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Overview
Science and philosophy. Click to read Technotheoria, by Sebastian Jensen, a Substack publication with thousands of subscribers.
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I am looking for work
BackgroundAfter graduating from college, I started helping people write research papers, whether it was doing the data analysis, writing the drafts, or communicating with peer reviewers. I did this for three years, from 2023-2025. I stopped doing this aft
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What hair loss treatments work?
The first line treatments of hair loss are minoxidil, finasteride, and dutasteride.The problem is that all of these medications kind of suck. A decent amount of people either can't tolerate them or don't want to take them due to concerns about side effect
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Semax: underrated
Semax has been grouped into the category of experimental, foreign peptides that nobody really trusts or understands. Which is sad, because Semax's evidence as a neuroprotective agent, even in humans, is well documented. Nobody bothered to read the studies
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Nootropics: a fraught, but promising science
The skeptics lost. Effective nootropics exist, particualrly in the form of stimulants and catecholaminergics. Drugs that help maintain cognitive function past reproductive years almost certainly exist, but I don't know of one that has been proven to be hi
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Alternatives to human growth hormone
TL;DR:"It just works": tesamorelinEfficacy, at a cost: MK-677Efficacy, but of uncertain safety: CJC with DACSafe, possibly effective: ipamorelin, CJC with no DACBesides directly supplementing with growth hormone, drugs can also target ghrelin or GHRHR rec
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How much protein is optimal for bodybuilding?
There isn't a settled answer to this question, but my intuition is that its lower than commonly believed. The convention is for protein doses to be weight normalised, which is fine as a heuristic, I suppose. It falls apart when it comes to individuals. A
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Creatine: possible nootropic
Mechanistically, the story seems pretty clear. Cerebral creatine deficiency is a documented cause of intellectual disability. Supplementing creatine increases the concentration of creatine in the brain (#1, #2). Some people, even without a monogenic disor
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Bromantane: overhyped
The hype around this drug is massive. A stimulant with anti-anxiety, anti-fatigue, and nootropic effects at the same time. It has no substantial crash, tolerance, or dependence. It's well-tolerated and has few side effects1. Most anti-anxiety drugs either
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Caffeine: works in some people
There's a separate debate about caffeine beyond its main effec - whether taking caffeine is still worth it when you factor in the dependence caffeine produces as a drug. That question doesn't interest me, but I'll explain the logic. When we run studies on
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Modafinil: the clean stimulant
It lasts longer than nicotine, builds less tolerance than caffeine, changes mood less than amphetamines, and is less dangerous than cocaine. It's extremely effective at what it does, which is keeping people awake. So much that it's possible to pull an all
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