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News
Kallyope rebrands as TriGemX Bio, narrows focus to migraine from gut-brain axis and obesity work
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TriGemX Bio Announces $94M Financing and Initiation of Phase 3 Trials for Elismetrep, A Potential First-in-Class Treatment for Migraine
New Investors TCGX and Viking Global Investors Join World-Class Syndicate Initial Elismetrep Phase 3 Results Anticipated in Mid-2027 Company Relaunching with Key Leadership Appointments and Company Name Change TriGemX Bio (formerly known as Kallyope), a b
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TriGemX Bio Announces $94M Financing and Initiation of Phase 3 Trials for Elismetrep, A Potential First-in-Class Treatment for Migraine
NEW YORK, October 01, 2026--TriGemX Bio (formerly known as Kallyope), a biotechnology company focused on developing a first-in-class medicine for the treatment of migraine, today announced the closing of a $94 million financing co-led by The Column Group,
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Kallyope Presents New Data on Novel TRPM8 Channel Blocker Elismetrep for the Acute Treatment for Migraine at the American Headache Society 68th Annual Scientific Meeting
Results contribute to growing body of evidence in support of elismetrep, a TRPM8 migraine-associated channel blocker (MACB), to help address the debilitating impact of migraine Novel liquid-filled softgel capsule (LSGC) formulation results in earlier and
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Kallyope's Phase 2b Study of Elismetrep, A Novel Approach for Treating Migraine, Presented at the American Academy of Neurology Annual Meeting
Data validate the efficacy, safety, and tolerability of elismetrep, an investigational first-in-class TRPM8 migraine-associated channel blocker(MACB), as a novel approach for treating migraine Potential for a new mechanism to help address the debilitating
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Kallyope's Phase 2b Study of Elismetrep, A Novel Approach for Treating Migraine, Presented at the American Academy of Neurology Annual Meeting
NEW YORK, April 22, 2026--Kallyope is a late-stage biotechnology company focused on developing innovative migraine and metabolic disease therapies for health challenges faced by hundreds of millions of people globally. Today, the Company presented results
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Kallyope to Present Phase 2b Study Results for Elismetrep for the Acute Treatment of Migraine at the 2026 American Academy of Neurology Annual Meeting
Clinically meaningful data establishes proof of concept for elismetrep as a promising therapeutic candidate for migraine and its progression into registrational studies anticipated to initiate mid-2026 Data validate novel TRPM8 migraine-associated channel
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People

Nancy Thornberry
Executive Officer, Director

Kenneth Clark
Executive Officer

William Rieflin
Director

Terry McGuire
Director

Tom Maniatis
Director

Joshua Wolfe
Director

Tim Kutzkey
Director
Names and roles come from public filings, company registers and the company's own site. Is this you? Correct or remove · How we handle this data
Offices
Where the company hires and what each office is for
Cities
1
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Countries
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New York
United States
HQ
Contact Us
50-200 est. staff
Kallyope Inc. | New York, NY 10016
Financials
Total raised
$28.1M
Latest round
Venture - Series Unknown
Funding rounds
1
Funding rounds
| Round | Announced | Amount | |
|---|---|---|---|
| Venture - Series Unknown | 2015 | $28.1M | Details |
