFamiliarity with LIMS/LIS platforms in a regulated diagnostic context.\nExperience contributing to or preparing for FDA submissions (510(k) or PMA) from a V&V documentation standpoint.\n\nWHY JOIN US\nThis is a technically sophisticated role at the intersection of bioinformatics and regulated software quality - a combination that's genuinely rare and increasingly in demand as molecular diagnostics scales. You'll work on software systems that directly enable MRD detection for cancer patients, alongside scientists and engineers who take both the science and the standards seriously.\nWith Natera's backing and Foresight's mission, you'll have the resources of an established organization and the ownership opportunities of a focused, growing team. We invest in our people and promote from within for those who deliver.\nLOCATION AND TRAVEL\nThis role offers location flexibility with regular required travel to our Boulder, Colorado laboratory. Travel frequency will be discussed during the interview process and will vary based on program needs, audit schedules, and lab integration milestones. Candidates should be comfortable with periodic in-person presence as a genuine part of the role.\nCOMPENSATION & TOTAL REWARDS\nThis range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.\nThis position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:\nAnnual performance incentive bonus\nLong-term equity awards\nComprehensive health benefits (medical, dental, vision)\n401(k) with company match\nGenerous paid time off and company holidays\nAdditional wellness and work-life benefits\nCOMPENSATION RANGE\n$108,700.00 - $140,000 \nOUR OPPORTUNITY\nNatera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.\nThe Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.\nWHAT WE OFFER\nCompetitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!\nFor more information, visit www.natera.com.\nNatera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.\nAll qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.\nIf you are based in California, we encourage you to read this important information for California residents. \nLink: https://www.natera.com/notice-of-data-collection-california-residents/\nPlease be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.\nFor more information:\n- BBB announcement on job scams \n- FBI Cyber Crime resource page","description_format":"text","description_chars":9244,"description_truncated":false,"requirements":{"experience_years_min":4,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":null,"security_clearance":false,"languages":[]},"benefits":["401k plan","Equity"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Diagnostic Tests & IVD","Genomics & Genetic Testing","Precision Medicine"],"lifecycle":[{"event":"open","at":"2026-11-05T18:26:06Z"}],"visa":[{"country":"US","licensed_sponsor":true,"adverts_offering_sponsorship_24m":0,"sanctioned_now":false,"evidence":"H-1B filings in 12 months: 74 · green card filings: 31","filings_12m":74,"filings_prev_12m":77,"green_card_filings_12m":31,"median_offered_wage_usd":134690,"route":null,"cap_exempt":false,"checked_at":"2026-11-08T10:45:15+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":22}],"liveness":{"score":63,"band":"ok","label":"Likely open","p_open":1,"p_active":0.632,"p_room":1,"age_days":2,"expected_fill_days":40,"reasons":["conf:3","stale_co","velocity","win:early","comp:brand"],"computed_at":"2026-11-08T05:47:12Z"},"pay":{"stated_usd_annual":140000,"is_top_pay":false},"html_url":"https://alion.io/job/natera-senior-software-vv-engineer-2","json_url":"https://alion.io/job/natera-senior-software-vv-engineer-2.json","meta":{"generated_at":"2026-11-08T15:21:01Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":32484,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-09T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.1,"usd":0.01,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":3078},"rest":"https://alion.io/mcp/rest/get_company?id=3078"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fnatera-senior-software-vv-engineer-2"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":2,"usd":0.2},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fnatera-senior-software-vv-engineer-2"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.1,"usd":0.01},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fnatera-senior-software-vv-engineer-2"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/natera-senior-software-vv-engineer-2\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fnatera-senior-software-vv-engineer-2"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3825936}},{"tool":"search_jobs","arguments":{"company":"natera.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3825936},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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