{"id":910249,"url":"https://alion.io/job/sophia-genetics-senior-software-engineer","title":"Senior Software Engineer","company":{"id":54279,"name":"SOPHiA GENETICS","domain":"sophiagenetics.com","url":"https://alion.io/company/sophia-genetics","size_band":null,"is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workable","truth_index":null},"role":"Backend","role_family":"Backend","seniority":"senior","employment_type":"full_time","work_mode":"hybrid","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Boston, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":71250,"max":143750,"currency":"USD","period":"year","gross":null,"usd_annual":143750},"salary_estimate":null,"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Apache Kafka","optional":false},{"name":"CI/CD","optional":false},{"name":"DuckDB","optional":false},{"name":"FHIR","optional":false},{"name":"GitLab","optional":false},{"name":"Grafana","optional":false},{"name":"HL7","optional":false},{"name":"Java","optional":false},{"name":"Linux","optional":false},{"name":"Loki","optional":false},{"name":"MariaDB","optional":false},{"name":"Micronaut","optional":false},{"name":"MySQL","optional":false},{"name":"React.js","optional":false},{"name":"AWS Strands Agents","optional":true},{"name":"JavaScript","optional":true}],"status":"live","first_seen_at":"2026-09-14T00:00:00Z","employer_posted_date":"2026-09-14","last_verified_at":"2026-11-08T15:37:51Z","board_verified":true,"closed_at":null,"days_open":55,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":55},"description":"Are you an experienced Software Engineer with a passion for building and improving scalable, high-performance systems? Are you looking for a team that embraces fresh ideas, encourages an agile approach, and ensures your voice is heard and your contributions truly make an impact?\nIf this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Software Engineering team as our new Senior Software Engineer, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide.\nThis is a hybrid opportunity, requiring 3 days onsite our corporate office in Boston, MA. \nOur Mission\nWe believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe.\nYour Mission\nAs a Senior Software Engineer, you will be responsible for designing, developing, optimizing, and continuously improving software solutions, while contributing to technical initiatives and ensuring the solutions meet both business and technical requirements.\nYour work will enable healthcare institutions in setting up diagnostic workflows that integrate seamlessly with the SOPHiA DDM platform - processing high-volume of medical data and bringing insights for oncologists via a streamlined process.\nThese components span the complete technology stack of SOPHiA DDM as well as the middleware layer responsible for integration and connectivity between SOPHiA DDM and external hospital systems. Your expertise will ensure these components not only scale effectively but also remain efficient in terms of performance and cost, while being extended with features required for new integrations.\nThe value you bring\nDesign, develop, and continuously improve robust services that are scalable and efficient while fitting into overall system architecture\nImplement new features and enhancements across SOPHiA DDM core components, public API as well as middleware layer to enable setup of new integrations with external hospital systems of our customers\nSupport existing live integrations with customers, propose and implement enhancements based on customer feedback and to achieve system robustness goals\nEnsure components perform reliably under high workloads, optimize system performance, resource utilization, and task execution times, contribute to improvements in system stability\nOptimize deployment workflows, automate pipelines, and enhance infrastructure management for efficient and reliable application deployment\nImplement and maintain monitoring systems to track performance and identify bottlenecks, use existing observability tools like Grafana and Loki to provide insights into operational health\nUse cutting edge AI tools and software engineering best practices to boost productivity across all workstreams\nRequirements\nMinimum of 5 years' experience in a comparable role, holding a bachelor’s or master’s degree (or higher)\nSolid proficiency in Java for backend services\nSolid understanding and extensive working experience with microservices architecture\nSolid experience with public APIs including API definition and change management\nProficiency with databases like MySQL, MariaDB, and DuckDB, including design and query optimization\nPower user of latest AI tools and agent orchestration in all stages of software life cycle\nKnowledge of HL7 and FHIR standards for healthcare data exchange is a strong plus\nFamiliarity with Linux environments and GitLab for version control and CI/CD pipelines\nExperience in optimization of system performance, manage resources effectively, and improve execution time - esp. when dealing with large data volumes\nExperience with scalable architecture, particularly in cloud environments and containerized infrastructure\nFamiliarity with monitoring and observability tools such as Grafana and Loki\nReact.js experience for front end development is a strong plus\nExperience with Micronaut for developing microservices and backend solutions is a strong plus.\nKnowledge of Kafka is a plus\nExperience in genomics is beneficial\nBenefits\nYou will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth.\nBusiness recognition and accolades include:\nWorld's most innovative companies (Top 10)\nWorld's smartest companies (Top 50) \n100 Best Places to Work in Boston \nTop 10 European Tech Startup \nTop 10 European biotechs startup to watch\nTop 25 East-Coast Biotech to watch\nOur benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview:\nUS:\nOutstanding Medical, Dental & Vision with 90% Employer Contribution\nCompany matched 401K at 4%\nCompany-paid short & long-term disability insurance\nFSA commuter benefits\n20 Days PTO, increasing to 25 with tenure; 5 Days Sick and 14 Public Holidays\nFree EAP\nOur DNA\nLike the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous\nOur Virtues\nAt SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn.\nAt the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal\nThe Process\nWe use the power of AI to help our partners make decisions. If you’re utilizing AI in your search and application process, why not use some of these prompts, or read our AI guide.\n‘What impact can I expect to have on the world by working at SOPHiA GENETICS?’\n‘I have an interview with SOPHiA GENETICS. What should I know before I meet with them?’\n‘I am a *job title* - What can SOPHiA GENETICS offer my career?’\nApply now with your CV and any supporting information.\nSuitably qualified candidates will be invited through an interview and screening process where you will speak with members of our Talent Acquisition Team, the hiring leader alongside key colleagues and stakeholders from across the business.\nIf you need additional support or accommodations for accessibility, please contact our TA team for assistance on . SOPHiA GENETICS recruiters only contact candidates from @sophiagenetics.com addresses and never request payment at any stage. Verify any offer before responding.\nWe appreciate the value external partners can bring, but we operate a direct-hiring model and we are not looking to utilize agency support at this time. All hiring is controlled by Talent Acquisition, potential partners should liaise through TA and not our hiring teams please.\nStarting Date: ASAP\nLocation: Boston, MA - Hybrid 3x/week in office\nContract: Permanent\nMA Pay Range: USD 71'250-143'750\nDisclaimer: The estimated pay range represents a good faith estimate of what the Company expects to pay a successful applicant for the listed position and applies specifically to candidates based in Massachusetts. Due to various factors, the estimated pay range may vary in other locations. Should the level or location of the role change during the hiring process, the applicable base range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual’s qualifications, job related skills, years of experience, location, relevant education or training, internal equity, and alignment with market data. 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