{"id":1630154,"url":"https://alion.io/job/signant-health-software-engineer-ai-accelerated-development","title":"Software Engineer - AI Accelerated Development","company":{"id":2374106,"name":"Signant Health","domain":"signanthealth.com","url":"https://alion.io/company/signanthealth","size_band":"1001-5000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Dayforce","truth_index":{"grade":"A","score":92,"open_postings":24,"ghost_share":0,"stale_share":0.333,"repost_share":0,"time_to_fill_p50_days":30,"computed_at":"2026-10-23T05:54:15Z"}},"role":"Backend","role_family":"Backend","seniority":"junior","employment_type":null,"work_mode":"remote","remote_scope":"stated_countries","remote_scope_basis":"board_field","remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Blue Bell, United States"],"countries":["US"],"hiring_countries":["US"],"hiring_countries_total":1,"salary":null,"salary_estimate":{"min_usd":78000,"max_usd":160000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":114},"experience_years_min":1,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Agentic Workflows","optional":false},{"name":"AI Agents","optional":false},{"name":"Anthropic","optional":false},{"name":"ASP.NET Core","optional":false},{"name":"Azure","optional":false},{"name":"C#","optional":false},{"name":"Claude","optional":false},{"name":"Claude Code","optional":false},{"name":"Function Calling","optional":false},{"name":"Hallucination","optional":false},{"name":"LLM","optional":false},{"name":"OpenAI","optional":false},{"name":"OpenAI Agents SDK","optional":false},{"name":"pgvector","optional":false},{"name":"Pinecone","optional":false},{"name":"Prompt Engineering","optional":false},{"name":"Python","optional":false},{"name":"Qdrant","optional":false},{"name":"RAG","optional":false},{"name":"Model Context Protocol","optional":true},{"name":"OWASP","optional":true},{"name":"PostgreSQL","optional":true}],"status":"live","first_seen_at":"2026-07-15T07:00:00Z","employer_posted_date":"2026-10-20","last_verified_at":"2026-10-23T23:36:54Z","board_verified":true,"closed_at":null,"days_open":100,"trust":{"level":"stale","repost_count":1,"flags":["stale"],"days_open":99},"description":"About Signant Health\nAt Signant Health, we help bring life-changing treatments to patients faster. We are a global evidence generation company that supports clinical trials with smart technology, scientific expertise, and hands-on operational support — so better data leads to better decisions in healthcare. We embrace AI and advanced technologies to enhance every aspect of what we do, from data analysis to operational efficiency.\n\nOur teams work at the intersection of science, technology, and patient experience, delivering digital solutions powered by AI innovation that make clinical trials more efficient, more accurate, and more accessible around the world. Trusted by leading pharmaceutical companies and CROs, our platforms and services support studies across more than 90 countries and have contributed to hundreds of new drug approvals. \n\nIf you are motivated by meaningful work, global impact, and innovation in clinical research and digital health — including the opportunity to work with cutting-edge AI technologies — you will find purpose and opportunity at Signant Health.\n\nAbout the Role\nSignant Health is looking for a Software Engineer – AI Accelerated Development to build AI-powered, agentic features into our clinical trial platforms. Working across the .NET stack, you will take AI capabilities from backend LLM integration through to a usable front-end — designing agents and agentic workflows, not just prompting a model. This is a hands-on engineering role for someone who works with agentic tooling every day and wants to ship production AI in a regulated, high-impact environment. We weigh the depth of your AI and agentic build experience more heavily than years of general experience: a developer with one to three years of substantive, hands-on agentic work is exactly the profile we are targeting.\nKEY ACCOUNTABILITIES – Function\nDesign and build AI agents and agentic workflows — tool-use/function calling, multi-step task orchestration, and agent loops — that power Signant Health's clinical trial platforms.\nIntegrate LLM APIs (Anthropic, OpenAI, Bedrock, or Azure OpenAI) into .NET application code, handling authentication, streaming, error handling, and cost/latency tradeoffs.\nDeliver AI features end-to-end, taking them from backend integration through to a usable, production-ready front-end.\nBuild custom agents and tools with the Claude Agent SDK, wiring and steering agent loops.\nAuthor custom skills and slash commands for Claude Code to codify team-specific workflows.\nImplement RAG pipelines and integrate vector stores (e.g. Qdrant, pgvector, Pinecone) to ground agent outputs in trusted data.\nInstrument agents for evaluation and observability so their outputs can be verified, measured, and audited.\nApply AI-specific risk controls appropriate to a regulated clinical environment, addressing hallucination, determinism, and auditability of agent decisions.\nUse Claude Code (or an equivalent agentic CLI) daily as a primary development tool, reviewing and steering AI-generated diffs.\n\nKNOWLEDGE, SKILLS & ATTRIBUTES\n\nEssential:\nFull-stack .NET development — C#/ASP.NET Core on the backend paired with a modern front-end framework.\nHands-on agentic development experience — building AI agents or agentic workflows (tool-use/function calling, multi-step task orchestration, agent loops); not just prompting an LLM, but building systems around one.\nPractical LLM API integration (Anthropic, OpenAI, Bedrock, or Azure OpenAI), including authentication, streaming, error handling, and cost/latency tradeoffs.\nProven full-stack delivery of AI features — able to take an agentic/AI feature from backend integration through to a usable front-end, not just a notebook prototype.\nDaily, hands-on use of Claude Code (or an equivalent agentic CLI) as a primary development tool — comfortable working through multi-step agentic sessions and reviewing and steering AI-generated diffs, rather than occasional autocomplete-style use.\nPrompt engineering — designing and iterating on system prompts as production software contracts, not one-off experiments.\nPython proficiency as the preferred language for AI/agent tooling; comfort with async patterns a plus.\nEvaluation and observability literacy — able to reason about whether an agent's output is correct and instrument it to prove so.\n\nDesirable:\nClaude Agent SDK experience — building custom agents, defining tools, and wiring agent loops.\nWorking knowledge of agent primitives: hooks (deterministic pre/post-tool-call controls), skills (progressive-disclosure, load-on-demand instructions), subagents/multi-agent delegation, and session/state management.\nExperience authoring custom skills or slash commands for Claude Code to codify team-specific workflows.\nExposure to MCP (Model Context Protocol) for connecting agents to internal tools and data sources.\nWorking knowledge of RAG patterns and vector store integration (e.g. Qdrant, pgvector, Pinecone).\nAwareness of AI-specific risk areas relevant to a regulated environment (OWASP LLM Top 10, hallucination/determinism concerns, and auditability of agent decisions).\nWhy Signant Health?\nAt Signant Health, your work has real impact. Everything we build, support, and deliver helps advance clinical research and bring new treatments to patients faster — improving lives around the world. Our teams combine science, technology, and operational expertise to solve complex clinical trial challenges, and every role contributes to that mission.\nWe offer a collaborative, global environment where you can grow your career while working alongside experts across clinical, technology, data, and operations, with opportunities to learn, take ownership, and drive meaningful innovation — not just maintain the status quo.\nIf you are looking for purpose-driven work, smart colleagues, and the opportunity to help shape the future of clinical research and digital health, Signant Health is the place to do it.","description_format":"text","description_chars":5943,"description_truncated":false,"requirements":{"experience_years_min":1,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":null,"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Artificial Intelligence","Clinical Trial Software","Clinical Trial Sites & Recruitment"],"lifecycle":[{"event":"open","at":"2026-10-01T21:18:44Z"},{"event":"close","at":"2026-10-14T19:44:28Z"},{"event":"reopen","at":"2026-10-20T05:55:18Z"}],"visa":[],"liveness":{"score":13,"band":"cold","label":"Long shot","p_open":1,"p_active":0.455,"p_room":0.28,"age_days":99,"expected_fill_days":30,"reasons":["conf:1","velocity","win:tail","crowd:junior"],"computed_at":"2026-10-23T05:54:15Z"},"pay":null,"html_url":"https://alion.io/job/signant-health-software-engineer-ai-accelerated-development","json_url":"https://alion.io/job/signant-health-software-engineer-ai-accelerated-development.json","meta":{"generated_at":"2026-10-24T02:06:50Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":3412,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-25T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":2374106},"rest":"https://alion.io/mcp/rest/get_company?id=2374106"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fsignant-health-software-engineer-ai-accelerated-development"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fsignant-health-software-engineer-ai-accelerated-development"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fsignant-health-software-engineer-ai-accelerated-development"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/signant-health-software-engineer-ai-accelerated-development\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fsignant-health-software-engineer-ai-accelerated-development"}]}