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Salary
$94k – $117k per year
Location
Hybrid (Seattle, United States)
Seniority
Middle
Visa
Filed H-1B visas in the last two years

Confirmed on the employer's own hiring board on Oct 13, 2026. First seen by Alion on Sep 10, 2026.

Overview
Company
Impact
Profile match
MEASURING, PREDICTING, ANDENGINEERING PROTEIN INTERACTIONS at Scale. A-Alpha Bio harnesses synthetic biology and machine learning to precisely engineer high-impact medicines.
Backed by Madrona, Xontogeny

A-Alpha Bio is an early-stage, rapidly growing biotechnology platform company headquartered in Seattle, WA. We are focused on building the foundational data layer for AI-driven protein engineering. We provide biopharma companies and model builders with access to ground truth experimental datasets, including affinity and structure, for training, benchmarking and validating AI protein models. In parallel, we apply our data and models directly with select partners to engineer next-generation dual-specific and molecular glue therapeutics, and to discover and optimize differentiated biologics.

This role is not open to remote applicants and would require relocation to Seattle, WA.

Starting Salary Range: $94,000 - $117,000 annually

Exemption Status:  Exempt

Location Expectations: Hybrid (1-3 onsite days per week)

Reporting To: Senior Alliance Manager

Role Description

A-Alpha Bio is seeking an Alliance Manager II to support the execution and success of external scientific and strategic partnerships. This is a heavily cross-functional role with a significant external-facing component. Successful candidates will have exceptional communication and organizational skills, comfort navigating scientific and operational complexity, and the ability to foster productive working relationships. 

Key Responsibilities

  • Serve as day-to-day liaison between the company and assigned external partners, providing clear, consistent communication and alignment on goals, timelines, and deliverables, both internally and externally.
  • Coordinate closely with internal scientific leads and functional teams to support execution of partnership workplans.
  • Prepare and circulate meeting agendas, materials, and meeting minutes for joint governance meetings, technical updates, and ad hoc partner discussions.
  • Track partnership obligations, milestones, and decision points; flag risks, misalignments, or emerging issues to senior commercial leadership.
  • Support interpretation and execution of collaboration agreements, including scope changes, data-sharing provisions, and reporting requirements, in coordination with other commercial team members.
  • Contribute to the preparation of SOWs, partner reports, updates, and presentations that clearly communicate progress, challenges, and next steps.
  • Communicate status, changes, and forecasts to the Leadership Team.
  • Foster positive, professional relationships with partner teams, promoting trust, transparency, and productive collaboration.
  • Contribute to continuous improvement of alliance management processes, templates, and best practices.  

Qualifications & Experience

Required

  • Bachelor’s degree in a related scientific or business field with 5+ years of experience supporting external partnerships in the life sciences; PhD in a related scientific or business field; or an equivalent combination of education or experience.
  • Demonstrated ability to manage multiple stakeholders and workstreams simultaneously.
  • Strong written and verbal communication skills, with the ability to convey complex scientific or operational information clearly.
  • High level of organization, attention to detail, and follow-through.
  • Comfort operating in a fast-paced, ambiguous environment.
  • Ability to collaborate effectively with cross-functional scientific and business teams. 

Preferred

  • Advanced degree (Master’s and/or PhD) in a scientific discipline.
  • MBA degree.
  • Specific experience in alliance management, project management, or scientific program management.
  • Experience in drug discovery, protein science, genomics, machine learning, biologics, large datasets, and/or computational biology.  

In 2018, A-Alpha Bio spun out of the University of Washington’s Institute for Protein Design and Center for Synthetic Biology - both communities filled with brilliant and highly entrepreneurial scientists. Since the company’s inception, we have built and scaled AlphaSeq, our high-throughput platform for quantitatively measuring protein-protein interactions at unprecedented scale. What began as a technology for generating large, standardized affinity datasets has grown into a broader data engine for AI-driven protein engineering. New members of the team should expect a fast-paced, highly dynamic, and interdisciplinary work environment. We are building a diverse, meritocratic, and supportive team that shares our values of speaking the truth, shooting for the moon, taking the reins, playing for the team, and improving the world.

A-Alpha Bio is headquartered in a custom designed lab and office space in downtown Seattle’s Belltown neighborhood. We are fortunate to be situated in a region that is renowned for its premier outdoor activities, including hiking, biking, climbing, skiing, kayaking, sailing, and more. At A-Alpha, you’ll find many who love the outdoors, but also gamers, amateur chefs, explorers, sports fans, bakers, crafters, photographers, brewers, jetsetters, animal lovers, and artists. Whatever your passions, you belong at A-Alpha Bio! 

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