Aneesh Sathe

Single-cell omics methods provide sparse, noisy measurements of high-dimensional cell states, whose underlying distributions remain poorly understood, raising an urgent need for exploratory analysis and visualization methods. However, current methods are

The Birth of Thickets described the thicket as an emergent niche you cannot found; this is the practice of traversing one. Tuan gives Space and Place, Debord the dérive, Feyerabend permission, Manaugh the move: using an idea through its ventilation shafts

Over the past year, the Contraptions club has been reading through history-from Giordano Bruno and Montaigne to Spinoza, Adam Smith, and Hume. We are now using using Venkatesh Rao's Divergence Machine framework as a lens to make sense of the modern world.

This is the third and final part of the Thicket Series: Part 1: Logic of the Thicket and the Unsearchable Web Part 2: The Architecture of Resistance The history of the working subject might be best understood not as a ledger of wages or a sequence of indu

The seventeenth-century Hague, the mid-twentieth-century Levant, and the digital terraforming of 2025 have a shared preoccupation with the "Average." Whether it is the theologian's way or predictive stats, control begins by smoothing out the landscape. Th