{"id":1310288,"url":"https://alion.io/job/replimune-senior-scientist-analytical-development","title":"Senior Scientist, Analytical Development","company":{"id":2285234,"name":"Replimune","domain":"replimune.com","url":"https://alion.io/company/replimune","size_band":"201-500","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Ashby","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":"senior","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Abingdon, United Kingdom"],"countries":["GB"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":94000,"max_usd":186000,"period":"year","method":"role_seniority_country_cell","sample_n":8},"experience_years_min":5,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"CAPA","optional":false},{"name":"Ignite","optional":false},{"name":"PyTorch","optional":true}],"status":"closed","first_seen_at":"2026-07-20T17:46:06Z","employer_posted_date":"2026-07-20","last_verified_at":"2026-09-29T14:27:20Z","board_verified":false,"closed_at":"2026-09-29T14:27:20Z","days_open":70,"trust":{"level":"not_scored","repost_count":null,"flags":[],"days_open":70},"description":"Overview\nReplimune’s mission is to revolutionize cancer treatment with therapies designed to activate a powerful and durable full-body anti-tumor response, boldly transforming cancer care becausepatient’s lives depend on it.\nAt Replimune, we live by our values:\nUnited: We Collaborate for a Common Goal.\nAudacious: We Are Bold.\nDedicated: We Give Our Full Commitment.\nCandid: We Are Honest With Each Other.\nPeople are at the center of everything we do, and when it comes to our employees, we make it personal. With a deep sense of purpose, a strong and evolving culture, a competitive and forward-looking total rewards program, everyone at Replimune has a unique opportunity to impact on the lives of patients, caregivers and themselves.\nJoin us, as we reshape the future.\nSummary of job description:\nSr. Scientist Analytical Development is responsible for developing, optimizing, qualifying, and validating analytical methods based on new and existing methodologies to qualitatively and quantitatively evaluate both drug substance and drug product, from preclinical through late phase clinical development. Analytical development supports drug substance/drug product release, process development, and characterization and/or stability testing of Replimune’s clinical material. In addition, coordination of analytical development and analysis work at CMOs/CROs will be a significant portion of the duties of the Sr. Scientist Analytical Development.\nThis position is based in our Milton Park location and typically has a 5-day on-site expectation.\n\nKey responsibilities:\nManage the development, qualification and validation of analytical test methods and technology transfer in accordance with ICH and other regulatory guidances.\n\nSupport release and stability testing performed in house and at contract research organization (CRO), and directing good manufacturing practices (GMP) investigations including deviation root cause analyses, corrective action preventative action (CAPA), and out of specification (OOS).\n\nDevelop strategies for evaluating and implementing new technologies within Analytical Development.\n\nSupport process development, setting of specifications, and chemistry manufacturing and control (CMC) regulatory filings and responses.\n\nInvolved in daily workings of the group and actively participate in method troubleshooting and data analysis.\n\nOther responsibilities:\nSupervise the work of Assay Development Scientists or Technicians\n\nAnalytical Development (AD) representative for cross function meetings/projects with manufacturing, Quality Assurance (QA), Regulatory Affairs and external partners.\n\nProvide AD review and approval of SOPs, risk assessments, protocols and reports.\n\nProvide regular updates of AD group activities to the Chief Operating Officer and other Replimune senior management.\n\nEducational requirements:\nEducation will be appropriate to specific job requirements. The following educational requirements are a minimum:\nB.A or B.S. degree in a relevant biological science. M.S., Ph.D. or other post-graduate degree in biochemistry or related science is preferred\n\nExperience and skill requirements:\nTraining and experience will be appropriate to specific job requirements. The following categories will be assessed in each case:\n5-10 years industry experience, preferably in a cGMP Quality environment\n\nExperience working in a GMP testing environment with an understanding of regulatory requirements and trends related to analytics and product development.\n\nThorough understanding of current regulatory requirements and practical experience of QC testing in support of cGMP operations\n\nAbility to interface effectively with management and other groups or project teams\n\nComputer processing literacy and experience in statistical analysis\n\nExcellent verbal and written communication skills\n\nGood organizational skills\n\nAbout Replimune\nReplimune Group, Inc., headquartered in Woburn, MA, was founded in 2015 with the mission to transform cancer treatment by pioneering the development of a novel portfolio of oncolytic immunotherapies. Replimune’s proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. The RPx product candidates are expected to be synergistic with most established and experimental cancer treatment modalities, leading to the versatility to be developed alone or combined with a variety of other treatment options. For more information, please visit www.replimune.com.\nWe are an Equal Opportunity Employer.","description_format":"text","description_chars":4865,"description_truncated":false,"requirements":{"experience_years_min":5,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Biotechnology","Cell & Gene Therapy","Oncology Therapeutics"],"lifecycle":[{"event":"open","at":"2026-09-26T15:39:31Z"},{"event":"close","at":"2026-09-29T14:27:20Z"}],"liveness":null,"pay":null,"html_url":"https://alion.io/job/replimune-senior-scientist-analytical-development","json_url":"https://alion.io/job/replimune-senior-scientist-analytical-development.json","meta":{"generated_at":"2026-10-01T12:03:44Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","usage":{"tier":"crawler","counted_by":"address","units_charged":1,"used_today":3583,"day_limit":5000,"remaining_today":1417,"minute_limit":60,"resets_at":"2026-10-02T00:00:00Z"}}}