Resolian

Resolian developed a hybrid immunocapture nano-LC-MS/MS assay to quantify STAT6, a translational biomarker for RNA-degrading therapeutics, across human tissue types. bioanalysis BackgroundSTAT6 is a transcription factor activated downstream of IL-4/IL-13

Resolian developed and validated a simple, high-throughput HPLC-MS/MS method for simultaneous quantitation of acalabrutinib and its active metabolite ACP-5862 in human plasma, achieving an LLOQ of 1.00 ng/mL with a 20-minute extraction and no carryover. b

Resolian developed the first hybrid LC-MS/MS method to achieve 50 pg/mL sensitivity for a duplex siRNA and its N-1 metabolite in human plasma, setting a new benchmark for regulated siRNA bioanalysis. bioanalysis Authors: Andy (Hongfang) Xue, Danyang Wang,

Resolian's Andy Xue on what makes ADC bioanalysis uniquely demanding, and how the team builds scalable, drug-tolerant methods across ADCs, PDCs, and AOCs. bioanalysis CASE STUDY Expert Voice: Andy XueStrategies for ADC Bioanalysis: Building for Complexity

Resolian's Ashley Phillips on why LC-MS outperforms immunoassays for protein biomarkers, from isoform differentiation to drug-tolerant assay design. bioanalysis CASE STUDY Expert Voice: Ashley PhillipsLC-MS for Protein Biomarkers: Precision Where Immunoas

Resolian developed an extraction-free, direct-to-qPCR workflow that accurately quantifies therapeutic oligonucleotides across plasma and multiple tissue types using a single calibration curve, reducing hands-on time and cost without compromising performan

Resolian developed and validated an MSD-based bridging ECLIA method for analysing anti-drug antibodies against a GalNAc-conjugated siRNA therapeutic, evaluating both MSD and Gyrolab platforms for different GalNAc-conjugated siRNA therapeutics and providin

Choosing a bioanalytical partner for biopharma startups? Follow these 5 proven criteria to protect your timeline, data quality, and regulatory readiness. BLOG If you're a lean biopharma team heading toward IND or your first clinical trial, choosing the ri

See how Resolian pairs light microscopy and SEM to reveal structure from macro view to nanoscale, and what this means for your next investigation. ANALYTICAL SCIENCES Author: Jack Aston BackgroundThis showcase study examines a fragment of peacock butterfl

Running a global program? Here's how to choose a bioanalytical CRO for global drug development, from lab footprint to phase-to-phase handoffs. BLOG Running a drug development program across more than one country multiplies almost every risk you already ha