{"id":1562324,"url":"https://alion.io/job/topos-bio-cellular-biologist","title":"Cellular Biologist","company":{"id":2309199,"name":"Topos Bio","domain":"toposbio.ai","url":"https://alion.io/company/toposbio","size_band":"11-50","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Ashby","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":null,"employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["South San Francisco, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":79000,"max_usd":219000,"period":"year","method":"role_country_seniority_unknown","sample_n":2038},"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[],"status":"live","first_seen_at":"2026-09-30T03:12:19Z","employer_posted_date":"2026-09-30","last_verified_at":"2026-10-01T18:03:40Z","board_verified":true,"closed_at":null,"days_open":1,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":1},"description":"Topos Bio\nAt Topos Bio, we're pioneering drug discovery for intrinsically disordered proteins-targets that have eluded conventional approaches in neurodegeneration, oncology, and cardiometabolic disease.\nWe're seeking a cell biologist to develop and execute cell-based assays for validating computational predictions and supporting medicinal chemistry efforts. You'll work at the interface of disease biology, protein biophysics, and drug screening.\nWhat you will do\nDevelop and optimize mammalian cell-based assays for disordered protein targets\n\nExecute phenotypic and reporter-based screening campaigns to validate computational hits\n\nCharacterize compound activity and support structure-activity relationship studies\n\nCollaborate with computational scientists to integrate experimental data with modeling workflows\n\nEstablish robust assay protocols and quality control metrics\n\nWhat we are looking for\nStrong foundation in mammalian cell culture and cellular assay development\n\nExperience with disease-relevant cellular models\n\nAbility to troubleshoot complex biological systems and optimize experimental protocols\n\nTrack record of productivity and effective collaboration\n\nPreferred\nPhD in cell and molecular biology with focus on disease models\n\nIndustry experience in drug discovery or biotech\n\nExperience with reporter assays and high-throughput screening platforms\n\nFamiliarity with oncology, neurodegeneration, or metabolic disease models\n\nTrack record of developing novel cellular assays or screening approaches","description_format":"text","description_chars":1522,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Artificial Intelligence","Drug Discovery","Medical AI"],"lifecycle":[{"event":"open","at":"2026-10-01T04:29:08Z"}],"liveness":{"score":86,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.86,"p_room":1,"age_days":1,"expected_fill_days":96,"reasons":["conf:1","win:early"],"computed_at":"2026-10-01T05:45:00Z"},"pay":null,"html_url":"https://alion.io/job/topos-bio-cellular-biologist","json_url":"https://alion.io/job/topos-bio-cellular-biologist.json","meta":{"generated_at":"2026-10-02T03:08:27Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","usage":{"tier":"crawler","counted_by":"address","units_charged":1,"used_today":4332,"day_limit":5000,"remaining_today":668,"minute_limit":60,"resets_at":"2026-10-03T00:00:00Z"}}}