{"id":1131138,"url":"https://alion.io/job/olema-oncology-vice-president-of-information-technology","title":"Vice President of Information Technology","company":{"id":678678,"name":"Olema Oncology","domain":"olema.com","url":"https://alion.io/company/olema","size_band":"201-500","is_staffing_agency":false,"is_intermediary":false,"ats_vendor":"Greenhouse","truth_index":{"grade":"B","score":75,"open_postings":3,"ghost_share":0,"stale_share":1,"repost_share":0,"time_to_fill_p50_days":null,"computed_at":"2026-09-23T05:45:00Z"}},"role":"Leadership","role_family":"Leadership","seniority":"head","employment_type":null,"work_mode":"on_site","remote_scope":null,"hiring_geo_confidence":"explicit","locations":["San Francisco, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":194000,"max_usd":362000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":1323},"experience_years_min":15,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Agile","optional":false},{"name":"GDPR","optional":false},{"name":"HIPAA","optional":false},{"name":"Service Desk","optional":false}],"status":"live","first_seen_at":"2026-09-22T23:15:41Z","employer_posted_date":"2026-09-23","last_verified_at":"2026-09-23T08:06:29Z","board_verified":true,"closed_at":null,"days_open":0,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":0},"description":"Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It’s an exciting time to be part of Team Olema, with our transformation into a fully integrated oncology company well underway, top-line data from our lead program expected later this year, and our first potential commercial launch on the horizon.\nOur lead product candidate, palazestrant, is a novel, orally available complete estrogen receptor antagonist (CERAN) and selective estrogen receptor degrader (SERD) currently in two pivotal Phase 3 clinical trials. We expect top-line data from OPERA-01, our ongoing Phase 3 trial of palazestrant as a monotherapy in patients with second- or third-line ER+/HER2- metastatic breast cancer (MBC), in the fall which, if successful, could lead to our first potential approval and commercial launch in 2027. OPERA-02, our Phase 3 trial of palazestrant in combination with ribociblib in patients with frontline ER+/HER2- MBC, is enrolling patients. Together with its mechanism of action, pharmacokinetic properties, and the potential to demonstrate activity in both ESR1 wild-type and mutant tumors, palazestrant has the potential to transform the metastatic breast cancer treatment paradigm and access a $15 billion global market opportunity.\nOur follow-on product candidate, OP-3136, is a potent KAT6 inhibitor with the potential to generate further value and meaningfully impact the metastatic breast cancer treatment landscape - particularly in combination with palazestrant. We recently reported encouraging Phase 1 monotherapy data from this program across multiple solid tumor types and are advancing patient enrollment in the ongoing combination arms in MBC.\nAspiring to transform the metastatic treatment paradigm is an ambitious endeavor that requires a resolute approach to developing better therapies and a passionate team dedicated to helping the patients we serve feel better, longer. We possess a deep commitment to our shared purpose, the sustained pursuit of excellence, cultivating the courage required to advance our programs, drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution. Team Olema is made up of nimble self-starters who bring consistency in their quest for the extraordinary every single day.\nIf you’re ready to be part of a tenacious, courageous, agile, and growing team, join us in making a profound impact, together - for our patients, for your career, and for what’s beyond.\nAbout the Role >>> Vice President of Information Technology \nThe Vice President of Information Technology will serve as Olema’s senior technology leader and will own the strategy, security, and day-to-day operations and delivery of the global IT function. This leader will identify, build, and refine the new and existing systems, technology, tools, cybersecurity, and artificial intelligence capabilities the business requires as we advance our programs and toward our first potential product approval and commercial launch in the US. \nThe role will partner closely with leaders across the business, including Commercial, Medical Affairs, Regulatory Affairs, Quality, Clinical Development, Pharmacovigilance, Manufacturing and Supply Chain, and G&A. The ideal candidate will combine hands-on IT experience and leadership, deep Microsoft and O365 expertise, and demonstrable commercial launch experience with a strong enterprise-wide mindset and sound judgment in a fast-paced, highly regulated environment. This individual must also be an AI-forward leader and strong advocate for the rapid, responsible implementation of AI tools and frameworks to improve decision-making, productivity, service delivery, and organizational scalability. \nThis position is based in Olema’s San Francisco office and will require regular travel to Boston and Ireland, as needed. \nYour work will primarily encompass: \nEnterprise IT Strategy \nDefine and execute a multi-year enterprise IT strategy and applications roadmap aligned with business goals across research, development, commercial, and corporate functions. \nSet efficientandscalable architecture, integration, cloud, SaaS, data, and technology lifecycle standards that support growth without unnecessary complexity. \nEstablish a strategic and effective IT operating model, including internal capabilities, outsourced services, governance, and decision rights. \nEstablish disciplined intake, prioritization, funding, and delivery processes that make value, cost, risk, capacity, and dependencies visible. \nAdvise the Executive Committee on technology investments, performance, cybersecurity, and risk. \nOwn IT budgets, vendors, and major implementation partners. \n IT Operations \nAccountable for the reliable operation of Olema's technology environment, including cloud services, networks, identity and access management, endpoints, collaboration platforms, telecommunications, conference-room technology, service desk, and end-user computing. \nEnsure technology readiness for new offices, Ireland operations, commercial field teams, and workforce growth, including capacity planning, provisioning, connectivity, access, equipment, training, local support, and business continuity. \nOwn major IT incidents from detection through restoration, executive communication, root-cause analysis, and verified remediation. Ensure business-critical processes have tested recovery, manual workarounds, and accountable continuity plans. \nEstablish a senior client relationship model across every function, including regular roadmap reviews, service and project scorecards, demand planning, decision logs, and clear escalation paths. Ensure leaders understand priorities, constraints, ownership, and delivery commitments. \nPartner with Finance to ensure systems and integrations support accurate, timelyclose and reporting, budgetingand forecasting, purchasingcontrols, vendor and expense management, SOX IT general controls, audit evidence, and scalable public-company operations. \nMaintain disciplined technology assetand software license management across the full lifecycle, including procurement, deployment, inventory, maintenance, renewal, and secure disposition. \nDevelop effectiveIT reporting standards (e.g., dashboards, scorecards, etc.) to communicate network performance, incident trends, resolution times, employee satisfaction, adoption, security, controls, project health, vendor performance, budget, technical debt, and launch readiness. \nSet targets for major IT investments, measure benefits following implementation, and use results to guide priorities and funding.Ownthe outcomes after implementation. Confirm configuration quality, integrationcompleteness, data quality, control effectiveness, adoption, performance, support readiness, and realized value before a system is considered fully delivered. \nLead IT-relatedvendor selection, contract negotiation, governance, performance management, and renewal decisions in partnership with Legal, Finance, Procurement, and business owners. \nBuild and lead a high-performing team of individual contributors, managers, contractors, and managed service providersappropriate forOlema’s stage and growth trajectory. \nRegulatory Approval and Commercial Launch Readiness \nDevelop and ownthe integratedIT commercial readiness plan basedon anticipatedregulatoryapprovaland launch timelines.Partner with Commercial and G&A leadership to define and execute the technology and data roadmap for launch. \nSupport Commercialin identifyingtheplatforms and servicesrequiredfor a successful launch, including customer relationship management, field systems, commercial data and analytics, master data, digital engagement, market access, and patient support capabilities. \nPartner with Manufacturing and Supply Chain to support product planning, inventory, distribution, third-party logistics, serialization and traceability, order management, and revenue reporting. \nSupport launch-critical Medical Affairs and Pharmacovigilance IT capabilities, including medical information, field medical operations, adverse event reporting, product complaints, and related safety obligations. \nEnsure launch-critical IT systems have clear business ownership, requirements, validation or assurance strategies, integrations, support models, training plans, and contingencies. \nLead cross-functional IT readiness from requirements and vendor selection through integration, testing, training, cutover, stabilization, and post-launch support. \nIdentifycritical-path technology risks early and manage dependencies, governance, readiness metrics, mitigation plans, and executive escalation. \nCybersecurity,Compliance,and Risk \nDevelop and own the company’scybersecurity strategy and control environment that protects systems, data, intellectual property, clinical and patient information, employee information, and regulated records. \nPartner with Quality to maintaincompliance with GxP, 21 CFR Part 11, SOX, privacy, computer system validation or assurance, data integrity, records retention, and applicable global requirements. \nPartner with HR, Legal, Privacy, Quality, and Compliance to address applicable privacy and security obligations, including HIPAA, GDPR, state privacy laws, and relevant international requirements. \nOversee business continuity, disaster recovery, backup, incident response, identity and access management, endpoint security, vulnerability management, security monitoring, and third-partyrisk. \nMaintain inspection and audit readiness, ensure critical vendors are appropriately assessed and monitored, and provide clear security, compliance, and risk metrics to executive leadership and the Board. \nApply a risk-basedComputer Software Assurance approach to GxPsystems and maintainsufficient knowledge of FDA CSA guidance to oversee validation strategy and challenge implementation decisions. \nArtificial Intelligence and Digital Innovation \nDefine theenterprise data and artificial intelligence strategyacross scientific, clinical, commercial, and corporate priorities, with a practical roadmap tied to measurable business outcomes. \nEstablishan AI governance process in partnership with Compliance, Legal, and Quality,including risk-based review, data protection, human oversight, and controls for regulated use cases. \nBuild a secure data and platform foundation for artificial intelligence and measure adoption, time saved, cycle time, quality, cost, value, and risk. \nEvaluate emerging technology with technical curiosity and disciplined experimentation. Scale solutions only when security, reliability, integration, support, adoption, and economic value have been demonstrated. \nIdeal Candidate Profile >>> \nRequired \nStrong understanding of biotechnology and pharmaceutical processes from development through commercialization. \nDeep knowledge of commercial technology and data capabilities requiredfor a United States pharmaceutical launch. \nAbility to design and manage a clearcompany-wide architecture, with rigorous technical reviews, observable services, explicit service-level objectives, thoughtful automation, strong security, and excellent user experience. \nExpertiseand provenknowledge of the Microsoft/O365environmentand other enterprise applications, architecture, cloud and SaaS platforms, data, cybersecurity, service management, and responsible artificial intelligence. \nKnowledge of GxP, 21 CFR Part 11, SOX, privacy, validation, data integrity, and vendor risk management. \nBachelor’sdegree is required. An advanced degree in business, information technology, science, or a related discipline is strongly preferred. \nExperience \nMinimum of 15years of progressive information technology experience, including senior leadership responsibility in a biotechnology or pharmaceuticalcompany. \nDemonstrated success in building, leading, and developing high-performing IT teams, including individual contributors, manag...","description_format":"text","description_chars":17550,"description_truncated":true,"requirements":{"experience_years_min":15,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":["Equity"],"hiring_locations":[{"name":"Ireland","iso":"IE","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Health Care","Pharmaceuticals","Information Security","Biopharma"],"lifecycle":[{"event":"open","at":"2026-09-23T03:08:39Z"}],"liveness":{"score":86,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.86,"p_room":1,"age_days":0,"expected_fill_days":43,"reasons":["conf:2","win:early"],"computed_at":"2026-09-23T05:45:00Z"},"pay":null,"html_url":"https://alion.io/job/olema-oncology-vice-president-of-information-technology","json_url":"https://alion.io/job/olema-oncology-vice-president-of-information-technology.json","meta":{"generated_at":"2026-09-23T10:53:52Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers"}}