{"id":3685042,"url":"https://alion.io/job/pfizer-senior-scientist-chemical-engineer-for-api-manufacturing-process-development","title":"Senior Scientist - Chemical Engineer for API Manufacturing Process Development","company":{"id":3480,"name":"Pfizer","domain":"pfizer.com","url":"https://alion.io/company/pfizer","size_band":"1001-5000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"A","score":88,"open_postings":28,"ghost_share":0,"stale_share":0.679,"repost_share":0,"time_to_fill_p50_days":13,"computed_at":"2026-11-10T06:52:35Z"}},"role":"Data Science","role_family":"Data Science","seniority":"senior","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Groton, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":93600,"max":156000,"currency":"USD","period":"year","gross":null,"usd_annual":156000},"salary_estimate":null,"experience_years_min":9,"visa_sponsorship":true,"relocation_package":true,"has_equity":false,"technologies":[{"name":"Knowledge Distillation","optional":false},{"name":"Model Distillation","optional":false},{"name":"HPLC","optional":true},{"name":"Machine Learning","optional":true},{"name":"MATLAB","optional":true},{"name":"Python","optional":true}],"status":"live","first_seen_at":"2026-11-02T00:00:00Z","employer_posted_date":"2026-11-02","last_verified_at":"2026-11-10T07:57:11Z","board_verified":true,"closed_at":null,"days_open":8,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":8},"description":"Use Your Power for Purpose\nAt Pfizer, our purpose is to deliver breakthroughs that change patients' lives. Central to this mission is our Research and Development team, which strives to translate advanced science and cutting-edge technologies into impactful therapies and vaccines. Whether you are involved in discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, your role is crucial. You will leverage innovative design and process development capabilities to accelerate the delivery of best-in-class medicines to patients globally.\nWhat You Will Achieve\nWe are seeking a highly motivated chemical engineer for the role of Senior Scientist-Chemical Engineer to join our API Process Development team within Chemical Research and Development (CRD) in Groton, CT. You will join a diverse team responsible for developing Active Pharmaceutical Ingredients (API) processes for use at manufacturing plants across Pfizer’s network. Chemical engineering principles contribute to the successful development, optimization and scale up of API manufacturing processes. You will design and perform engineering-related laboratory experiments, integrating process modeling, statistics, and automation. Strong communication, high technical aptitude, and creativity to foster original ideas are required for success in this position.\nCRD, as part of Pfizer R&D in Pharmaceutical Sciences, is responsible for the development of process technology to manufacture active pharmaceutical ingredients (API). CRD scientists engage in all facets of development from small-scale synthesis in support of medicinal chemistry programs, to the development and optimization of the commercial API manufacturing process. In collaboration with chemists and analysts, you will lead the engineering activities during process development, process scale up, and technology transfer to our clinical and commercial manufacturing sites and external facilities. Given the dynamic team environment and fast-paced project timelines, strong interpersonal and communication skills are essential. This laboratory-based position offers the opportunity for cross-training and developing new technologies.\nHow You Will Achieve It\nApply chemical engineering principles to design and perform laboratory experiments to develop and optimize API manufacturing unit operations.\nAssess scalability and robustness for API processes with understanding of large-scale pharmaceutical manufacturing equipment, capabilities, and operations.\nEvaluate, develop, and apply new process technologies (batch, semi-batch, and continuous flow) to deliver safe, efficient, and sustainable API processes.\nLead technology transfer of processes to internal clinical and commercial API manufacturing sites and external partners. May spend time at the commercial launch site supporting process validation activities. \nApply process simulation and statistical tools to characterize the kinetic, thermodynamic, and transport phenomena impacting various unit operations, such as reaction, extraction, distillation, crystallization, filtration, and drying.\nPrepare internal research reports and technical presentations summarizing API process development activities to capture process knowledge and transfer process understanding to Pfizer’s commercial manufacturing. \nChampion the development of new technology and digital tools to expedite new and existing workflows and capabilities.\nRemain current with the process engineering and chemistry literature. May collaborate on and author external publications and present research at external conferences.\nContribute to the preparation of the Chemistry and Manufacturing Controls (CMC) section of the New Drug Application (NDA). Participate in data verification, Pre-Approval Inspection (PAI) preparedness, and post-submission query response.\nHere Is What You Need (Minimum Requirements)\nBS with at least 9 years of experience or MS with at least 7 years of experience or PhD with 0+ years of experience in Chemical Engineering \nCandidates with additional years of work experience will be considered for an appropriate level for their background\nExpertise in reaction engineering, including experience developing and validating kinetic models from experimental data\nExcellent knowledge of chemistry and chemical engineering principles and sound understanding of chemical reactor design, thermodynamics, transport phenomena, engineering statistics, and process modeling\nOutstanding laboratory skills, attention to detail, and ability to solve technical problems\nExceptional interpersonal, multi-disciplinary team collaboration, and communication skills\nBonus Points If You Have (Preferred Requirements)\nWorking knowledge of reaction modeling, property prediction, and process simulation tools including: gPROMS, Aspen, DynoChem, VisiMix, and COSMOtherm\nExperience designing, developing, and scaling continuous processes (flow chemistry)\nA good foundational understanding of organic chemistry\nWorking knowledge of crystallization development\nWorking knowledge of Design of Experiment (DOE) studies and statistical analysis\nWorking knowledge of analytical techniques such as HPLC/UPLC, MS, PXRD, DSC, TGA, and NMR\nWorking knowledge of application of in-situ analysis tools to process understanding including: FTIR, Raman, FBRM, UV/Vis\nComputational fluid dynamics (CFD) expertise in M-Star or Fluent\nPrograming experience, including Python and/or Matlab\nApplied data science methods, such as machine learning and AI\nExperience in automating laboratory equipment and processes including use of LabView\nPHYSICAL/MENTAL REQUIREMENTS\nAbility to work in a laboratory environment performing experiments in a laboratory fume hood. Ability to perform complex data analysis\nNON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS\nSome international travel associated with technology transfer to clinical manufacturing plant and commercial new product launch site may be required.\nRelocation support available\nWork Location Assignment: On Premise\nLast day to apply : Nov 20th 2026\nThe annual base salary for this position ranges from $93,600.00 to $156,000.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.Relocation assistance may be available based on business needs and/or eligibility.\nCandidates must be authorized to be employed in the U.S. by any employer.\nU.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.\nSunshine Act\nPfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.\nEEO & Employment Eligibility\nPfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.\nPfizer endeavors to makewww.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.\nTo learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.\nResearch and Development","description_format":"text","description_chars":9734,"description_truncated":false,"requirements":{"experience_years_min":9,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":["Relocation assistance"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":true,"industries":["Prescription Drugs","Oncology Therapeutics","Infectious Disease Therapeutics"],"lifecycle":[{"event":"open","at":"2026-11-03T14:37:23Z"}],"visa":[{"country":"US","licensed_sponsor":true,"adverts_offering_sponsorship_24m":115,"sanctioned_now":false,"evidence":"H-1B filings in 12 months: 47 · green card filings: 2","filings_12m":47,"filings_prev_12m":91,"green_card_filings_12m":2,"median_offered_wage_usd":127296,"route":null,"cap_exempt":false,"checked_at":"2026-11-09T07:32:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)","Alion: sponsorship offered in the employer's own job adverts (24 months)"],"filings_for_role_12m":12}],"liveness":{"score":56,"band":"ok","label":"Likely open","p_open":1,"p_active":0.62,"p_room":0.9,"age_days":8,"expected_fill_days":13,"reasons":["conf:5","stale_co","velocity","win:mid","comp:brand"],"computed_at":"2026-11-10T06:52:35Z"},"pay":{"stated_usd_annual":156000,"is_top_pay":true},"html_url":"https://alion.io/job/pfizer-senior-scientist-chemical-engineer-for-api-manufacturing-process-development","json_url":"https://alion.io/job/pfizer-senior-scientist-chemical-engineer-for-api-manufacturing-process-development.json","meta":{"generated_at":"2026-11-10T08:36:44Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":19980,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-11T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.1,"usd":0.01,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":3480},"rest":"https://alion.io/mcp/rest/get_company?id=3480"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fpfizer-senior-scientist-chemical-engineer-for-api-manufacturing-process-development"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":2,"usd":0.2},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fpfizer-senior-scientist-chemical-engineer-for-api-manufacturing-process-development"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.1,"usd":0.01},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fpfizer-senior-scientist-chemical-engineer-for-api-manufacturing-process-development"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/pfizer-senior-scientist-chemical-engineer-for-api-manufacturing-process-development\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fpfizer-senior-scientist-chemical-engineer-for-api-manufacturing-process-development"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3685042}},{"tool":"search_jobs","arguments":{"company":"pfizer.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3685042},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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