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Salary
$180k – $243k per year
Location
Hybrid (Pleasanton, United States)
Seniority
Architect · 10+ years exp
Visa
H-1B filings in 12 months: 30 · for this role: 12 · green card filings: 12
Employment
Full-Time

Confirmed on the employer's own hiring board on Nov 1, 2026. First seen by Alion on Oct 19, 2026.

Overview
Company
Impact
Profile match
10x Genomics builds instruments, consumables and software for single cell and spatial biology research. Its Chromium and Visium platforms let scientists profile gene expression at the resolution of individual cells and tissue coordinates. The company is widely used across academic labs and pharmaceutical discovery programmes.

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It’s a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

Our software enables our scientists to better understand human health, such as pinpointing the differences between a cancer and normal cell and the genomic sequences the body makes in response to infection. We’ve built an ecosystem of powerful software, hardware, microfluidics, and chemistry to create products that are used by researchers around the world, including 96 of the top 100 global research institutions.

Our teams are encouraged to follow their passions and pursue new ideas in an inclusive and dynamic environment. The discoveries we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.

About The Role

We are looking for an outstanding Staff Systems Architect who will serve as a critical technical leader within our CRM Systems Team. In this role, you will be responsible for modernizing our CRM and commercial data infrastructure, which is foundational to streamlining quoting workflows, automating manual processes, and enabling self-service tooling. You will play a vital role in sustaining current business operations while driving the execution of major upcoming commercial initiatives and supporting our evolving business models.

You will foster a deep partnership and highly productive relationship between PE (Productivity Engineering) and commercial business teams, working on a portfolio of PE projects and services with a focus on 10x’s global Sales, Customer Support, and E-Commerce business processes. By translating complex business needs into scalable technical solutions, you will ensure frictionless workflows for our stakeholders and guarantee the stability and scalability of our existing Salesforce environment.

What you will be doing

  • Modernize CRM Architecture: Provide technical oversight to modernize our CRM and commercial data infrastructure, delivering the complex backend architecture required to support new commercial programs, evolving business models, and future tiered service offerings.

  • Accelerate Revenue Velocity: Streamline Account, Opportunity, and Quote workflows while rationalizing pricebook management to reduce quoting friction for Sales and enable scalable pricing practices.

  • Drive Process Automation: Establish Salesforce as the single definitive source of truth by automating manual processes across the sales and customer success lifecycle, eliminating bottlenecks between Sales and Customer Success.

  • Leverage AI Technologies: Explore and integrate AI and Large Language Model (LLM) solutions within our CRM ecosystem to enhance sales productivity, streamline customer support workflows, and unlock advanced data insights.

  • Empower Stakeholders via Self-Service: Build and deliver robust self-service tooling that allows Support and Platform PM teams to handle routine tasks independently, returning engineering bandwidth to strategic initiatives.

  • Strategic Partnership: Collaborate closely with Marketing, Sales, Customer Service, and PE leadership to align IT solutions with major strategic goals, including business scaling and customer onboarding.

  • System Administration & Support: Ensure that production support for the CRM track meets SLA expectations, responding to issues and incidents while providing day-to-day administration and support of key systems like Salesforce, Marketo, etc.

  • Project Leadership: Lead projects from inception through delivery, functioning as a business partner to model, design, and build solutions that improve 10x’s CRM processes.

Minimum Qualifications

  • Bachelor’s degree in the field of computer science or information systems.

  • 10 years of experience in system architecture, analysis, design, and development of complex CRM solutions.

  • 7 years of technical experience and project management in a fast-growing, technology organization, with deep exposure to cloud-based (SaaS) business models.

  • Hands-on experience and architectural knowledge of Salesforce Sales and Service Cloud, CPQ, and Marketo.

  • Familiarity with modern AI capabilities and Large Language Models (LLMs), including practical experience or strong conceptual understanding of how to apply them to CRM platforms (e.g., Salesforce Einstein, generative AI for support).

  • Deep understanding of key sales and support business processes (Lead-to-Order, Quote-to-Contract, Campaign-to-cash, CPQ, etc.).

  • Proven track record in process automation, self-service tooling creation, and rationalizing complex quoting/pricebook workflows.

Preferred Skills & Experience

  • Strong problem-solving and analytical/critical thinking skills needed, as well as exceptional interpersonal skills.

  • An excellent communicator with exceptional active listening skills, with the ability to convey complex ideas in a clear, concise fashion to technical and non-technical audiences.

  • An obsession over performance, user experience, efficiency, and infrastructure scalability.

  • RPA deployment experience.

  • Salesforce Certifications (e.g., Application Architect, System Architect, AI Associate).

Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, and experience. At 10x, base pay is also just one component of the Company’s total compensation package. This role is also eligible for 10x’s equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company’s total compensation package.

USD 179,900-243,300 / year

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.

10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

Please be aware of recruitment scams impersonating 10x Genomics. All recruiting communication will come from email addresses @10xgenomics.com. We also want to encourage you to apply to 10x Genomics positions directly on our careers site, https://careers.kula.ai/10xgenomics?pid=171812447059&domain=10xgenomics.com or from reputable third party sites, such as LinkedIn or Indeed. We will never request payment or sensitive personal information during the recruiting process.

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