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EARLY ONSET FAMILIAL We have developed this special section of the Alzforum website to provide a resource for all who share an intense interest in familial early-onset AD (eFAD).
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α-synuclein A53T "M83" Mouse (Tg)
IMSR_JAX:004479 Overview M83 mice were generated by inserting a transgene containing the human A53T α-synuclein, driven by the mouse prion protein promoter ( Giasson et al., 2002 ). These mice are generally viable and fertile, and overall normal in size (
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