{"id":3628824,"url":"https://alion.io/job/tango-therapeutics-clinical-trials-manager","title":"Clinical Trials Manager","company":{"id":686675,"name":"Tango Therapeutics","domain":"tangotherapeutics.com","url":"https://alion.io/company/tangotherapeutics","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":null},"role":"Biotech","role_family":"Biotech","seniority":"senior","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Boston, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":120000,"max":180000,"currency":"USD","period":"year","gross":null,"usd_annual":180000},"salary_estimate":null,"experience_years_min":5,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"GCP","optional":false},{"name":"Good Clinical Practice","optional":false}],"status":"live","first_seen_at":"2026-08-14T13:51:49Z","employer_posted_date":"2026-11-02","last_verified_at":"2026-11-14T01:19:36Z","board_verified":true,"closed_at":null,"days_open":91,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":91},"description":"Company Overview\nTango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.\nUsing an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.\nThis includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.\nThe Tango labs and offices are located at 201 Brookline Avenue, inthe Fenway area of Boston, Massachusetts\nSummary\nWe are seeking a Clinical Trial Manager (CTM) to lead operational aspects of a clinical trial and support the Clinical Trial Leader (CTL), as required. This role will serve as a key member of the Clinical Trial Team (CTT) and as the primary contact for external parties and vendors. CTM may lead the cross-functional CTT for smaller and less complex trials or manage critical aspects of larger and more complex clinical trials under CTL leadership. In addition, CTM will be responsible for site management oversight for trials where no Site Management Leader (SML) is assigned.\nIn a fast-paced, small biotech environment, the CTM will operationally manage the set-up, conduct and reporting of clinical trials (or parts thereof) as per approved timelines, budget, regulatory requirements, and internal standards. This individual will play a key role in the execution and delivery of clinical trial objectives.\nThe ideal candidate is highly collaborative, detail-oriented, and comfortable operating in a hands-on environment, with a focus on building scalable processes, tools, and best practices to support efficient and compliant clinical trial execution.\nYour Role:\nServe as a core member of the Clinical Trial Team (CTT) and act as deputy for the Clinical Trial Leader (CTL) during absences\nOrganize and coordinate CTT meetings, including preparing agendas, recording minutes, and tracking follow-up actions\nFacilitate communication and collaboration within the team and with external partners such as Contract Research Organizations (CROs) and vendors\nContribute to the development and maintenance of trial-level documents and operational plans, including project management, communication, risk management, and quality plans\nEstablish and manage trial-related systems and processes (e.g., central laboratories, eCOA/ ePRO) in alignment with protocol requirements\nMonitor CRO/ vendor performance and ensure timely and accurate data integration, transfer, and reconciliation. Escalate issues to the CTL, as needed\nIdentify risks and issues and support the development and implementation of mitigation strategies and action plans\nMaintain accurate and up-to-date trial information in systems and communication tools\nSet up and maintain clinical trial insurance in participating countries\nCoordinate with the global supply chain to ensure timely supply and distribution of devices and investigational medicinal products, comparator or co-medication to clinical sites\nPrepare and distribute trial-related correspondence and contribute to the development of materials for meetings, newsletters, and websites\nLead logistical arrangements and support content development for external meetings such as investigator meetings and advisory boards\nEnsure ongoing inspection and audit readiness. Participate in internal audits and regulatory inspections, as required\nSupport budget forecasting and accrual processes. Assist with invoice tracking, and processing in line with vendor contracts\nAct as CTL when assigned, leading cross-functional CTT to operationalize the protocol of a clinical trial\nLead the development of site management oversight plan and ensure site management oversight including risk management for trials without assigned Site Management Lead (SML)\nWhat You Bring: \n5+ years of trial management experience. Leadership experience (preferred)\nBachelor’s degree in Life Sciences, Pharmacy or related field\nExperience working in global clinical development organization\nExperience in Oncology development (preferred)\nDirect experience with health authority inspections (FDA, EMA, MHRA, etc.) incl. sponsor GCP inspections (preferred)\nExperience in outsourcing and oversight\nKnowledge of ICH-GCP, FDA guidelines, EU CTR and other relevant guidelines\nKnowledge of financial planning, tracking, and reporting\nKnowledge of trial risk assessment and management\nFamiliarity with clinical trial systems (e.g., CTMS, eTMF, EDC, IRT, eCOA) and site management metrics, KPIs, and KRIs\nStrong vendor management and project management skills\nLeadership skills with the ability to lead cross-functional teams\nStrong interpersonal and communication skills\nStrong analytical thinking and decision-making capabilities\nWillingness to travel, as required (typically 10-20%)\nWe are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.\nSalary range\n$120,000—$180,000 USD","description_format":"text","description_chars":5242,"description_truncated":false,"requirements":{"experience_years_min":5,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Biotechnology","Precision Medicine","Oncology Therapeutics"],"lifecycle":[{"event":"open","at":"2026-11-02T20:22:40Z"}],"visa":[{"country":"US","licensed_sponsor":true,"adverts_offering_sponsorship_24m":0,"sanctioned_now":false,"evidence":"H-1B filings in 12 months: 3","filings_12m":3,"filings_prev_12m":2,"green_card_filings_12m":0,"median_offered_wage_usd":497500,"route":null,"cap_exempt":false,"checked_at":"2026-11-12T07:36:15+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)"],"filings_for_role_12m":0}],"liveness":{"score":26,"band":"fade","label":"Fading","p_open":1,"p_active":0.736,"p_room":0.36,"age_days":89,"expected_fill_days":55,"reasons":["conf:5","win:tail","crowd:"],"computed_at":"2026-11-12T10:38:37Z"},"pay":{"stated_usd_annual":180000,"is_top_pay":false},"html_url":"https://alion.io/job/tango-therapeutics-clinical-trials-manager","json_url":"https://alion.io/job/tango-therapeutics-clinical-trials-manager.json","meta":{"generated_at":"2026-11-14T05:08:03Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":8536,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-15T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.1,"usd":0.01,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":686675},"rest":"https://alion.io/mcp/rest/get_company?id=686675"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Ftango-therapeutics-clinical-trials-manager"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"free","price":{"credits":0,"usd":0},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Ftango-therapeutics-clinical-trials-manager"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.1,"usd":0.01},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Ftango-therapeutics-clinical-trials-manager"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/tango-therapeutics-clinical-trials-manager\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Ftango-therapeutics-clinical-trials-manager"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3628824}},{"tool":"search_jobs","arguments":{"company":"tangotherapeutics.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3628824},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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