{"id":2810418,"url":"https://alion.io/job/pascall-systems-senior-algorithm-engineer","title":"Senior Algorithm Engineer","company":{"id":4390100,"name":"Pascall Systems","domain":"pascallsystems.com","url":"https://alion.io/company/pascallsystems","size_band":null,"is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Ashby","truth_index":null},"role":"Industrial Engineering","role_family":"Industrial Engineering","seniority":"senior","employment_type":"full_time","work_mode":"hybrid","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Cambridge, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":130000,"max":150000,"currency":"USD","period":"year","gross":null,"usd_annual":150000},"salary_estimate":null,"experience_years_min":5,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"AI Agents","optional":false},{"name":"AWS","optional":false},{"name":"ChatGPT","optional":false},{"name":"Claude","optional":false},{"name":"Claude Code","optional":false},{"name":"Copilot","optional":false},{"name":"Cursor","optional":false},{"name":"LLM","optional":false},{"name":"Machine Learning","optional":false},{"name":"Python","optional":false},{"name":"Time Series","optional":false}],"status":"live","first_seen_at":"2026-09-21T21:07:31Z","employer_posted_date":"2026-09-21","last_verified_at":"2026-10-22T10:27:19Z","board_verified":true,"closed_at":null,"days_open":30,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":30},"description":"Position Summary\nPASCALL is a growing multidisciplinary medical device company building an FDA-cleared, EEG-based brain state monitoring platform - a wearable EEG sensor paired with an Android tablet application - now in active clinical use. As our platform matures and enters more hospitals, we are hiring a Senior Algorithm Engineer to lead the development of the signal processing and machine learning models at the core of the product.\nWe are looking for a self-motivated engineer and scientist who treats an open problem as an invitation - someone who invents, prototypes, and champions ideas that create measurable business value. This is a hands-on, technically deep role based in Cambridge, working closely with our CEO, our product team, and our device/hardware team. You'll own algorithm development end-to-end: from feature extraction and artifact removal through to real-time state estimation, validated and documented to the standard required for a regulated medical device.\nPASCALL actively uses agentic AI tools to accelerate development, documentation, and algorithm research. We welcome engineers who are comfortable experimenting with AI-assisted workflows and applying them responsibly in a regulated environment.\nIn addition, because the team is small and much of the algorithm roadmap is still being written, you will have unusual latitude to shape what gets built. We invite you to bring creative approaches to problems that have no established answer and to argue for the bets you believe in.\nResponsibilities\nDesign and Own Signal Processing Algorithms: Develop and refine algorithms for feature extraction, artifact removal and parameter estimation from EEG signals, spanning statistical time-series methods, control-engineering approaches and state-space modeling.\n\nBuild Real-Time, Deployable Estimators: Design sequential, real-time algorithms - including Kalman filtering and related recursive estimation techniques - that run reliably on the device in live clinical settings.\n\nAdvance the Brain State Platform: Drive the next generation of brain-state estimation and related algorithm deliverables, working across the full path from research prototype to shipped, validated feature.\n\nLead Regulated Algorithm Development: Define, write, and validate algorithms under PASCALL's Quality Management System, producing the documentation, verification, and validation evidence needed for FDA submissions in partnership with Quality and Regulatory.\n\nUse AI-assisted tools (e.g., LLM-powered coding assistants, automated documentation) to accelerate development tasks.\n\nApply AI tools responsibly within PASCALL's regulated development environment.\n\nMentor and Set Technical Direction: Provide technical leadership to the algorithm team, review designs and code and help set the standards other engineers build against.\n\nCollaborate Across Disciplines: Partner closely with the device/hardware, software, and clinical teams to ensure algorithms perform correctly in real-time and reflect real clinical needs.\n\nSolve Hard Problems: Investigate and root-cause complex, intermittent issues across the signal path - from sensor to algorithm output - bringing inventive, unconventional approaches when the obvious path is blocked.\n\nInnovate on the Product: Prototype new ideas quickly, propose approaches nobody has asked for, and think past the current architecture about what the platform's algorithms could do for clinicians, hospitals and the business.\n\nQualifications\nEducation\nAdvanced degree (PhD) in Statistics, Mathematics, Computational Neuroscience, Biomedical or Electrical Engineering, Computer Science, Computational Biology or a related field.\n\nExperience and Skills\n5+ years of industry experience developing signal processing or machine learning algorithms for production-level systems. Medical device or other regulated industry experience strongly preferred.\n\nStrong command of statistical signal processing, including time-series and frequency-domain/spectral analysis.\n\nStrong command of biomedical signal processing, including control engineering, state-space modeling,\n\nsequential algorithms and Kalman filtering.\n\nStrong coder in Python with solid scientific engineering practices (you write reusable modules and libraries and use OOP where it makes sense).\n\nComfort using AI-assisted tools (e.g., GitHub Copilot, Claude / Claude Code, ChatGPT, Cursor) for coding and research.\n\nVersatility and initiative: ****you can take an ambiguous, high-level objective, scope it yourself, and run it to completion and you look for the next problem rather than waiting to be assigned one.\n\nCreativity and independent drive: ****a track record of thinking outside the box - finding a simpler algorithmic approach, repurposing a technique in an unexpected way, or solving something others had accepted as fixed and the self-motivation to pursue it without being asked.\n\nCommercial instinct: ****you understand how algorithm choices translate into customer adoption, regulatory timelines and revenue and can prioritize accordingly.\n\nClear communications: you are comfortable working across an interdisciplinary team of engineers, neuroscientists, and physicians.\n\nDocumentation rigor: ****you have the discipline to document algorithms, decisions and validation evidence precisely.\n\nPreferred\nSoftware engineering experience and knowledge of best practices.\n\nDirect experience developing a medical device or working under an FDA QSR- or ISO 13485-certified Quality Management System.\n\nExperience with AWS managed services, cloud computing and MLOps.\n\nComfort using AI-assisted development tools (e.g., Claude Code, GitHub Copilot, Cursor) responsibly in a regulated environment.\n\nEvidence of building something of your own - ****a side project, an internal tool that spread, a patent, a publication, or a product idea you took from sketch to something real.\n\nAbout PASCALL Systems\nPASCALL is a Cambridge-based medical device company focused on advancing neuroscience-based personalized anesthesia monitoring. Our team includes leading academic and clinical experts from MIT, Harvard, Stanford, and Massachusetts General Hospital.\nWe achieved ISO 13485 certification for medical device design and development and received FDA 510(k) clearance for our first platform system in 2022. We are now building the next generation of EEG-based brain state algorithms to improve anesthesia care and patient outcomes worldwide. We are a small team solving problems that do not have textbook answers, and we give engineers real ownership over the direction of the product.\nOur vision is to bring personalized, science-based anesthesia care to all patients.\nHow to Apply\nIn your Cover Letter, answer each of the following questions clearly:\n1. What excites you about this role and PASCALL's mission?\n2. Tell us about a technical project you are most proud of - ideally one involving signal processing, state\nestimation, or algorithm development under real-world constraints.\n3. Tell us about something you invented, prototyped, or improved that nobody asked you to build - what made you pursue it, and what value did it create?\nBenefits:\nDental insurance\n\nHealth insurance\n\nPaid parental leave\n\nPaid time off\n\nWork Location: Hybrid remote in Cambridge, MA 02139","description_format":"text","description_chars":7274,"description_truncated":false,"requirements":{"experience_years_min":5,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":["Dental insurance","Health insurance","Parental leave"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Health Care","Science & Engineering","Hospitals & Health Systems"],"lifecycle":[{"event":"open","at":"2026-10-18T09:22:12Z"}],"visa":[],"liveness":{"score":40,"band":"fade","label":"Fading","p_open":1,"p_active":0.721,"p_room":0.55,"age_days":30,"expected_fill_days":27,"reasons":["conf:2","win:tail"],"computed_at":"2026-10-22T06:10:10Z"},"pay":{"stated_usd_annual":150000,"is_top_pay":true},"html_url":"https://alion.io/job/pascall-systems-senior-algorithm-engineer","json_url":"https://alion.io/job/pascall-systems-senior-algorithm-engineer.json","meta":{"generated_at":"2026-10-22T13:05:50Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":11980,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-23T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":4390100},"rest":"https://alion.io/mcp/rest/get_company?id=4390100"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fpascall-systems-senior-algorithm-engineer"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fpascall-systems-senior-algorithm-engineer"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fpascall-systems-senior-algorithm-engineer"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/pascall-systems-senior-algorithm-engineer\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fpascall-systems-senior-algorithm-engineer"}]}