{"id":1596601,"url":"https://alion.io/job/uniqure-associate-manager-internal-controls","title":"Associate Manager, Internal Controls","company":{"id":2079697,"name":"uniQure","domain":"uniqure.com","url":"https://alion.io/company/uniqure-com","size_band":null,"is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":null},"role":"Management","role_family":"Management","seniority":"junior","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Amsterdam, Netherlands"],"countries":["NL"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":40000,"max_usd":96000,"period":"year","method":"global_role_cell_scaled_by_country","sample_n":922},"experience_years_min":5,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"GDPR","optional":false}],"status":"live","first_seen_at":"2026-09-22T16:19:29Z","employer_posted_date":"2026-09-22","last_verified_at":"2026-10-04T23:06:51Z","board_verified":true,"closed_at":null,"days_open":12,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":12},"description":"Place in the Organization\nAt uniQure, we are delivering on the promise of gene therapy and delivering hope for patients facing urgent unmet medical needs. Every role in our organization carries profound purpose; whether you're in research, operations, access, or support, your contributions impact patients. We're seeking passionate professionals who thrive in high-stakes environments, uphold rigorous quality standards, and share our relentless commitment to transforming the lives of patients. Join us in making the impossible possible, where your expertise becomes a catalyst for life-changing treatments.\nPosition Overview\nThe Associate Manager, Internal Controls is a key member of the Technical Accounting and Internal Control function, reporting to the Director, Technical Accounting and Internal Control. The role is responsible for managing and executing the company’s Sarbanes-Oxley (SOX) compliance program. This role will design, test, and monitor internal controls over financial reporting (ICFR), coordinate with external auditors, and drive maturation of the control environment across a growing, multi-entity, multi-system organization (including SAP S/4HANA Public Cloud and Optro/AuditBoard). The role operates in a dual US GAAP/IFRS reporting environment subject to SEC reporting and SOX 404(b) requirements.\nKey result areas (major duties, accountabilities and responsibilities\nSOX Program Management\nOwn and manage the annual SOX compliance calendar, including scoping, risk assessment, control walkthroughs, and testing.\nMaintain and continuously improve the SOX risk and control matrix (RCM) across financial reporting, IT general controls (ITGC), and business process controls.\nCoordinate quarterly and annual control certifications with process and control owners.\nControl Design & Testing\nLead design and operating effectiveness testing of key controls, including entity-level controls, process-level controls, and ITGCs.\nIdentify control gaps and deficiencies; partner with process owners to develop and track remediation plans.\nEvaluate the severity of control deficiencies and support management's assessment of ICFR effectiveness.\nSAP & Systems Controls\nPartner with IT and Finance teams on change management, access controls, segregation of duties (SoD), and automated/application controls within SAP S/4HANA Public Cloud and related systems.\nLead control design and risk assessment for new system implementations, upgrades, and process changes, including pre- and post-go-live control validation.\nSOX Technology & Tools\nDrive improvement and increased adoption of Optro (AuditBoard) as the company's SOX/controls management platform, including workflow optimization, control owner training, and expanding usage across process and control owners.\nPartner with process owners and IT to streamline control documentation, testing, and evidence collection within Optro (AuditBoard).\nIdentify opportunities to automate manual testing procedures and reporting through the platform, reducing cycle time and improving audit-readiness.\nStakeholder & Audit Coordination\nServe as a key liaison with external auditors on SOX-related matters, including PBC requests, testing walkthroughs, and issue resolution.\nPartner cross-functionally with Accounting Operations, Financial Reporting, IT, and business process owners to embed a strong controls culture.\nPrepare materials and updates for management and Audit Committee reporting as needed.\nContinuous Improvement\nMonitor changes in regulatory requirements (SEC, PCAOB, COSO framework) and assess impact on the SOX program.\nDrive process and control efficiencies, including automation of controls and testing procedures where possible.\nSupport broader internal control initiatives, including policy development and training.\nQualifications & Skills\n\nRequired:\nBachelor’s degree in Accounting, Finance, or related field; CPA or CIA required; CISA a plus.\n5+ years of relevant experience, including at least 2 years of Big 4 public accounting experience (external audit with SOX 404(b) engagements).\nStrong working knowledge of SOX requirements, COSO framework, and ICFR testing methodologies.\nExperience with ERP systems (SAP S/4HANA preferred) and ITGC/SoD concepts; hands-on experience with AuditBoard or similar SOX/GRC.\nExcellent project management skills with the ability to manage multiple workstreams and deadlines.\nStrong communication skills, with the ability to work effectively with cross-functional and international teams.\nExperience working in a multinational, SEC-registered, or dual-listed (US/EU) company is strongly preferred.\nLife sciences, biotech, or pharmaceutical industry, preferably including pre-commercial or commercialization-stage operations is beneficial.\nWorking knowledge of US GAAP and IFRS reporting environments (this role operates in both frameworks simultaneously).\nExperience leading or co-leading internal controls through company growth phases (e.g., first commercial launch, M&A integration, ERP go-live).\n\nuniQure is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, sexual orientation, or gender identity), national origin, age, disability, genetic information, marital status, veteran or military status, or any other characteristic protected by applicable federal, state, or local laws. If you need assistance or a reasonable accommodation during the application process, please contact .\n uniQure posts all open positions exclusively on our official Careers page and LinkedIn. We do not recruit through any other job boards, third-party websites, or unsolicited outreach via text or messaging apps. All legitimate communication from uniQure’s Talent Acquisition team will come from an @uniqure.com email address. We will never request financial information nor payment of any kind during the application process. If you receive suspicious outreach claiming to be from uniQure, do not respond or share personal information. Inquiries can be made via .\nuniQure processes personal data submitted through this application for recruitment and hiring purposes only. Depending on your location, you may have specific rights regarding your personal data. For full details on how we collect, use, store, and protect your information - including disclosures for California residents under the CCPA and for applicants under the GDPR - please review our applicant privacy notice.","description_format":"text","description_chars":6534,"description_truncated":false,"requirements":{"experience_years_min":5,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Biotechnology","Cell & Gene Therapy","Genomics & Genetic Testing"],"lifecycle":[{"event":"open","at":"2026-10-01T18:04:42Z"}],"visa":[],"liveness":{"score":55,"band":"ok","label":"Likely open","p_open":1,"p_active":0.727,"p_room":0.75,"age_days":11,"expected_fill_days":16,"reasons":["conf:1","win:late","comp:junior"],"computed_at":"2026-10-04T05:45:00Z"},"pay":null,"html_url":"https://alion.io/job/uniqure-associate-manager-internal-controls","json_url":"https://alion.io/job/uniqure-associate-manager-internal-controls.json","meta":{"generated_at":"2026-10-05T00:11:14Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","usage":{"tier":"crawler","counted_by":"address","units_charged":1,"used_today":108,"day_limit":5000,"remaining_today":4892,"minute_limit":60,"resets_at":"2026-10-06T00:00:00Z"}}}