{"id":3530373,"url":"https://alion.io/job/takeda-pharmaceutical-engineer-ii-downstream-process-development","title":"Engineer II, Downstream Process Development","company":{"id":5984,"name":"Takeda Pharmaceutical","domain":"takeda.com","url":"https://alion.io/company/takeda","size_band":"5000+","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"A","score":87,"open_postings":51,"ghost_share":0,"stale_share":0.49,"repost_share":0.02,"time_to_fill_p50_days":26,"computed_at":"2026-11-02T06:13:15Z"}},"role":"Industrial Engineering","role_family":"Industrial Engineering","seniority":"middle","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Lexington, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":71800,"max":112860,"currency":"USD","period":"year","gross":null,"usd_annual":112860},"salary_estimate":null,"experience_years_min":2,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Chromatography","optional":false}],"status":"live","first_seen_at":"2026-10-30T15:50:43Z","employer_posted_date":"2026-10-30","last_verified_at":"2026-11-02T10:35:12Z","board_verified":true,"closed_at":null,"days_open":2,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":2},"description":"By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.\nJob Description\nJoin Takeda as a Engineer II, Downstream Process Development. As an early-career professional, you handle problems of limited scope and complexity, adhering to established policies and procedures. Your decision-making is within a defined scope, using standardized methods to analyze situations and data. You are developing knowledge of basic principles, theories, and concepts, and beginning to apply industry practices and standards. Typically, this role requires some relevant experience, with contributions mostly related to task-specific activities. Your primary contacts are with your immediate team, and you work under moderate direction and close supervision, following specific, detailed instructions.\nAbout the role:\nThe Process Development Engineer is responsible for supporting downstream biotherapeutics process development through hands-on purification and recovery development experiments. This individual contributor role supports process development across multiple scales, from micro scale through bench and pilot scale, and contributes to both early-stage and late-stage programs. You will work in teams with more senior process engineers to collaboratively execute larger experiments, while also working closely with process development team members to generate data, maintain accurate records, and contribute to the development and optimization of downstream processes.\nHow you will contribute:\nExecute chromatography, harvest operations, ultrafiltration and diafiltration (UF/DF), and viral clearance experiments with additional potential support of bioconjugation.\nSupport downstream process development across micro scale, bench scale, and pilot scale studies\nHelp maintain laboratory equipment and support routine readiness of instruments used in process development work\nWork with more senior process engineers to collaboratively plan and execute larger experiments and study activities\nDocument experimental work in electronic laboratory notebooks and maintain clear, complete, and timely records\nPerform basic data analysis to review trends, compare conditions, and support study conclusions\nPrepare technical summaries, study updates, and other written materials to share results and findings\nFollow established laboratory and process development procedures, including quality and safety requirements\nContribute to continuous improvement efforts by identifying ways to improve workflows, data capture, and experimental execution\nAssist with small projects or specific project tasks under close supervision What you bring to Takeda:\nAssociate degree with 2+ years of relevant experience, or bachelor’s degree with relevant experience, in chemical engineering, chemistry, biochemistry, biotechnology, or a related field\nExperience with chromatography, harvest, ultrafiltration and diafiltration, and viral clearance steps\nComfort with emerging digital tools and openness to AI-enabled processes that support data analysis, documentation, and workflow improvement.\nExperience with basic bioprocess control systems\nExperience using electronic laboratory notebooks for study documentation/data entry\nAbility to perform basic data analysis and present results clearly in written form\nFamiliarity with technical writing for laboratory reports or development documents\nUnderstanding of laboratory practices, process development methods, and quality requirements\nAbility to follow detailed procedures, maintain accurate records, and work under close supervision\nSome relevant experience in process development, protein purification, or a related laboratory setting\nImportant Considerations:\nAt Takeda, our patients rely on us to deliver quality products. As a result, we must follow strict rules in our manufacturing facilities to ensure we are not endangering the quality of the product. In this role, you may:\nWork in a controlled environment requiring special gowning and wear protective clothing over the head, face, hands, feet and body. This may include additional hearing protection for loud areas.\nNeed to remove all make-up, jewelry, contact lenses, nail polish and/or artificial fingernails while in the manufacturing environment.\nWork in a cold, wet environment.\nWork multiple shifts, including weekends, or be asked to work supplemental hours, as necessary.\nWork around chemicals such as alcohol, acids, buffers and Celite that may require respiratory protection.\nMore about us:\nAt Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.\nCertified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.\n#GMSGQ #ZR1 #LI-MA1\nTakeda Compensation and Benefits Summary\nWe understand compensation is an important factoras you consider the next step in your career. We are committed to equitablepay for all employees, and we strive to be more transparent with our pay practices.\nFor Location:\nLexington, MAU.S. Base Salary Range:\n$71,800.00 - $112,860.00The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.\nFor information about our benefits, please click here.\nEEO Statement\nTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.\nLocations\nLexington, MAWorker Type\nEmployeeWorker Sub-Type\nRegularTime Type\nFull timeJob Exempt\nYesIt is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.","description_format":"text","description_chars":7244,"description_truncated":false,"requirements":{"experience_years_min":2,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"associate","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Prescription Drugs","Oncology Therapeutics","Neurology & CNS Therapeutics","Rare Disease Therapeutics"],"lifecycle":[{"event":"open","at":"2026-10-30T15:50:43Z"}],"visa":[],"liveness":{"score":90,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.903,"p_room":1,"age_days":2,"expected_fill_days":26,"reasons":["conf:6","velocity","win:early","comp:brand"],"computed_at":"2026-11-02T06:13:15Z"},"pay":{"stated_usd_annual":112860,"is_top_pay":true},"html_url":"https://alion.io/job/takeda-pharmaceutical-engineer-ii-downstream-process-development","json_url":"https://alion.io/job/takeda-pharmaceutical-engineer-ii-downstream-process-development.json","meta":{"generated_at":"2026-11-02T13:25:06Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":18250,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-03T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":5984},"rest":"https://alion.io/mcp/rest/get_company?id=5984"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Ftakeda-pharmaceutical-engineer-ii-downstream-process-development"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Ftakeda-pharmaceutical-engineer-ii-downstream-process-development"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Ftakeda-pharmaceutical-engineer-ii-downstream-process-development"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/takeda-pharmaceutical-engineer-ii-downstream-process-development\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Ftakeda-pharmaceutical-engineer-ii-downstream-process-development"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3530373}},{"tool":"search_jobs","arguments":{"company":"takeda.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3530373},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. Docs: https://alion.io/developers"}}