Manifold Bio
Drug Discovery
6open roles
$182kmedian advertised pay
3backers · FPV Ventures, Horizons Ventures
10+team · employees, estimated range
Overview
Manifold Bio has built the first high-throughput in vivo (HTV) discovery engine—combining massively multiplexed in vivo screening and AI-powered design to create targeted biologics.
How Manifold Bio hires
Truth index
B 75/100
Ghost roles
0%
Stale roles
100%
Reposted roles
0%
Manifold Bio scores B on the Alion truth index (A is best, E worst), measured over 5 open roles re-checked against its own hiring board: 0% look like ghost listings, 100% have gone stale and 0% are the same role posted again. It measures how much of what this employer publishes turns into a real, finite search - not the employer as a workplace. How the index is computed
Funding and backers
Team
11-50
employees, estimated range
Hiring now
8
+2 posted in 30 days
Backers
3
FPV Ventures, Horizons Ventures
Momentum
20/100
hiring for its size, a new city
Last sign of life
1 mo ago
a posting or a news item
The story so fareach stage dated by its source: the company's releases, the press, registers, filings
Jan 2019
Website went live first capture in the Wayback Machine
Tractionpublic signals, read monthly
Web presence
top 2%
of 133.2M domains by links, Common Crawl
Backed byfrom the funds' portfolios and accelerator catalogs
FPV Ventures 
Horizons Ventures 
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Jobs
$60k – $70k per year · In office · Contractor · Boston
Benchling
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$118k – $138k per year · Equity · In office · PhD · Boston
Antibody Engineering
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$118k – $138k per year · Equity · In office · 4+ years exp · PhD · Boston
Python
AI Agents
Machine Learning
DevOps
GCP
AWS
Unix
Life Sciences
Next-Generation Sequencing
Antibody Engineering
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$195k – $239k per year · Equity · In office · 10+ years exp · PhD · Boston
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$165k – $275k per year · Equity · In office · 2+ years exp · Bachelor's Degree · Boston · San Francisco
AI Agents
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$140k – $225k per year · Equity · In office · 2+ years exp · Bachelor's Degree · Boston · San Francisco
Python
Scikit-learn
JAX
Pandas
NumPy
PyTorch
Machine Learning
DevOps
GCP
Git
AWS
Docker
Kubernetes
Analytics
ETL/ELT
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Salary insights
Compensation ranges based on this company's open jobs
Median
$182k
Typical range
$70k – $350k
Open positions
8
6
Jobs
Junior
33.3%
Middle
16.7%
Senior
33.3%
Staff
16.7%
| Level | Jobs | Median | Typical range |
|---|---|---|---|
| Junior | 2 | $250k | $225k – $275k |
| Middle | 1 | $138k | $138k |
| Senior | 2 | $237k | $123k – $350k |
| Staff | 1 | $239k | $239k |
Highest paying role
Sr. Director / VP, Business Development
$350k
Normalized to USD per year
All salaries at Manifold Bio
By role, level and city, against the market · 8 jobs with pay
Growth
Hiring Momentum
37/100
Slowing
Open positions
8
0 opened / 0 closed in 30 days
Median time-to-fill
92 days
faster than 12% of the market
ATS activity
Every ~5 hours
Today
Hiring Dynamics
0%
Hiring Focus
The percentage next to each role is its share of the company's job openings over the last 90 days; the arrow shows the shift versus the previous period.
Administrative
33% ▼
Sales
33% ▲
Biotech
33% ▲
Activity Timeline
Added LIMS to stack
Oct 2026
Added GraphPad Prism to stack
Oct 2026
Added Confocal Microscopy to stack
Oct 2026
Added Benchling to stack
Oct 2026
Added Next-Generation Sequencing to stack
Oct 2026
Added Antibody Engineering to stack
Oct 2026
New location: San Francisco
Oct 2026
Tech stack
Technologies named in job postings at Manifold Bio over the last 12 months, by layer, with the share of postings for each.
Technologies in use
21
Postings analysed
6
Stack modernity
73/100
Languages
Python
Frameworks & libraries
JAX
NumPy
Pandas
PyTorch
Cloud & platforms
AWS
GCP
Unix
Kubernetes
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Full Manifold Bio tech stack
21 technologies · by team · pay by technology · changes · similar stacks
Connections
List
Graph
Found in company registers, site code, DNS and hiring. Each connection shows how sure we are and the evidence, with its source and date.
Shared investors
Click a company to open it. Dashed lines are likely connections. The second step of the network is part of the Pro plan.
Owner
Same company
Same group
Likely
News
From NYSE: Anthropic called out Manifold Bio as a key feedback provider when they announced Claude for life sciences recently. CEO Gleb Kuznetsov explains, and updates us on the brain shuttle program
He describes why manifold is focused on in vivo work, even to the extent that it is trying to develop a
Read more
Report
Manifold Bio Demonstrates Million-Scale Experimental Validation of AI-Driven Protein Binder Design with NVIDIA
BOSTON, March 16, 2026--Manifold Bio, a platform therapeutics company pioneering direct-to-vivo drug discovery, today announced a joint study with NVIDIA to validate Proteina-Complexa, NVIDIA
Read more
Report
Manifold Bio And Roche Form Strategic Collaboration To Develop Next-Generation Brain Shuttles For Neurological Diseases
Manifold Bio, a platform therapeutics company pioneering AI-guided drug discovery using direct-to-vivo measurement, announced a major research collaboration and license agreement with Roche to develop multiple next-generation blood-brain barrier (BBB) shu
Read more
Report
Molecular 'barcodes' could break thru in vivo bottleneck
Manifold Bio's molecular machinery could let a hundred molecules be tested simultaneously in a single living system, potentially upending the whole process.
Read more
Report
Offices
Where the company hires and what each office is for
Cities
2
Hiring now
2
Countries
1
Busiest office
Boston
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Headquarters
Builds here
Office with open vacancies
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Boston
United States
HQ
Boston Office
8 open roles 3 posted in 90 days 25% engineering 10-50 est. staff $195k Avg Salary
hires for AI/ML, Product, Administrative
San Francisco
United States
Engineering / R&D
San Francisco Office
2 open roles 50% engineering 1-10 est. staff $250k Avg Salary
hires for AI/ML, Product