{"id":1931848,"url":"https://alion.io/job/strand-therapeutics-associate-scientist-ii-msat","title":"Associate Scientist II, MSAT","company":{"id":2054312,"name":"Strand Therapeutics","domain":"strandtx.com","url":"https://alion.io/company/strandtx","size_band":"11-50","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":"junior","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Boston, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":81000,"max":89000,"currency":"USD","period":"year","gross":null,"usd_annual":89000},"salary_estimate":null,"experience_years_min":2,"visa_sponsorship":false,"relocation_package":false,"has_equity":true,"technologies":[{"name":"Chromatography","optional":true},{"name":"ELISA","optional":true}],"status":"live","first_seen_at":"2026-10-05T21:19:59Z","employer_posted_date":"2026-10-05","last_verified_at":"2026-11-05T23:00:23Z","board_verified":true,"closed_at":null,"days_open":31,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":31},"description":"Company Overview:\nStrand Therapeutics is a clinical-stage biotechnology company pioneering programmable mRNA therapeutics to unlock the full potential of genetic medicines. Strand is applying its proprietary Signal Stack platform, which integrates EverScript circular RNA, AmpliScript self-replicating RNA, SignalPath targeted delivery, and logic-driven SignalLock genetic circuits to enable precise control of therapeutic activity across tissues and cell types and overcome foundational limitations in targeting, durability, and safety.\nStrand is advancing a pipeline with an initial focus on oncology and autoimmune disease. Its initial program, STX-001, an intratumorally delivered LNP-encapsulated self-replicating RNA expressing IL-12, has demonstrated preliminary evidence of systemic immune activation and anti-tumor activity in patients with advanced solid tumors who have progressed on prior therapies. Building on this early clinical validation, intravenously delivered STX-003 is designed for tumor-targeted expression and avoidance of off-target expression. STX-003, which is expected to enter the clinic in mid-2026, has the potential to be a major step forward for the fields of genetic medicine and oncology. Strand is also advancing STX-005, an in vivo CAR-T program designed to enable controlled, durable expression and repeat dosing. Founded by MIT synthetic biology pioneers, Strand has raised over $250 million and is headquartered in Boston, MA. \nBecome the next standout single strand!\nJob Summary:\nStrand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a small but extremely productive team. This opportunity will offer the employee the ability to work in a matrix-based environment and be a part of the future strategy of the company.\nWe are looking for a highly motivated and innovative candidate for the role of Associate Scientist II of MSAT. The expectation is that the Associate Scientist II will have experience prior supporting preclinical and clinical-stage manufacturing processes within the gene and/or cell therapies space. Reporting to the Senior Scientist of MSAT, the right candidate will be a strategic thinker that brings a leadership presence and enthusiasm for Strand along with a desire to conquer new challenges.\nPrimary Responsibilities:\nSupport the execution, continuous improvement, and maturation of Strand’s preclinical and clinical-stage manufacturing processes.\nPerform lab-scale RNA and lipid nanoparticle production and analytical testing to evaluate process improvements, troubleshoot technology transfer and manufacturing challenges, improve process robustness, and support process scale-up.\nAuthor technical protocols and reports documenting experimental procedures, results, and conclusions.\nCollaborate with Process Development, Analytical Development, Automation, and Quality teams to advance Strand’s manufacturing programs.\nPartner with external technical counterparts to support ongoing tech transfer and manufacturing activities.\nQualifications:\nB.S. or Advanced Degree in Biochemistry, Chemical Engineering or related field, with 2+ years of working experience in RNA and/or LNP process improvement, manufacturing and/or optimization at a biotech.\nExperience collecting, analyzing, and interpreting experimental data to evaluate process performance and support technical conclusions.\nExperience with process development, scale-up, technology transfer, manufacturing support, and process troubleshooting. Experience contributing to process characterization or later-stage development activities is a plus.\nExperience optimizing and troubleshooting enzymatic reactions, chromatographic purification, TFF, and other filtration methods for biologics.\nFamiliarity with ÄKTA systems and UNICORN control software is preferred.\nHands-on experience with RNA and/or LNP production processes and respective standard analytical methods (UV-Vis Spectroscopy, Gel Electrophoresis, ELISA, DLS, RiboGreen, etc.) strongly preferred.\nStrong technical documentation and communication skills. Ability to generate and maintain clear and detailed laboratory records, and present experimental designs, data interpretation, and conclusions to cross-functional groups.\nStrand offers a fast-paced, entrepreneurial, team-focused small company environment. We also offer a top-notch benefits package (health, dental, life, open PTO, onsite lunch catering, commuter support and more) and work/life flexibility and integration. Being part of the Strand team allows you to become part of a small team that supports professional development while working together to meet Strand’s goals. \nStrand Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Strand does not accept unsolicited resumes from any source other than directly from candidates.\nJob Type: Full-time\nSalary: $81,000 - $89,000 annually plus bonus and equity incentives\nPay Transparency Base Salary Range\n$81,000—$89,000 USD","description_format":"text","description_chars":5188,"description_truncated":false,"requirements":{"experience_years_min":2,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":null,"security_clearance":false,"languages":[]},"benefits":["Equity","Professional development"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Oncology Therapeutics"],"lifecycle":[{"event":"open","at":"2026-10-05T22:12:23Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 9 · green card filings: 1","filings_12m":9,"filings_prev_12m":7,"green_card_filings_12m":1,"median_offered_wage_usd":83500,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":40,"band":"fade","label":"Fading","p_open":1,"p_active":0.721,"p_room":0.55,"age_days":30,"expected_fill_days":24,"reasons":["conf:3","win:tail","comp:junior"],"computed_at":"2026-11-05T05:54:30Z"},"pay":{"stated_usd_annual":89000,"is_top_pay":true},"html_url":"https://alion.io/job/strand-therapeutics-associate-scientist-ii-msat","json_url":"https://alion.io/job/strand-therapeutics-associate-scientist-ii-msat.json","meta":{"generated_at":"2026-11-06T01:13:41Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":1991,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-07T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":2054312},"rest":"https://alion.io/mcp/rest/get_company?id=2054312"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fstrand-therapeutics-associate-scientist-ii-msat"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fstrand-therapeutics-associate-scientist-ii-msat"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fstrand-therapeutics-associate-scientist-ii-msat"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/strand-therapeutics-associate-scientist-ii-msat\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fstrand-therapeutics-associate-scientist-ii-msat"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":1931848}},{"tool":"search_jobs","arguments":{"company":"strandtx.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":1931848},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. Docs: https://alion.io/developers"}}