{"id":2950017,"url":"https://alion.io/job/prolific-machines-research-associate-cell-line-development-automation","title":"Research Associate, Cell Line Development Automation","company":{"id":685503,"name":"Prolific Machines","domain":"prolific-machines.com","url":"https://alion.io/company/prolific-machines","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Lever","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":"junior","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Emeryville, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":85000,"max":115000,"currency":"USD","period":"year","gross":null,"usd_annual":115000},"salary_estimate":null,"experience_years_min":2,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Cell Culture","optional":false},{"name":"Design of Experiments","optional":false},{"name":"Google Workspace","optional":false},{"name":"Microsoft Office","optional":false},{"name":"Molecular Cloning","optional":false},{"name":"PCR","optional":false}],"status":"live","first_seen_at":"2026-10-20T18:19:12Z","employer_posted_date":"2026-10-20","last_verified_at":"2026-10-22T08:41:56Z","board_verified":true,"closed_at":null,"days_open":1,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":1},"description":"We are seeking a motivated Research Associate II or Senior Research Associate to join our Automation/Cell Line Development (CLD) team, with a focus on laboratory automation and high-throughput workflows. In this role, you will develop and optimize automated workflows to support cell line development, contribute to pipeline projects, and conduct experiments to improve the performance of our optogenetic Chinese Hamster Ovary (CHO) cell lines. You will work at the intersection of laboratory automation, cell culture, and molecular biology, helping improve the efficiency, scalability, and reproducibility of our CLD processes. This role is based on-site at our headquarters in Emeryville, CA.\nResponsibilities:\nConduct experiments independently, collect and analyze data in a timely manner, and maintain detailed documentation in electronic lab notebooks.\nConduct experiments at the Automation/CLD interface and establish efficient automation workflows (Tecan or Hamilton) for CLD processes during seed train, production, or screening (Ambr or Beacon) processes.\nCommunicate successfully with any team, demonstrating the ability to compile and present across different teams and forums within the company. \nQuickly analyze and provide critical data and figures to support presentations, patent applications, or publications.\nCollaborate closely with members of the CLD team as well as other teams within Prolific Machines. Contribute to lab maintenance and safety as a good lab citizen.\nDevelop and optimize analytical methods, ensuring adherence to safety and operational standards, following established protocols, and providing data for regulatory submissions.\nThis is a lab-based position, and onsite presence is required as dictated by Automation and Cell Line Development (CLD) responsibilities and experimental needs.\nAbout You:\nQualifications:\nEducation & Experience: A Bachelor's degree with 2-5+ years of relevant industry experience or a Master's degree with 1-4+ years of relevant experience is expected for an RA II position. Additional experience and increased independence expected at the Sr. RA level.\nDesigning and Executing Experiments: Developing and proposing experimental plans, conducting experiments, and troubleshooting analytical techniques and methodologies\nWork Style: The candidate is expected to precisely follow protocols, design and execute experiments independently, and manage multiple tasks in a fast-paced setting.\n Communication Skills: Strong written and verbal communication skills are essential for documenting findings and effective collaboration. Familiarity with Microsoft Office (Word, Excel, PowerPoint) or Google Workspace (Docs, Sheets, Slides) software and ability to perform independent data analysis and generating meaningful conclusions is required.\nTechnical Experience: \nExperience with cell line development workflows (pool generation, clonal isolation, stability testing).\nExperience with automation systems used during CLD processes (scripting experience on the Tecan or Hamilton would be an added plus).\nExposure to high-throughput screening platforms (e.g., Beacon, Ambr, Octet, Cedex, and other regularly used Automation systems). \nExperience with molecular cloning and molecular biology techniques (PCR, protein quantification).\nWorking knowledge of statistical analysis or design of experiments (DoE). Comfort working in a dynamic, fast-paced R&D environment.\n(Nice to have) Familiarity with optogenetic systems, inducible promoters, or light-responsive protein engineering.\nAbout You:\nA successful candidate for this role will:\nHave a flexible and independent working attitude.\nAdapt successfully to changing situations and environments.\nHave a strong eagerness to learn.\nHave well-developed communication, teamwork, and organizational skills.\nBe proactive and drive to optimize workflows.\nThis is an individual contributor role within the Research Associate track. The position is best suited for candidates who excel in hands-on execution, instrumentation, and technical operations in a laboratory setting. Growth opportunities within this role are focused on deepening technical expertise, expanding instrument proficiency, and taking on increasing operational responsibility within the Cell Line Development function.","description_format":"text","description_chars":4284,"description_truncated":false,"requirements":{"experience_years_min":2,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":["Growth opportunities"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Synthetic Biology","Drug Discovery"],"lifecycle":[{"event":"open","at":"2026-10-20T19:44:13Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 1","filings_12m":1,"filings_prev_12m":1,"green_card_filings_12m":0,"median_offered_wage_usd":112500,"route":null,"cap_exempt":false,"checked_at":"2026-10-15T11:24:14+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)"],"filings_for_role_12m":0}],"liveness":{"score":86,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.86,"p_room":1,"age_days":1,"expected_fill_days":28,"reasons":["conf:1","win:early","comp:junior"],"computed_at":"2026-10-22T06:10:10Z"},"pay":{"stated_usd_annual":115000,"is_top_pay":true},"html_url":"https://alion.io/job/prolific-machines-research-associate-cell-line-development-automation","json_url":"https://alion.io/job/prolific-machines-research-associate-cell-line-development-automation.json","meta":{"generated_at":"2026-10-22T10:58:04Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":8529,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-23T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":685503},"rest":"https://alion.io/mcp/rest/get_company?id=685503"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fprolific-machines-research-associate-cell-line-development-automation"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fprolific-machines-research-associate-cell-line-development-automation"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fprolific-machines-research-associate-cell-line-development-automation"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/prolific-machines-research-associate-cell-line-development-automation\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fprolific-machines-research-associate-cell-line-development-automation"}]}