{"id":2860669,"url":"https://alion.io/job/vivodyne-senior-scientist","title":"Senior Scientist","company":{"id":687550,"name":"Vivodyne","domain":"vivodyne.com","url":"https://alion.io/company/vivodyne","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":{"grade":"B","score":75,"open_postings":3,"ghost_share":0,"stale_share":1,"repost_share":0,"time_to_fill_p50_days":null,"computed_at":"2026-10-22T06:10:10Z"}},"role":"Science & Research","role_family":"Science & Research","seniority":"senior","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["San Francisco, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":120000,"max":160000,"currency":"USD","period":"year","gross":null,"usd_annual":160000},"salary_estimate":null,"experience_years_min":2,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Cell Culture","optional":false},{"name":"Confocal Microscopy","optional":true},{"name":"Flow Cytometry","optional":true},{"name":"Multimodal AI","optional":true},{"name":"Next-Generation Sequencing","optional":true}],"status":"live","first_seen_at":"2026-10-19T13:48:08Z","employer_posted_date":"2026-10-19","last_verified_at":"2026-10-22T09:23:37Z","board_verified":true,"closed_at":null,"days_open":2,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":2},"description":"Vivodyne creates human data before clinical trials.\nWe accelerate the successful discovery, design, and development of human therapeutics by testing on large, lab-grown human organ tissues at massive scale, driving technological advancement at the convergence of novel biology, robotics, and AI. We identify and validate new therapeutic targets and de-risk new therapeutic assets by producing clinically translatable multi-omic data from our proprietary, physiologically-realistic human organ tissues at unprecedented scale, speed, and quality. This enables us to produce more human data than all clinical trials in the U.S. combined. We’re financially backed by some of the most selective and successful venture funds, and we have already partnered with a majority of the top 10 multinational pharmaceutical companies to discover and develop better, safer drugs and dramatically reduce the burden of animal testing.\nwww.vivodyne.com\nRole\nThis is a full-time, onsite role in San Francisco.\nYou will lead the development, optimization, and scaling of advanced human tissue models to be deployed within Vivodyne’s automated experimentation platform for therapeutic discovery. \nAs a Senior Scientist on the Bioengineering team, you will own a scientific program centered around a specific tissue system or disease model, driving projects from early biological hypothesis generation through mature, scalable workflows. You will work cross-functionally with bioengineers, computational biologists, AI scientists, roboticists, hardware engineers, and translational researchers to develop next-generation human tissue platforms that enable deeper understanding of human biology and drug response.\nThis role requires exceptional experimental rigor, deep technical expertise in complex cell culture systems, strong scientific reasoning, and the ability to make sound, data-driven decisions in ambiguous and fast-moving environments. We are looking for a scientist who combines deep biological intuition with disciplined execution and who consistently designs experiments that produce clear, actionable conclusions.\nResponsibilities\nTissue Model Development with Experimental Excellence\nLead development and optimization of complex in vitro human tissue models using primary human cells and advanced 3D culture systems - deep experience in intestine, lung or immuno-biology is a bonus.\nDesign, execute, and interpret rigorous experiments with clear success criteria and proper controls to improve tissue phenotype, stability, scalability, reproducibility, and biological relevance.\nDrive mechanistic understanding of tissue behavior through multimodal characterization approaches.\nTroubleshoot difficult experimental problems systematically using first-principles reasoning and quantitative analysis.\nPlatform Scaling & Automation\nPartner closely with robotics and hardware teams to adapt tissue workflows for automated operation and large-scale experimentation.\nSupport transfer of tissue models from exploratory R&D into reliable production-grade workflows.\nIdentify sources of experimental variability and implement strategies to improve robustness and reproducibility.\nContribute to the development of scalable assay and tissue characterization pipelines.\nRequirements and Expectations\nRequired Qualifications\nPhD in bioengineering, cell biology, molecular biology, physiology, developmental biology, genetics, or a related field. A focus on gut, lung or immuno-biology a large plus.\n2-4 years of industry experience following PhD and/or postdoctoral training in biotechnology, therapeutics, tissue engineering, or related fields.\nDemonstrated record of scientific achievement through high-impact publications, patents, awards, or other evidence of advancing the state of the art in your field. \nDeep expertise in mammalian cell culture, including primary human cells and complex 3D tissue models.\nExpertise with modern biomolecular and cellular characterization techniques including:\nconfocal imaging,\nflow cytometry,\ntranscriptomic workflows,\nproteomic assays,\nnext-generation sequencing workflows,\nand interpretation of resulting datasets.\nProven ability to independently drive complex technical programs in fast-paced R&D environments.\nPreferred Qualifications\nPreference given to candidates with direct experience in building complex human models of gut and lung biology or in immunology / complex models of cancer biology. \nExperience developing organoid, organ-on-chip, or microphysiological systems.\nExperience scaling biological workflows into automated or high-throughput systems.\nExperience working with multimodal datasets integrating imaging, transcriptomics, proteomics, and functional readouts.\nVivodyne, Inc. is an equal opportunity employer. Vivodyne complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.\nCompensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.\nPay Range\n$120,000—$160,000 USD","description_format":"text","description_chars":5150,"description_truncated":false,"requirements":{"experience_years_min":2,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Drug Discovery","Drug Discovery AI"],"lifecycle":[{"event":"open","at":"2026-10-19T16:09:02Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 1","filings_12m":1,"filings_prev_12m":0,"green_card_filings_12m":0,"median_offered_wage_usd":252500,"route":null,"cap_exempt":false,"checked_at":"2026-10-15T11:24:14+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)"],"filings_for_role_12m":0}],"liveness":{"score":86,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.86,"p_room":1,"age_days":2,"expected_fill_days":36,"reasons":["conf:0","win:early"],"computed_at":"2026-10-22T06:10:10Z"},"pay":{"stated_usd_annual":160000,"is_top_pay":true},"html_url":"https://alion.io/job/vivodyne-senior-scientist","json_url":"https://alion.io/job/vivodyne-senior-scientist.json","meta":{"generated_at":"2026-10-22T11:39:54Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":9709,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-23T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":687550},"rest":"https://alion.io/mcp/rest/get_company?id=687550"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fvivodyne-senior-scientist"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fvivodyne-senior-scientist"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fvivodyne-senior-scientist"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/vivodyne-senior-scientist\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fvivodyne-senior-scientist"}]}