{"id":4269782,"url":"https://alion.io/job/strand-therapeutics-co-op-mrna-process-development","title":"Co-op, mRNA Process Development","company":{"id":2054312,"name":"Strand Therapeutics","domain":"strandtx.com","url":"https://alion.io/company/strandtx","size_band":"11-50","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":{"grade":"B","score":75,"open_postings":3,"ghost_share":0,"stale_share":1,"repost_share":0,"time_to_fill_p50_days":null,"computed_at":"2026-11-12T10:38:37Z"}},"role":"Industrial Engineering","role_family":"Industrial Engineering","seniority":null,"employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Boston, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":25,"max":28,"currency":"USD","period":"hour","gross":null,"usd_annual":56000},"salary_estimate":null,"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Chromatography","optional":false}],"status":"live","first_seen_at":"2026-11-13T15:23:12Z","employer_posted_date":"2026-11-13","last_verified_at":"2026-11-13T17:26:55Z","board_verified":true,"closed_at":null,"days_open":0,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":0},"description":"Company Overview:\nStrand Therapeutics is a clinical-stage biotechnology company pioneering programmable mRNA therapeutics to unlock the full potential of genetic medicines. Strand is applying its proprietary Signal Stack platform, which integrates EverScript circular RNA, AmpliScript self-replicating RNA, SignalPath targeted delivery, and logic-driven SignalLock genetic circuits to enable precise control of therapeutic activity across tissues and cell types and overcome foundational limitations in targeting, durability, and safety.\nStrand is advancing a pipeline with an initial focus on oncology and autoimmune disease. Its initial program, STX-001, an intratumorally delivered LNP-encapsulated self-replicating RNA expressing IL-12, has demonstrated preliminary evidence of systemic immune activation and anti-tumor activity in patients with advanced solid tumors who have progressed on prior therapies. Building on this early clinical validation, intravenously delivered STX-003 is designed for tumor-targeted expression and avoidance of off-target expression. STX-003, which is expected to enter the clinic in mid-2026, has the potential to be a major step forward for the fields of genetic medicine and oncology. Strand is also advancing STX-005, an in vivo CAR-T program designed to enable controlled, durable expression and repeat dosing. Founded by MIT synthetic biology pioneers, Strand has raised over $250 million and is headquartered in Boston, MA. \nBecome the next standout single strand!\nJob Summary:\nStrand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a small but extremely productive team. This opportunity will offer the employee the ability to work in a matrix-based environment and be a part of the future strategy of the company.\nWe are looking for a highly motivated candidate to join as Co-op of the mRNA Process Development team at Strand Therapeutics to support the development, optimization, and scale-up of manufacturing processes for high-quality mRNA therapeutics. This role will provide hands-on experience with mRNA production, purification, analytical characterization, and process improvement activities in a collaborative and fast-paced biotechnology environment.\nPrimary Responsibilities:\nExecute experiments related to the advancement of Strands mRNA manufacturing and/or process optimization platforms.\nCarry out the production of IVT synthesized mRNA.\nSupport screening, optimization, and scale-up efforts for enzymatic reactions, chromatographic separations and filtration processes - including ultrafiltration, diafiltration, and sterile filtration.\nPerform analytical assays and characterization studies to evaluate mRNA quality and process performance.\nAnalyze experimental data and contribute to technical presentations, reports, and team discussions.\nMaintain accurate and detailed experimental records in electronic laboratory notebooks.\nWork effectively to support the group's development activities in a fast-paced and collaborative environment.\nQualifications:\nCurrently pursuing a B.S. or M.S. in Biochemistry, Chemical Engineering, Molecular Biology, Bioengineering, Molecular Medicine, Genetics or related field. Experience in the biotechnology space is a plus.\nExperience with nucleic acid workflows, chromatography, filtration processes, or biological analytic techniques is preferred, but not required\nAbility to follow standard operating procedures, make careful observations, maintain clear and complete records of lab work.\nStrong collaboration and inter-personal skills. Ability to present scientific context, experimental set up, data interpretation, and big-picture conclusions to a diverse audience.\nStrand Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. 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