{"id":3179680,"url":"https://alion.io/job/precision-medicine-group-principal-scientist-2","title":"Principal Scientist","company":{"id":449981,"name":"Precision Medicine Group","domain":"precisionmedicinegrp.com","url":"https://alion.io/company/precision-medicine-group-2","size_band":"1001-5000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":{"grade":"B","score":81,"open_postings":17,"ghost_share":0,"stale_share":0.765,"repost_share":0,"time_to_fill_p50_days":40,"computed_at":"2026-11-05T05:54:30Z"}},"role":"Science & Research","role_family":"Science & Research","seniority":"lead","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Houston, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":66000,"max_usd":181000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":541},"experience_years_min":10,"visa_sponsorship":true,"relocation_package":false,"has_equity":false,"technologies":[{"name":"GLP","optional":false},{"name":"qPCR","optional":false}],"status":"live","first_seen_at":"2026-10-23T17:21:01Z","employer_posted_date":"2026-10-23","last_verified_at":"2026-11-05T17:45:11Z","board_verified":true,"closed_at":null,"days_open":13,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":13},"description":"Position Summary:\nThe Principal Scientist will be instrumental in helping Precision achieve its goals of delivering exceptional services to Precision’s diverse, innovative, and global biopharmaceutical clients. Working closely with the assigned manager, the Principal Scientist will help support key scientific projects ensuring best practices are implemented to support timely delivery of client projects. Key components will be focused on the design and development of innovative qualified and validated molecular assays including, but not limited to, ddPCR, qPCR, Next Gen Sequencing, Nanostring, and FISH assays.\nThe successful candidate will assist and be a resource for scientist team members to design experimental plans and timelines, that match client specifications/requirements. The candidate should be able to communicate project plans and progress to the client, along with executing and reporting the work according to agreed timelines and under the appropriate regulations (GLP, CAP, CLIA etc.). A significant aspect of this role is the training and mentoring of junior scientists and team members in both laboratory techniques and in the analysis and presentation of data. This role will provide technical expertise to the laboratory and perform “hands on” experiments as needed for training and mentoring purposes.\nEssential functions of the job include but are not limited to:\nDesigns, implements, and troubleshoots molecular assays with the scientific team to meet client requirements\nOversees the scientists writing and implementing standard operating procedures (SOPs) to perform assays to meet client requirements and the level of regulatory compliance needed\nOversees the generation of technical reports and other communications required to present data to clients\nHelps support the generation of posters and papers for submission to conference organizers and peer reviewed journals when applicable and approved by senior management\nReviews and edit client proposals, contract/proposals as needed\nTrains and mentors scientific staff in the review and presentation of client data; supports client calls as the leading expert for the team\nTrains and mentors technical staff on how to perform laboratory procedures. Devises and performs training and competency assessments to ensure staff can perform tasks independently\nMaintains and supports safe lab practices and environment\nTracks and trends laboratory efficiency and quality\nPerforms duties with a high degree of independence, quality, and efficiency\nActs as internal expert on technical advances to anticipate and act as a thought leader to management on all matters related to their scope of work.\nInitiates and/or recommends appropriate courses of action and identifies matters requiring policy interpretation or revision\nEnsures scope of work and change orders are followed by technical team, and minimizes scope creep\nHelps support the scheduling of work with the team, to ensure financial targets are being met by the lab staff\nQualifications:\nMinimum Required:\nMust have a Ph.D. in life sciences or relevant field (e.g. Molecular Biology)\nAt least 8 years related full-time laboratory experience\nOther Required:\nStrong bench scientist skills around molecular assays. Hands on sequencing, ddPCR, and qPCR experience is required.\nExperience in validation/qualification of assays to CAP/CLIA/GLP or ISO guidelines\nStrong organizational skills\nStrong communication skills\nExperienced technical report generation\nThe ability to see and differentiate between colors on the full color spectrum\nAbility to lift and carry between 1-15 lbs.; Ability to lift up to 50 lbs. overhead with assistance; frequently required to sit, grasp, and use right/left finger dexterity; May be exposed to a cold freezer environment (Freezer temperatures range between -20ºC -196ºC)\nMust be able to read, write, speak fluently, and comprehend the English language\nPreferred:\n10-15+ years’ experience as a molecular laboratorian in a leadership role with direct reports\nExperience supervising or mentoring scientists or technical personnel\nIndustrial experience and/or management of outside collaborations is desirable\nA solid understanding of current GxP or CAP/CLIA/ISO standards\nPrevious work experience in GLP or GCLP or CLIA regulatory compliance\nPrecision is required by law in some states or cities to include a reasonable estimate of the compensation range for this role. This compensation range takes into account the wide range of factors that are considered in making compensation decisions including but not limited to: skill sets, experience and training, licensure and certifications, and other business and organizational needs. The disclosed range estimate has not been adjusted for the applicable geographic differential associated with the location at which the position may be filled. At Precision, it is not typical for an individual to be hired at or near the top of the range for their role and compensation decisions are dependent on the facts and circumstances of each case. This role is also eligible for a discretionary annual bonus, health insurance, retirement savings benefits, life insurance and disability benefits, parental leave, and paid time off for sick leave and vacation, among other benefits.\nReasonable estimate of the current range\n$110,700—$166,100 USD\nAny data provided as a part of this application will be stored in accordance with our Privacy Policy. For CA applicants, please also refer to our CA Privacy Notice.\nPrecision Medicine Group is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law.\nIf you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact Precision Medicine Group at .\nRecruitment Fraud Warning: Please be aware that fraudulent individuals and websites may impersonate Precision Medicine Group or its affiliates and attempt to obtain personal, financial, or banking information through fake job postings or employment offers. Precision Medicine Group will never request payment, banking details, or other sensitive financial information as part of the recruitment process. If you believe you have been targeted by a recruitment scam, we encourage you to report the incident to your local law enforcement authorities, consumer protection agency, or relevant cybercrime reporting organization in your country. Please also notify us at  so we can investigate and take appropriate action.\nCandidates must be legally authorized to work in the country of employment without employer sponsorship.","description_format":"text","description_chars":6966,"description_truncated":false,"requirements":{"experience_years_min":10,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[{"language":"English","level":"All levels","optional":false}]},"benefits":["Health insurance","Life insurance","Parental leave"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Health Care","Clinical Trial Services (CRO)","Precision Medicine"],"lifecycle":[{"event":"open","at":"2026-10-23T20:58:20Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 2 · green card filings: 2","filings_12m":2,"filings_prev_12m":3,"green_card_filings_12m":2,"median_offered_wage_usd":87500,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":60,"band":"ok","label":"Likely open","p_open":1,"p_active":0.602,"p_room":1,"age_days":12,"expected_fill_days":40,"reasons":["conf:3","stale_co","win:early","comp:brand"],"computed_at":"2026-11-05T05:54:30Z"},"pay":null,"html_url":"https://alion.io/job/precision-medicine-group-principal-scientist-2","json_url":"https://alion.io/job/precision-medicine-group-principal-scientist-2.json","meta":{"generated_at":"2026-11-05T19:05:43Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":25607,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-06T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":449981},"rest":"https://alion.io/mcp/rest/get_company?id=449981"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fprecision-medicine-group-principal-scientist-2"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fprecision-medicine-group-principal-scientist-2"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fprecision-medicine-group-principal-scientist-2"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/precision-medicine-group-principal-scientist-2\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fprecision-medicine-group-principal-scientist-2"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3179680}},{"tool":"search_jobs","arguments":{"company":"precisionmedicinegrp.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3179680},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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