{"id":3034816,"url":"https://alion.io/job/smmttx-senior-manager-analytical-sciences","title":"Senior Manager, Analytical Sciences","company":{"id":21096,"name":"Summit Therapeutics","domain":"smmttx.com","url":"https://alion.io/company/smmttx","size_band":"201-500","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":null},"role":"Biotech","role_family":"Biotech","seniority":"senior","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Princeton, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":148000,"max":188000,"currency":"USD","period":"year","gross":null,"usd_annual":188000},"salary_estimate":null,"experience_years_min":5,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[],"status":"live","first_seen_at":"2026-10-19T14:51:17Z","employer_posted_date":"2026-10-19","last_verified_at":"2026-11-02T05:19:37Z","board_verified":true,"closed_at":null,"days_open":13,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":13},"description":"About Summit:\nSummit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.\nSummit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:\nNon-small Cell Lung Cancer (NSCLC)\nHARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.\n\nHARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.\n\nHARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.\n\nColorectal Cancer (CRC)\nHARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.\n\nIvonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.\nSenior Manager, Analytical Sciences\nLocation: Princeton, New Jersey\nPosition Summary\nThe Senior Manager, Analytical Sciences will provide scientific and technical leadership for analytical activities supporting biologic products from clinical development through post-approval support. This role is responsible for advancing robust analytical strategies, overseeing method development, validation, and transfer, and contributing to product characterization, comparability assessments, and regulatory submissions. The successful candidate will combine strong technical expertise with effective external partner management, sound judgment, and a flexible, hands-on approach in a dynamic development environment.\nKey Responsibilities\nLead analytical method development, qualification, validation, and transfer activities for biologic drug substances and drug products.\nDesign and oversee extended product characterization studies to establish a comprehensive understanding of product quality attributes.\nDevelop analytical strategies and execute comparability assessments supporting process changes, manufacturing changes, formulation changes, technology transfers, and product lifecycle activities.\nAuthor and critically review analytical sections of regulatory submissions and responses to health authority questions.\nEnsure analytical programs align with relevant ICH guidelines and global regulatory expectations across preclinical, clinical, registration, and post-approval stages.\nProvide scientific interpretation of analytical data, identify risks, and recommend practical, phase-appropriate solutions.\nManage contract laboratories, contract development and manufacturing organizations, and other external partners, including defining scope, monitoring timelines and deliverables, reviewing technical work, and resolving issues.\nPartner cross-functionally with Process Development, Formulation, Manufacturing, Quality, Regulatory Affairs, and other CMC functions to deliver integrated development plans.\nContribute to continuous improvement of analytical capabilities, technical standards, workflows, and documentation practices.\nDemonstrate a flexible, collaborative, and can-do attitude while responding effectively to changing priorities and business needs.\nRequired Qualifications\nBachelor’s degree in analytical chemistry, biochemistry, pharmaceutical sciences, chemical engineering, biology, or a related scientific discipline; an advanced degree is preferred.\nMinimum of 5 years of relevant experience in the biotechnology, biopharmaceutical, or pharmaceutical industry.\nDemonstrated experience with analytical method development, validation, and transfer for biologics.\nExperience with extended product characterization and comparability assessments for biologic products.\nHands-on experience authoring and reviewing analytical content for regulatory submissions.\nStrong knowledge of relevant ICH guidelines and regulatory expectations for biologics from preclinical development through post-approval support.\nProven experience managing external laboratories, vendors, or development and manufacturing partners.\nStrong scientific writing, data interpretation, problem-solving, project management, and stakeholder communication skills.\nWork Expectations\nThis position is based at the company’s Princeton, New Jersey site.\nAbility and willingness to work outside standard business hours when needed to support critical activities and global business needs.\nAbility and willingness to travel for business, including visits to external partners and manufacturing or laboratory sites.\nThis is the pay for this position\nPay Transparency\n$148,000—$188,000 USD\nActual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.\nSummit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at  to obtain prior written authorization before referring any candidates to Summit.\nSummit Therapeutics Inc. is an Equal Opportunity Employer and takes pride in creating and maintaining diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.","description_format":"text","description_chars":6765,"description_truncated":false,"requirements":{"experience_years_min":5,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Prescription Drugs","Biologics & Biosimilars","Oncology Therapeutics"],"lifecycle":[{"event":"open","at":"2026-10-21T21:09:40Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 7 · green card filings: 1","filings_12m":7,"filings_prev_12m":3,"green_card_filings_12m":1,"median_offered_wage_usd":163125,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":86,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.86,"p_room":1,"age_days":13,"expected_fill_days":60,"reasons":["conf:0","win:early"],"computed_at":"2026-11-02T06:13:15Z"},"pay":{"stated_usd_annual":188000,"is_top_pay":true},"html_url":"https://alion.io/job/smmttx-senior-manager-analytical-sciences","json_url":"https://alion.io/job/smmttx-senior-manager-analytical-sciences.json","meta":{"generated_at":"2026-11-02T08:43:45Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":12262,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-03T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":21096},"rest":"https://alion.io/mcp/rest/get_company?id=21096"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fsmmttx-senior-manager-analytical-sciences"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fsmmttx-senior-manager-analytical-sciences"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fsmmttx-senior-manager-analytical-sciences"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/smmttx-senior-manager-analytical-sciences\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fsmmttx-senior-manager-analytical-sciences"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3034816}},{"tool":"search_jobs","arguments":{"company":"smmttx.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3034816},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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