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Salary
≈ $46k – $94k per year (Estimated)
Location
In office (Oxford)
Seniority
Senior · 5+ years exp
Visa
Licensed UK visa sponsor
Employment
Contractor

Confirmed on the employer's own hiring board on Oct 20, 2026. First seen by Alion on Oct 16, 2026.

Overview
Company
Impact
Profile match
Proclinical is a life sciences recruitment and consulting firm headquartered in London that provides executive search, permanent and contract staffing and workforce solutions exclusively to pharmaceutical, biotech, medical device and related companies. Founded in 2005, it runs offices across Europe, North America and Asia-Pacific, including Basel, and places candidates with clients in Switzerland, the UK, the US and Australia. Its current listings are client roles such as scientists, automation and instrumentation engineers, GCP quality managers, project coordinators, finance analysts and veterinary technicians.

Are you a highly accomplished Immunologist with a track record of leading scientific teams and driving biologics discovery programmes in autoimmune and inflammatory diseases?

Proclinical is recruiting for a Principal Scientist, this position will oversee breakthrough work in inflammation and immunology. You'll play a central role in shaping therapeutic approaches, developing next-generation biologic therapies, mentoring talented scientists, and advancing programs from target identification to preclinical development.

Working at the forefront of immunology research, you will lead and support multidisciplinary programmes spanning target identification, pharmacology, translational research and therapeutic antibody development. You will combine hands-on scientific expertise with leadership, helping to advance novel biologic therapies from early discovery through preclinical development.

Responsibilities:

  • Lead and mentor a team of laboratory-based scientists, supporting both scientific delivery and career development
  • Design, oversee and interpret complex in vitro and in vivo pharmacology studies
  • Drive the development of novel therapeutic strategies within autoimmune and inflammatory disease programmes
  • Design and optimise immune-based assays to support target validation and antibody discovery
  • Collaborate closely with experts across immunology, translational medicine, protein engineering, biomarkers and clinical development
  • Work with CRO partners to coordinate efficacy and pharmacology studies
  • Develop and implement endpoint and mechanism-of-action studies, including ex vivo immune profiling
  • Identify project risks, influence programme strategy and support key decision-making discussions
  • Contribute to scientific publications, patents, regulatory documentation and due diligence activities
  • Represent research programmes through conference presentations and external scientific collaborations

Key Skills and Requirements:

  • PhD in Immunology, Life Sciences or a related discipline
  • Minimum 5 years' experience within immunology, inflammation research or biologics drug discovery
  • Strong understanding of autoimmune disease biology and immune system mechanisms
  • Proven experience leading scientific projects and mentoring research teams
  • Expertise across in vitro pharmacology, assay development and immune profiling
  • Experience supporting biologics, antibody or therapeutic development programmes
  • Strong publication record with peer-reviewed scientific contributions
  • Excellent communication, stakeholder management and leadership skills
  • Biotechnology or pharmaceutical industry experience
  • In vivo pharmacology programme leadership
  • Translational research and target validation experience
  • Experience working with CROs and external research partners
  • Contribution to IND-enabling studies, patent applications or due diligence activities
  • Exposure to strategic portfolio or pipeline decision-making

If you are having difficulty in applying or if you have any questions, please contact Neil Walton at [email protected].

If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists please request a call back at the top of this page.

Proclinical is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Proclinical is acting as an Employment Agency in relation to this vacancy.

By submitting this application, you confirm that you've read and understood our privacy policy, which informs you how we process and safeguard your data - https://www.proclinical.com/privacy-policy.

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