{"id":497913,"url":"https://alion.io/job/radical-numerics-product-lead-biodefense","title":"Product Lead, Biodefense","company":{"id":52611,"name":"Radical Numerics","domain":"radicalnumerics.ai","url":"https://alion.io/company/radicalnumerics","size_band":"201-500","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Ashby","truth_index":{"grade":"A","score":95,"open_postings":16,"ghost_share":0,"stale_share":0,"repost_share":0,"time_to_fill_p50_days":204,"computed_at":"2026-11-02T06:13:15Z"}},"role":"Product","role_family":"Product","seniority":"lead","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"explicit","locations":["San Francisco, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":163000,"max_usd":316000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":1090},"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"CRISPR","optional":true}],"status":"live","first_seen_at":"2026-08-25T03:52:58Z","employer_posted_date":"2026-08-25","last_verified_at":"2026-11-02T20:52:53Z","board_verified":true,"closed_at":null,"days_open":69,"trust":{"level":"ok","repost_count":0,"flags":["company_stale"],"days_open":69},"description":"About Us\nRadical Numerics is an AI research lab building general biological intelligence. Our mission is to master the code of life, and our purpose is to reduce human suffering.\nOur team created Evo, and started the field of generative genomics. Our work was featured on the cover of Science, and presented by our CEO on the main stage of TED2025. Evo was used to create the first AI-generated CRISPR-Cas9, and the first AI whole genome from scratch. Evo 2, featured in Nature, is the largest fully open source AI project across any domain.\nRadical Numerics is bringing the rigor of distributed systems, model architecture, and numerics research to the challenges of biology. We’ve redesigned the foundation model training stack to turn the world’s raw scientific data (e.g. biological sequences, experiments, and physical processes), into intelligible, generative models that can expand and accelerate what humanity can understand, design, and cure.\nThe same generative breakthroughs that enable life-saving cures also lowers the barrier to creating engineered threats and AI-generated bioweapons. We believe these forces are inseparable. Radical Numerics was founded to develop both the power to design and the responsibility to defend.\nAbout the Role\nYou own product and commercial execution for biodefense, helping to improve global preparedness and response capabilities against high-consequence biological risks. You track community needs and investment trends in biodefense and biosecurity and help decide which problems our model, Omnii, is ready to solve, and turn technical evaluations into funded deployments.\nOur science team owns the core model. You decide what gets built around it: how results enter an existing pipeline, what evidence a buyer needs, and how the software must run in the customer’s environment. You will have substantial say in the samples, comparators, acceptance criteria, and validations we use.\nThis is a hands-on role that will involve building collaborations with government and nongovernmental partners, working closely with our Head of Biodefense who leads policy, strategy, and senior relationships. You will build or guide early prototypes and work alongside an applications engineer who takes them into production. You own the product, the opportunity, and the path to award.\nWhat You’ll Do\nIdentify biosecurity and biodefense problems and help decide what we pursue, helping to target Omnii’s capacity to enhance risk mitigation, detection, characterization, diagnostic and countermeasure efforts, attribution, and other actions.\n\nSet the technical bar Omnii must clear before a customer uses its results.\n\nFind and develop government opportunities. Determine who holds the requirement, where the funding sits, and our comparative advantages.\n\nHelp embed Radical in the broad biodefense and biosecurity ecosystem through collaborations with targeted nongovernmental and global actors.\n\nDesign evaluations. That will often mean blinded retrospective studies, comparison against the currently fielded pipeline, and performance on the kinds of samples the customer actually handles-such as wastewater, clinical, or environmental samples.\n\nChoose what awards to pursue. Weigh the benefits and constraints of OTAs, BAAs, small-business programs, subcontracts, and direct awards.\n\nTurn deployment constraints into product requirements. These may include on-premises or disconnected operation, pinned model versions, provenance, auditability, and the evidence required for authorization.\n\nBuild or guide the building of prototypes that let a customer see how Omnii would work in its existing process, then work with applications engineering to make the successful ones deployable.\n\nOwn the commercial process through award. You will set pricing and deal structure with the Head of Biodefense and lead negotiations alongside legal.\n\nWhat We’re Looking For\nYou strive to bring the best possible capabilities to addressing biological threats.\n\nYou have personally helped win or deliver a technical program for the US government. You have been through an award cycle and understand who owns a requirement, which funding can pay for it, and how a promising pilot gets stranded.\n\nYou have working fluency in pathogen genomics, biosurveillance, or other relevant fields. You understand next-generation and metagenomic sequencing and pathogen-agnostic detection, what a false positive costs an operator at 3am, and why an inferior incumbent tool may still be difficult to replace.\n\nYou can hold your own with government scientists, turn their technical obstacles into product decisions, and explain those decisions clearly to our researchers and engineers.\n\nYou can build an early prototype yourself, enough to test a workflow, interrogate model output, or make a proposed product concrete for a customer.\n\nYou remain effective when the obstacle is data authority, software authorization, procurement, or an incumbent contract rather than model performance.\n\nYou are willing and eligible to pursue a US security clearance if the work requires it.\n\nNice to Have\nExperience inside a national laboratory, defense or public-health agency, government contractor, or FFRDC.\n\nExperience deploying scientific software into disconnected, authorized, or classified environments.\n\nScientific training or substantial professional experience in microbiology, virology, bioinformatics, synbio, countering-weapons of mass destruction, countermeasure development, or public health.\n\nFirsthand knowledge of existing biodefense and biosecurity programs and where to enhance their current workflows.\n\nRadical Numerics is committed to equal employment opportunity and does not discriminate in any employment opportunities or practices based on an individual's race, color, creed, gender (including gender identity and gender expression), religion (all aspects of religious beliefs, observance or practice, including religious dress or grooming practices), marital status, registered domestic partner status, age, national origin or ancestry (including language use restrictions and possession of a driver’s license issued under California Vehicle Code section 12801.9), natural hair, physical or mental disability, political affiliation, medical condition (including cancer or a record or history of cancer, and genetic characteristics), sex (including pregnancy, childbirth, breastfeeding or related medical condition), genetic information, sexual orientation, military and veteran status or any other consideration made unlawful by federal, state, or local laws. It also prohibits unlawful discrimination based on the perception that anyone has any of those characteristics, or is associated with a person who has or is perceived as having any of those characteristics.\nRadical Numerics participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S.","description_format":"text","description_chars":6949,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":null,"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Foundation Models","AI Research Labs"],"lifecycle":[{"event":"open","at":"2026-09-07T07:53:08Z"}],"visa":[],"liveness":{"score":68,"band":"ok","label":"Likely open","p_open":1,"p_active":0.856,"p_room":0.8,"age_days":69,"expected_fill_days":204,"reasons":["conf:2","win:early","crowd:"],"computed_at":"2026-11-02T06:13:15Z"},"pay":null,"html_url":"https://alion.io/job/radical-numerics-product-lead-biodefense","json_url":"https://alion.io/job/radical-numerics-product-lead-biodefense.json","meta":{"generated_at":"2026-11-03T00:03:15Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":136,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-04T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":52611},"rest":"https://alion.io/mcp/rest/get_company?id=52611"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fradical-numerics-product-lead-biodefense"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fradical-numerics-product-lead-biodefense"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fradical-numerics-product-lead-biodefense"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/radical-numerics-product-lead-biodefense\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fradical-numerics-product-lead-biodefense"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":497913}},{"tool":"search_jobs","arguments":{"company":"radicalnumerics.ai","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":497913},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. Docs: https://alion.io/developers"}}