{"id":3368282,"url":"https://alion.io/job/twist-bioscience-manufacturing-supervisor-ngs-te-production","title":"Manufacturing Supervisor, NGS TE Production","company":{"id":1814479,"name":"Twist Bioscience","domain":"twistbioscience.com","url":"https://alion.io/company/twistbioscience","size_band":"201-500","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":{"grade":"B","score":76,"open_postings":8,"ghost_share":0,"stale_share":0.875,"repost_share":0.125,"time_to_fill_p50_days":37,"computed_at":"2026-11-14T05:58:10Z"}},"role":"Industrial Engineering","role_family":"Industrial Engineering","seniority":"senior","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["South San Francisco, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":119000,"max_usd":224000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":6333},"experience_years_min":5,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"CAPA","optional":false},{"name":"GLP","optional":false},{"name":"GMP","optional":false},{"name":"ISO 13485","optional":false},{"name":"Next-Generation Sequencing","optional":false},{"name":"PCR","optional":false},{"name":"LIMS","optional":true}],"status":"live","first_seen_at":"2026-10-27T20:13:30Z","employer_posted_date":"2026-10-27","last_verified_at":"2026-11-14T20:52:39Z","board_verified":true,"closed_at":null,"days_open":18,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":18},"description":"The Manufacturing Supervisor, NGS TE Production will bring strong knowledge of synthetic and molecular biology techniques, including PCR, vector production, cloning, miniprep, DNA analysis, sequencing, and packaging. In this role, you’ll perform, train, and oversee production staff on molecular biology workflows in a highly automated, high-throughput environment, and you’ll be responsible for manufacturing and analyzing a variety of custom gene products across Twist Bioscience’s proprietary workflow according to SOPs and the daily production schedule.\nAs the main point of contact for shift operators, you’ll make sure the shift team is working to the plan of record, provide guidance, set priorities, and lead troubleshooting. You’ll also lead the pass-down of information between shifts.\nThe ideal candidate works independently, is highly organized, has excellent molecular biology skills, maintains and builds 5S systems, contributes to process improvement and documentation, and communicates effectively with peers and management. You’ll have knowledge of good laboratory practices (GLPs), familiarity with GMP or ISO-rated production, and experience leading and training others. You must be comfortable working in a LEAN manufacturing, controlled laboratory environment.\nShift 2B: Wednesday-Friday w/alt Saturday 7:00pm-7:30am\nWhat You’ll Be Doing\nManufacture high-quality custom gene products in a high-throughput manufacturing lab according to established SOPs\nMaintain thorough, accurate, and detailed documentation of all work in batch records, databases, or other approved formats, including problems and deviations\nOperate semi-automated and automated lab equipment for molecular biology workflows\nTrack metrics on product quality using both physical and functional test methods\nApply scientific principles to problem-solve and troubleshoot test results\nProactively identify production problems and recommend solutions for lab techniques, protocols, processes, and product and equipment handling\nUphold standards defined by the manufacturing process\nSupport continuous cost and process improvement initiatives\nWork safely at all times\nMaintain and calibrate select lab equipment\nLead shift pass-down efforts and prioritize workflows\nTake accountability for the shift when senior personnel are not on site\nAdvise on meeting schedules and resolving technical problems, and provide production guidance to junior manufacturing staff\nSchedule staff\nReview and verify production batch records and manufacturing documents\nWrite and submit incident reports, CAPAs, planned deviations, and related documentation\nFollow regulatory and ISO 13485 requirements\nWhat You’ll Bring to the Team\nA.S. or B.S. in Biology, Chemistry, or Biochemistry\nMinimum of 5 years of lab experience in a manufacturing environment\nExperience operating liquid handlers such as Hamilton and Tecan\nExperience with instrumentation for PCR, cell-based cloning, miniprep extraction, and purification is a huge plus\nExperience with sample tracking software and with interfaces between robotic instrumentation and LIMS/MES systems\nExperience working in ISO, GMP, and LEAN manufacturing environments and applying lean manufacturing concepts\nExcellent scientific computation and data analysis skills\nExperience assessing current processes and techniques and implementing procedural improvements\nExperience leading small teams in a laboratory environment\nStrong problem-solving and communication skills\nAbility to stand for long periods while performing duties\nAbility to work safely with chemicals and hazardous materials\nAbility to lift up to 20 lbs\nAbility to work outside regular hours or a flexible shift as needed\nAbout Twist Bioscience\nTwist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.\nAt Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.\nTwist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.\nThe base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensationamounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensationmay be different in other locations.\nSan Francisco Bay Area Pay Range\n$45—$50 USD","description_format":"text","description_chars":5017,"description_truncated":false,"requirements":{"experience_years_min":5,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":null,"security_clearance":false,"languages":[]},"benefits":["Equity"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Genomics & Genetic Testing","Molecular Diagnostics","Synthetic Biology"],"lifecycle":[{"event":"open","at":"2026-10-27T23:56:54Z"}],"visa":[{"country":"US","licensed_sponsor":true,"adverts_offering_sponsorship_24m":0,"sanctioned_now":false,"evidence":"H-1B filings in 12 months: 15 · green card filings: 5","filings_12m":15,"filings_prev_12m":20,"green_card_filings_12m":5,"median_offered_wage_usd":133750,"route":null,"cap_exempt":false,"checked_at":"2026-11-14T07:33:33+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":76,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.842,"p_room":0.9,"age_days":17,"expected_fill_days":37,"reasons":["conf:4","win:mid"],"computed_at":"2026-11-14T05:58:10Z"},"pay":null,"html_url":"https://alion.io/job/twist-bioscience-manufacturing-supervisor-ngs-te-production","json_url":"https://alion.io/job/twist-bioscience-manufacturing-supervisor-ngs-te-production.json","meta":{"generated_at":"2026-11-15T00:19:15Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":589,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-16T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.1,"usd":0.01,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":1814479},"rest":"https://alion.io/mcp/rest/get_company?id=1814479"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Ftwist-bioscience-manufacturing-supervisor-ngs-te-production"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"free","price":{"credits":0,"usd":0},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Ftwist-bioscience-manufacturing-supervisor-ngs-te-production"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.1,"usd":0.01},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Ftwist-bioscience-manufacturing-supervisor-ngs-te-production"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/twist-bioscience-manufacturing-supervisor-ngs-te-production\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Ftwist-bioscience-manufacturing-supervisor-ngs-te-production"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3368282}},{"tool":"search_jobs","arguments":{"company":"twistbioscience.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3368282},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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