{"id":3765740,"url":"https://alion.io/job/parexel-principal-clinical-database-programmer-ecoa","title":"Principal Clinical Database Programmer - eCOA","company":{"id":2735,"name":"Parexel","domain":"parexel.com","url":"https://alion.io/company/parexel","size_band":"5000+","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"B","score":84,"open_postings":46,"ghost_share":0,"stale_share":0.826,"repost_share":0.022,"time_to_fill_p50_days":19,"computed_at":"2026-11-08T05:47:12Z"}},"role":"Backend","role_family":"Backend","seniority":"lead","employment_type":"full_time","work_mode":"remote","remote_scope":"stated_countries","remote_scope_basis":"board_field","remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Sheffield, United Kingdom","Harrow, United Kingdom"],"countries":["GB"],"hiring_countries":["GB"],"hiring_countries_total":1,"salary":null,"salary_estimate":null,"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"21 CFR Part 11","optional":false},{"name":"Good Clinical Practice","optional":false},{"name":"Matter","optional":false},{"name":"Medidata Rave","optional":false}],"status":"live","first_seen_at":"2026-11-03T00:00:00Z","employer_posted_date":"2026-11-03","last_verified_at":"2026-11-09T00:04:25Z","board_verified":true,"closed_at":null,"days_open":6,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":6},"description":"When our values align, there's no limit to what we can achieve.\nAt Parexel, we all share the same goal - to improve the world's health. From clinical trials to regulatory, consulting, and market access, every clinical development solution we provide is underpinned by something special - a deep conviction in what we do.\nEach of us, no matter what we do at Parexel, contributes to the development of a therapy that ultimately will benefit a patient. We take our work personally, we do it with empathy and we're committed to making a difference.\nJoin Parexel as a Principal Database Programmer - eCOA (eCOA Study Builder/Designer), a fully home-based opportunity open to candidates across the UK!\nPicture Yourself at Parexel:\nWe are seeking a Principal Database Programmer (eCOA Study Builder /Designer) specializing in electronic Clinical Outcome Assessment (eCOA) solutions. As a Principal Database Programmer (eCOA Study Builder/ Designer), you will provide technical expertise for the design, configuration, testing, deployment, and maintenance of eCOA solutions used in clinical trials. This position plays a key role in study execution, regulatory compliance, and clinical data accuracy. You will translate protocols, assessment schedules, and licensed instrument requirements into compliant participant, caregiver, and clinician facing questionnaires, schedules, and workflows. You will collaborate with sponsors and cross-functional teams, follow industry-standard processes, and contribute to eCOA study delivery from design through closeout. Responsibilities include configuring and testing eCOA studies in approved platforms and supporting their integration with Electronic Data Capture (EDC) systems, with opportunities to deepen your expertise and influence study outcomes.\nWhat You'll Do At Parexel:\nDesign, Set Up, Maintain, Revise and Close Out eCOA Studies:\nInterpret protocols, schedules of assessments, eCOA specifications and licensed instrument requirements to design appropriate electronic data collection workflows.\nConfigure questionnaires, screens, field properties, code lists, schedules, activities, completion settings, branching logic, rules, reminders, alerts, notifications and study settings in the approved eCOA platform.\nApply established naming conventions and build standards, including clear identification of eCOA-specific forms, fields and code lists.\nCoordinate the initial eCOA configuration and controlled push to EDC; maintain alignment among the eCOA configuration, EDC draft and applicable CRF versions.\nAssess and implement approved protocol amendments, production revisions, translations and study maintenance changes while protecting data integrity and traceability.\nTesting, Validation and Deployment:\nPerform technical quality control of eCOA configurations against approved specifications, including screens, questionnaire workflows, rules, notifications and schedules.\nPrepare system demonstrations, test evidence, questionnaire screenshots and other materials required for internal review and User Acceptance Testing (UAT).\nSupport pre-UAT meetings, UAT execution, defect triage and resolution; ensure issues are documented in the approved study issue-tracking process.\nCoordinate deployment readiness and communicate completion of technical quality control and UAT prerequisites to applicable stakeholders.\nSupport post-production troubleshooting and controlled implementation of approved corrections. \nProject and Stakeholder Support:\nCollaborate with Clinical Database Programming, Data Management, eCOA Clinical Data Analysis, COA Science, Clinical Operations, and other study functions to finalize eCOA requirements and resolve design issues.\nLead or participate in recurring design and build meetings, provide configuration status, identify risks and dependencies, and escalate issues when required.\nInteract with sponsors and vendors as a technical contact for eCOA design, specification, testing and deployment topics, as assigned.\nProvide input to study timelines, monitor assigned work and communicate changes in scope, assumptions or resourcing needs.\nProvide technical advice to internal project teams and support multiple projects simultaneously.\nDocumentation and Compliance:\nCreate and maintain eCOA specifications, configuration records, implementation checklists, test evidence, screenshots, issue records, version documentation, and other required study artifacts.\nMaintain study documentation in accordance with SOPs, Work Instructions, and guidelines to support traceability, inspection readiness, and regulatory compliance.\nDocument deviations, decisions, risks, and configuration limitations and communicate them to the appropriate project stakeholders.\nFollow system life cycle, access control, change control, validation and records-management requirements. \nSupport Technologies, Standards and Continuous Improvement:\nProvide technical solutions to internal and external client inquiries relating to eCOA study design and its interaction with EDC and other clinical systems.\nParticipate in the development and maintenance of standards, reusable libraries, templates, checklists, tools and processes that improve eCOA delivery quality and efficiency.\nIdentify recurring defects or process gaps, contribute to root-cause analysis and support implementation of corrective or preventive improvements.\nAct as a Trainer and/or Subject Matter Expert:\nProvide role-relevant training, coaching, and technical guidance to project teams and less-experienced study designers, as appropriate.\nAssist project teams in resolving complex configuration, workflow, and integration issues.\nSupport Business Development:\nProvide technical input to proposals, assumptions, effort estimates, client presentations, and bid-defense meetings, as requested.\nRequired Experience, Knowledge, and Skills:\nBachelor's degree in life sciences, computer science, health informatics, clinical research or a related discipline.\nWritten and oral fluency in English.\nProven experience with eCOA, ePRO, eDiary is required.\nStrong clinical research industry experience (CRO/Pharma) is required.\nHands-on experience configuring an eCOA platform such as Medidata Designer eCOA, or comparable study-design technology, is preferred.\nKnowledge of questionnaire design, schedules, branching logic, reminders, notifications, translations, version management, and participant workflows.\nExperience with EDC systems, preferably Medidata Rave, and understanding of eCOA-to-EDC configuration dependencies and data flow.\nKnowledge of SOPs, Work Instructions, system life-cycle methodologies, ICH-GCP, 21 CFR Part 11 and other applicable local and international regulatory requirements.\nExperience with technical quality control, UAT, defect management, change control and validated clinical systems.\nExperience supporting global studies, sponsors, and cross-functional project teams.\nStrong ability to collaborate with global, cross-functional teams and work independently across multiple time zones and cultures.\nExcellent communication skills, including the ability to explain technical design decisions to technical and non-technical audiences.\nAbility to interpret clinical protocols, schedules of assessments, questionnaires and technical specifications and translate them into system configurations.\nProven problem-solving skills, including root-cause analysis, risk identification and decision-making in ambiguous situations.\nCustomer focus and the ability to interact professionally with sponsors, vendors and internal colleagues.\nProficient presentation and system-demonstration skills.","description_format":"text","description_chars":7621,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[{"language":"English","level":"Advanced (C1)","optional":false}]},"benefits":[],"hiring_locations":[{"name":"United Kingdom","iso":"GB","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Clinical Trial Software","Clinical Trial Services (CRO)"],"lifecycle":[{"event":"open","at":"2026-11-04T20:01:52Z"}],"visa":[{"country":"GB","licensed_sponsor":true,"adverts_offering_sponsorship_24m":0,"sanctioned_now":false,"evidence":"Licensed UK visa sponsor (Senior or Specialist Worker, Skilled 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