{"id":3836641,"url":"https://alion.io/job/vertex-pharmaceuticals-portfolio-program-management-associate-director","title":"Portfolio & Program Management Associate Director","company":{"id":5871,"name":"Vertex Pharmaceuticals","domain":"vrtx.com","url":"https://alion.io/company/vrtx","size_band":"5000+","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"A","score":86,"open_postings":28,"ghost_share":0,"stale_share":0.571,"repost_share":0,"time_to_fill_p50_days":38,"computed_at":"2026-11-10T06:52:35Z"}},"role":"Sales","role_family":"Sales","seniority":"head","employment_type":"full_time","work_mode":"hybrid","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Boston, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":162200,"max":243200,"currency":"USD","period":"year","gross":null,"usd_annual":243200},"salary_estimate":null,"experience_years_min":8,"visa_sponsorship":false,"relocation_package":false,"has_equity":true,"technologies":[],"status":"live","first_seen_at":"2026-11-05T21:14:50Z","employer_posted_date":"2026-11-05","last_verified_at":"2026-11-10T07:34:51Z","board_verified":true,"closed_at":null,"days_open":4,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":4},"description":"Job Description\nPosition Summary: \nThe Associate Director (AD) of Portfolio and Program Management (PPM) sits within the COO’s organization at Vertex and leads programs from Research through early Development. This role will support program teams involved in early research through to candidate preclinical development. The AD will partner with program leads and cross-functional teams to establish cross-functional strategy and plans to ensure execution against program goals.\nKey Duties and Responsibilities: \nSupport disease strategy development within Research and drive cross-functional decision-making across the drug research and early development lifecycle, ensuring alignment between scientific objectives, portfolio priorities, and organizational goals\nIn partnership with the program leader guide research and development (R&D) efforts to establish a high performing and data-driven team that delivers on corporate objectives and priorities.\nSupport defining the approach and identifying key stakeholders for cross-functional decision-making and issue resolution\nCollaborate and communicate cross-functionally to measure and achieve program goals\nLead the generation of program assumptions for annual resource allocation and budgeting across research and development functions\nEffectively manage meetings, inclusive of stakeholder management and preparation, communication, and management of action items, decisions and follow-through.\nCommunicate complex topics to stakeholders through effective storytelling and content creation\nDevelop integrated program planning timelines and reporting. Define critical path activities, interdependencies, and anticipate bottlenecks.\nProactively manage project risks, through identification, assessment, mitigation and escalation of gaps, challenges, and potential roadblocks\nIdentify, communicate, and manage resource constraints, synergies, and redundancies.\nEstablish team operating norms and identify opportunities to improve team performance\nWork with Portfolio and Program leadership team to build, manage, coach and retain PM staff.\nKnowledge and Skills:\nComprehensive knowledge of project and portfolio management principles, best practices, tools, technology and methods\nLeadership experience managing cross-functional teams\nExcellent written and oral communication skills, including well-developed presentation skills\nComprehensive pharmaceutical drug discovery and development knowledge across multiple disciplines\nExceptional organizational skills and an ability to manage multiple priorities\nStrong collaboration skills to effectively interact with internal or external stakeholders at all levels of the organization\nAbility to work in a fast-paced and collaborative environment and manage multiple concurrent projects with a high degree of independence \nExperience in carrying out Risk Analysis, Decision Analysis and Contingency Planning\nA desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society\nAbility to embody the Vertex Core Values of Uncompromising Commitment to Patients, Fearless Pursuit of Excellence, Innovation is Our Lifeblood, and “We” Wins\nEducation and Experience: \nTypically requires an advanced degree in Life Sciences or a relevant field, (PhD degree preferred or strong demonstration of equivalent combination of relevant educational and professional training)\nTypically requires 8 years of experience, or the equivalent combination of education and experience\nExperience with drug development on cross-functional teams and/or in more than one function\nAt Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.\nPay Range:\n$162,200 - $243,200Disclosure Statement:\nThe range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.\nAt Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.\nFlex Designation:\nHybrid-Eligible Or On-Site EligibleFlex Eligibility Status:\nIn this Hybrid-Eligible role, you can choose to be designated as: \n1. Hybrid: work remotely up to two days per week; or select\n2. On-Site: work five days per week on-site with ad hoc flexibility.\nNote: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.\n#LI-Hybrid\nCompany Information\nVertex is a global biotechnology company that invests in scientific innovation.\nVertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.\nAny applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ","description_format":"text","description_chars":6461,"description_truncated":false,"requirements":{"experience_years_min":8,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":["Continuous learning","Equity"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Prescription Drugs","Cell & Gene Therapy","Rare Disease Therapeutics"],"lifecycle":[{"event":"open","at":"2026-11-05T21:14:50Z"}],"visa":[{"country":"US","licensed_sponsor":true,"adverts_offering_sponsorship_24m":0,"sanctioned_now":false,"evidence":"H-1B filings in 12 months: 174 · green card filings: 21","filings_12m":174,"filings_prev_12m":187,"green_card_filings_12m":21,"median_offered_wage_usd":131423,"route":null,"cap_exempt":false,"checked_at":"2026-11-09T07:32:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":63,"band":"ok","label":"Likely open","p_open":1,"p_active":0.632,"p_room":1,"age_days":4,"expected_fill_days":38,"reasons":["conf:5","stale_co","velocity","win:early","comp:brand"],"computed_at":"2026-11-10T06:52:35Z"},"pay":{"stated_usd_annual":243200,"is_top_pay":true},"html_url":"https://alion.io/job/vertex-pharmaceuticals-portfolio-program-management-associate-director","json_url":"https://alion.io/job/vertex-pharmaceuticals-portfolio-program-management-associate-director.json","meta":{"generated_at":"2026-11-10T09:02:47Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":21057,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-11T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.1,"usd":0.01,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":5871},"rest":"https://alion.io/mcp/rest/get_company?id=5871"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fvertex-pharmaceuticals-portfolio-program-management-associate-director"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":2,"usd":0.2},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fvertex-pharmaceuticals-portfolio-program-management-associate-director"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.1,"usd":0.01},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fvertex-pharmaceuticals-portfolio-program-management-associate-director"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/vertex-pharmaceuticals-portfolio-program-management-associate-director\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fvertex-pharmaceuticals-portfolio-program-management-associate-director"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3836641}},{"tool":"search_jobs","arguments":{"company":"vrtx.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3836641},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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